The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Leucine-rich Repeat Variant
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 79: transportin-3 isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
12 Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI)
(2 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
12 Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI) Q9Y5L0 (/IPI)
(2 more)
Nuclear import signal receptor activity GO:0061608
Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.
12 Q9Y5L0 (/TAS) Q9Y5L0 (/TAS) Q9Y5L0 (/TAS) Q9Y5L0 (/TAS) Q9Y5L0 (/TAS) Q9Y5L0 (/TAS) Q9Y5L0 (/TAS) Q9Y5L0 (/TAS) Q9Y5L0 (/TAS) Q9Y5L0 (/TAS)
(2 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q6P2B1 (/ISO)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
13 Q9VQG0 (/IDA) Q9Y5L0 (/IDA) Q9Y5L0 (/IDA) Q9Y5L0 (/IDA) Q9Y5L0 (/IDA) Q9Y5L0 (/IDA) Q9Y5L0 (/IDA) Q9Y5L0 (/IDA) Q9Y5L0 (/IDA) Q9Y5L0 (/IDA)
(3 more)
MRNA processing GO:0006397
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
3 A0A2R8QLV3 (/IMP) Q5RHV1 (/IMP) Q7ZW13 (/IMP)
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
3 A0A2R8QLV3 (/IMP) Q5RHV1 (/IMP) Q7ZW13 (/IMP)
T cell differentiation GO:0030217
The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
3 A0A2R8QLV3 (/IGI) Q5RHV1 (/IGI) Q7ZW13 (/IGI)
T cell differentiation GO:0030217
The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
3 A0A2R8QLV3 (/IMP) Q5RHV1 (/IMP) Q7ZW13 (/IMP)
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
1 Q6P2B1 (/ISO)
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
1 Q6P2B1 (/ISS)
Regulation of mRNA splicing, via spliceosome GO:0048024
Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.
1 Q9VQG0 (/IDA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
36 A0A024R794 (/IDA) A0A024R794 (/IDA) A0A024R794 (/IDA) A0A024R794 (/IDA) A0A024R794 (/IDA) A0A024R794 (/IDA) A0A024R794 (/IDA) A0A024R794 (/IDA) A0A024R794 (/IDA) A0A024R794 (/IDA)
(26 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9VQG0 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9VQG0 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 Q6P2B1 (/ISO)
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