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CATH Superfamily 1.25.10.10

Leucine-rich Repeat Variant

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Leucine-rich Repeat Variant
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 455: Karyopherin beta

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
 14 Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA)
(4 more)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
 14 Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS)
(4 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NLS-bearing protein import into nucleus GO:0006607
The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear envelope.
 14 Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA) Q8I3M5 (/IDA)
(4 more)
Nucleocytoplasmic transport GO:0006913
The directed movement of molecules between the nucleus and the cytoplasm.
 14 Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS)
(4 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nuclear pore GO:0005643
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
 14 Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS)
(4 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 14 Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS) Q8I3M5 (/TAS)
(4 more)
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