The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Leucine-rich Repeat Variant
".
FunFam 1432: Cell death abnormality protein 12
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q8STE5 (/IPI) |
|
Phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547
Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
|
1 | Q8STE5 (/IDA) |
|
Rho GTPase binding GO:0017048
Interacting selectively and non-covalently with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton.
|
1 | Q8STE5 (/IPI) |
|
SH3 domain binding GO:0017124
Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
|
1 | Q8STE5 (/TAS) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q8STE5 (/IPI) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | A8XEZ1 (/ISS) |
|
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
|
1 | Q8STE5 (/IPI) |
|
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
|
1 | A8XEZ1 (/ISS) |
|
Proline-rich region binding GO:0070064
Interacting selectively and non-covalently with a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein.
|
1 | Q8STE5 (/IPI) |
|
Proline-rich region binding GO:0070064
Interacting selectively and non-covalently with a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein.
|
1 | A8XEZ1 (/ISS) |
Showing 1 to 10 of 12 entries
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Establishment of mitotic spindle orientation GO:0000132
A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.
|
1 | Q8STE5 (/IGI) |
|
Phagocytosis, engulfment GO:0006911
The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.
|
1 | Q8STE5 (/IMP) |
|
Phagocytosis, engulfment GO:0006911
The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.
|
1 | A8XEZ1 (/ISS) |
|
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
|
1 | Q8STE5 (/IDA) |
|
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
1 | Q8STE5 (/IMP) |
|
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
1 | A8XEZ1 (/ISS) |
|
Regulation of cell migration GO:0030334
Any process that modulates the frequency, rate or extent of cell migration.
|
1 | Q8STE5 (/IMP) |
|
Actin cytoskeleton reorganization GO:0031532
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.
|
1 | Q8STE5 (/IMP) |
|
Actin cytoskeleton reorganization GO:0031532
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.
|
1 | A8XEZ1 (/ISS) |
|
Gonad morphogenesis GO:0035262
The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.
|
1 | Q8STE5 (/IMP) |
Showing 1 to 10 of 20 entries
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8STE5 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | A8XEZ1 (/ISS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q8STE5 (/IDA) |
|
Guanyl-nucleotide exchange factor complex GO:0032045
A protein complex that stimulates the exchange of guanyl nucleotides associated with a GTPase.
|
1 | Q8STE5 (/IDA) |
Showing 1 to 4 of 4 entries
