The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Functional domain of the splicing factor Prp18
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Pre-mRNA-splicing factor 18

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Generation of catalytic spliceosome for second transesterification step GO:0000350
Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing.
8 P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA)
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
8 P33411 (/IMP) P33411 (/IMP) P33411 (/IMP) P33411 (/IMP) P33411 (/IMP) P33411 (/IMP) P33411 (/IMP) P33411 (/IMP)
Nuclear retention of unspliced pre-mRNA at the site of transcription GO:0071048
The process involved in retention of incorrectly or incompletely spliced pre-mRNA within the nucleus at the site of transcription.
8 P33411 (/IGI) P33411 (/IGI) P33411 (/IGI) P33411 (/IGI) P33411 (/IGI) P33411 (/IGI) P33411 (/IGI) P33411 (/IGI)
Nuclear retention of unspliced pre-mRNA at the site of transcription GO:0071048
The process involved in retention of incorrectly or incompletely spliced pre-mRNA within the nucleus at the site of transcription.
8 P33411 (/IMP) P33411 (/IMP) P33411 (/IMP) P33411 (/IMP) P33411 (/IMP) P33411 (/IMP) P33411 (/IMP) P33411 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
U5 snRNP GO:0005682
A ribonucleoprotein complex that contains small nuclear RNA U5.
8 P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA)
U4/U6 x U5 tri-snRNP complex GO:0046540
A ribonucleoprotein complex formed by the association of the U4/U6 and U5 small nuclear ribonucleoproteins.
8 P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA)
U2-type post-spliceosomal complex GO:0071021
A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6.
8 P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA) P33411 (/IDA)
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