The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Phospholipase A2 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 4: Group XIIA secretory phospholipase A2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium-dependent phospholipase A2 activity GO:0047498
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+.
5 Q9BZM1 (/NAS) Q9BZM1 (/NAS) Q9BZM1 (/NAS) Q9BZM1 (/NAS) Q9BZM1 (/NAS)
Phospholipase A2 activity GO:0004623
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate.
1 Q9EPR2 (/IDA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphatidic acid biosynthetic process GO:0006654
The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
5 Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS)
Phosphatidylglycerol acyl-chain remodeling GO:0036148
Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains.
5 Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS)
Phosphatidylinositol acyl-chain remodeling GO:0036149
Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains.
5 Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS)
Phosphatidylserine acyl-chain remodeling GO:0036150
Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains.
5 Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS)
Phosphatidylcholine acyl-chain remodeling GO:0036151
Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains.
5 Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS)
Phosphatidylethanolamine acyl-chain remodeling GO:0036152
Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains.
5 Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS)
Lipid catabolic process GO:0016042
The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
1 Q9EPR2 (/IC)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
5 Q9BZM1 (/NAS) Q9BZM1 (/NAS) Q9BZM1 (/NAS) Q9BZM1 (/NAS) Q9BZM1 (/NAS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
5 Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS) Q9BZM1 (/TAS)
CATH-Gene3D is a Global Biodata Core Resource Learn more...