The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Phospholipase A2 domain
".
FunFam 1: Basic phospholipase A2 homolog
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 17 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phospholipase A2 activity GO:0004623
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate.
|
13 |
A8E2V8 (/IDA)
P00625 (/IDA)
P14555 (/IDA)
P14555 (/IDA)
P86169 (/IDA)
P86803 (/IDA)
P86804 (/IDA)
P86805 (/IDA)
P86806 (/IDA)
P86907 (/IDA)
(3 more) |
|
Phospholipase A2 activity GO:0004623
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate.
|
4 | O15496 (/TAS) P14423 (/TAS) Q9NZK7 (/TAS) Q9UNK4 (/TAS) |
|
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
|
3 | P51433 (/IDA) Q9WVF6 (/IDA) Q9WVF6 (/IDA) |
|
Calcium-dependent phospholipase A2 activity GO:0047498
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+.
|
3 | P14555 (/TAS) P14555 (/TAS) P39877 (/TAS) |
|
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
2 | P14555 (/IDA) P14555 (/IDA) |
|
Heparan sulfate proteoglycan binding GO:0043395
Interacting selectively and non-covalently with a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.
|
2 | Q9WVF6 (/IDA) Q9WVF6 (/IDA) |
|
Calcium-dependent phospholipase A2 activity GO:0047498
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+.
|
2 | P14423 (/IDA) P51433 (/IDA) |
|
Phospholipase activity GO:0004620
Catalysis of the hydrolysis of a glycerophospholipid.
|
1 | Q9QXX3 (/IMP) |
|
Phospholipase activity GO:0004620
Catalysis of the hydrolysis of a glycerophospholipid.
|
1 | O15496 (/ISS) |
|
Phospholipase A2 activity GO:0004623
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate.
|
1 | Q9QXX3 (/ISO) |
Showing 1 to 10 of 17 entries
There are 70 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phospholipid metabolic process GO:0006644
The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.
|
8 | A8E2V8 (/IDA) P00625 (/IDA) P14423 (/IDA) P14555 (/IDA) P14555 (/IDA) P86907 (/IDA) P97391 (/IDA) Q9QZT4 (/IDA) |
|
Phosphatidic acid biosynthetic process GO:0006654
The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
|
7 | O15496 (/TAS) P14555 (/TAS) P14555 (/TAS) P39877 (/TAS) Q9BZM2 (/TAS) Q9NZK7 (/TAS) Q9UNK4 (/TAS) |
|
Phosphatidylglycerol acyl-chain remodeling GO:0036148
Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains.
|
7 | O15496 (/TAS) P14555 (/TAS) P14555 (/TAS) P39877 (/TAS) Q9BZM2 (/TAS) Q9NZK7 (/TAS) Q9UNK4 (/TAS) |
|
Phosphatidylinositol acyl-chain remodeling GO:0036149
Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains.
|
7 | O15496 (/TAS) P14555 (/TAS) P14555 (/TAS) P39877 (/TAS) Q9BZM2 (/TAS) Q9NZK7 (/TAS) Q9UNK4 (/TAS) |
|
Phosphatidylserine acyl-chain remodeling GO:0036150
Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains.
|
7 | O15496 (/TAS) P14555 (/TAS) P14555 (/TAS) P39877 (/TAS) Q9BZM2 (/TAS) Q9NZK7 (/TAS) Q9UNK4 (/TAS) |
|
Phosphatidylcholine acyl-chain remodeling GO:0036151
Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains.
|
7 | O15496 (/TAS) P14555 (/TAS) P14555 (/TAS) P39877 (/TAS) Q9BZM2 (/TAS) Q9NZK7 (/TAS) Q9UNK4 (/TAS) |
|
Phosphatidylethanolamine acyl-chain remodeling GO:0036152
Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains.
|
7 | O15496 (/TAS) P14555 (/TAS) P14555 (/TAS) P39877 (/TAS) Q9BZM2 (/TAS) Q9NZK7 (/TAS) Q9UNK4 (/TAS) |
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
|
6 | P86169 (/IDA) P86453 (/IDA) P86803 (/IDA) P86804 (/IDA) P86805 (/IDA) P86806 (/IDA) |
|
Envenomation resulting in induction of edema in other organism GO:0044398
A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the swelling of soft tissues of the bitten organism as a result of excess water accumulation.
|
5 | P62022 (/IDA) P62022 (/IDA) P62022 (/IDA) P62022 (/IDA) P62022 (/IDA) |
|
Envenomation resulting in positive regulation of platelet aggregation in other organism GO:0044478
A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of platelet aggregation in the bitten organism.
|
5 | P62022 (/IDA) P62022 (/IDA) P62022 (/IDA) P62022 (/IDA) P62022 (/IDA) |
Showing 1 to 10 of 70 entries
There are 19 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
11 |
P62022 (/IDA)
P62022 (/IDA)
P62022 (/IDA)
P62022 (/IDA)
P62022 (/IDA)
P86169 (/IDA)
P86453 (/IDA)
P86803 (/IDA)
P86804 (/IDA)
P86805 (/IDA)
(1 more) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
10 | A8E2V8 (/TAS) O15496 (/TAS) P00625 (/TAS) P14555 (/TAS) P14555 (/TAS) P39877 (/TAS) Q9BZM2 (/TAS) Q9NZK7 (/TAS) Q9QZT3 (/TAS) Q9UNK4 (/TAS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
3 | O15496 (/IDA) P14555 (/IDA) P14555 (/IDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P14555 (/HDA) P14555 (/HDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
2 | P14555 (/IDA) P14555 (/IDA) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
2 | P14555 (/TAS) P14555 (/TAS) |
|
Extracellular space of host GO:0043655
The space within a host but external to the plasma membrane of host cells, e.g. within host bloodstream.
|
2 | A8E2V8 (/TAS) P00625 (/TAS) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
2 | P14423 (/IDA) P51433 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
2 | P14555 (/HDA) P14555 (/HDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | Q9BZM2 (/NAS) |
Showing 1 to 10 of 19 entries
