The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Erythrocyte membrane protein 1, PfEMP1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
37 C6KTF7 (/TAS) C6KTF7 (/TAS) Q8I1V6 (/TAS) Q8I1V6 (/TAS) Q8I1V7 (/TAS) Q8I220 (/TAS) Q8I220 (/TAS) Q8I2C4 (/TAS) Q8I2C4 (/TAS) Q8I2E3 (/TAS)
(27 more)
Host cell surface receptor binding GO:0046789
Interacting selectively and non-covalently with a receptor on the host cell surface.
5 Q8I519 (/TAS) Q8IIZ5 (/TAS) Q8IIZ5 (/TAS) Q8IK37 (/TAS) Q8IK37 (/TAS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Modulation by symbiont of host erythrocyte aggregation GO:0020013
Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes.
37 C6KTF7 (/TAS) C6KTF7 (/TAS) Q8I1V6 (/TAS) Q8I1V6 (/TAS) Q8I1V7 (/TAS) Q8I220 (/TAS) Q8I220 (/TAS) Q8I2C4 (/TAS) Q8I2C4 (/TAS) Q8I2E3 (/TAS)
(27 more)
Antigenic variation GO:0020033
Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system.
37 C6KTF7 (/TAS) C6KTF7 (/TAS) Q8I1V6 (/TAS) Q8I1V6 (/TAS) Q8I1V7 (/TAS) Q8I220 (/TAS) Q8I220 (/TAS) Q8I2C4 (/TAS) Q8I2C4 (/TAS) Q8I2E3 (/TAS)
(27 more)
Cytoadherence to microvasculature, mediated by symbiont protein GO:0020035
The adherence of symbiont-infected erythrocytes to microvascular endothelium via symbiont proteins embedded in the membrane of the erythrocyte.
37 C6KTF7 (/TAS) C6KTF7 (/TAS) Q8I1V6 (/TAS) Q8I1V6 (/TAS) Q8I1V7 (/TAS) Q8I220 (/TAS) Q8I220 (/TAS) Q8I2C4 (/TAS) Q8I2C4 (/TAS) Q8I2E3 (/TAS)
(27 more)
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
37 C6KTF7 (/TAS) C6KTF7 (/TAS) Q8I1V6 (/TAS) Q8I1V6 (/TAS) Q8I1V7 (/TAS) Q8I220 (/TAS) Q8I220 (/TAS) Q8I2C4 (/TAS) Q8I2C4 (/TAS) Q8I2E3 (/TAS)
(27 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Host cell plasma membrane GO:0020002
The plasma membrane surrounding a host cell.
37 C6KTF7 (/TAS) C6KTF7 (/TAS) Q8I1V6 (/TAS) Q8I1V6 (/TAS) Q8I1V7 (/TAS) Q8I220 (/TAS) Q8I220 (/TAS) Q8I2C4 (/TAS) Q8I2C4 (/TAS) Q8I2E3 (/TAS)
(27 more)
Infected host cell surface knob GO:0020030
Protrusion that develops in the plasma membrane of a parasitized erythrocyte. An example of this component is found in Plasmodium species.
37 C6KTF7 (/TAS) C6KTF7 (/TAS) Q8I1V6 (/TAS) Q8I1V6 (/TAS) Q8I1V7 (/TAS) Q8I220 (/TAS) Q8I220 (/TAS) Q8I2C4 (/TAS) Q8I2C4 (/TAS) Q8I2E3 (/TAS)
(27 more)
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