The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: Syntaxin family protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
SNAP receptor activity GO:0005484
Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.
12 P32867 (/IPI) P32867 (/IPI) P32867 (/IPI) P39926 (/IPI) P39926 (/IPI) P39926 (/IPI) P39926 (/IPI) P39926 (/IPI) P39926 (/IPI) P39926 (/IPI)
(2 more)
Phosphatidic acid binding GO:0070300
Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
12 P32867 (/IDA) P32867 (/IDA) P32867 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA)
(2 more)
SNARE binding GO:0000149
Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
3 P32867 (/IPI) P32867 (/IPI) P32867 (/IPI)
SNAP receptor activity GO:0005484
Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.
3 P32867 (/IDA) P32867 (/IDA) P32867 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P32867 (/IPI) P32867 (/IPI) P32867 (/IPI)
Phosphatidylinositol-4,5-bisphosphate binding GO:0005546
Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
3 P32867 (/IDA) P32867 (/IDA) P32867 (/IDA)
Phosphatidylinositol-3,4-bisphosphate binding GO:0043325
Interacting selectively and non-covalently with phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions.
3 P32867 (/IDA) P32867 (/IDA) P32867 (/IDA)
Phosphatidylinositol-3,5-bisphosphate binding GO:0080025
Interacting selectively and non-covalently with phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions.
3 P32867 (/IDA) P32867 (/IDA) P32867 (/IDA)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ascospore-type prospore assembly GO:0031321
During ascospore formation, the process in which each haploid nucleus becomes encapsulated by a double membrane.
12 P32867 (/IGI) P32867 (/IGI) P32867 (/IGI) P39926 (/IGI) P39926 (/IGI) P39926 (/IGI) P39926 (/IGI) P39926 (/IGI) P39926 (/IGI) P39926 (/IGI)
(2 more)
Golgi to plasma membrane transport GO:0006893
The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.
9 P39926 (/TAS) P39926 (/TAS) P39926 (/TAS) P39926 (/TAS) P39926 (/TAS) P39926 (/TAS) P39926 (/TAS) P39926 (/TAS) P39926 (/TAS)
Vesicle fusion GO:0006906
Fusion of the membrane of a transport vesicle with its target membrane.
9 P39926 (/TAS) P39926 (/TAS) P39926 (/TAS) P39926 (/TAS) P39926 (/TAS) P39926 (/TAS) P39926 (/TAS) P39926 (/TAS) P39926 (/TAS)
Vesicle fusion GO:0006906
Fusion of the membrane of a transport vesicle with its target membrane.
3 P32867 (/IDA) P32867 (/IDA) P32867 (/IDA)
Ascospore formation GO:0030437
The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota).
3 P32867 (/IMP) P32867 (/IMP) P32867 (/IMP)
Ascospore-type prospore assembly GO:0031321
During ascospore formation, the process in which each haploid nucleus becomes encapsulated by a double membrane.
3 P32867 (/IMP) P32867 (/IMP) P32867 (/IMP)
SNARE complex assembly GO:0035493
The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
3 P32867 (/IMP) P32867 (/IMP) P32867 (/IMP)
Protein secretion GO:0009306
The controlled release of proteins from a cell.
2 Q59YF0 (/IMP) Q59YF0 (/IMP)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
2 Q59YF0 (/IMP) Q59YF0 (/IMP)
Golgi to plasma membrane transport GO:0006893
The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.
1 Q9USH7 (/ISO)
Ascospore formation GO:0030437
The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota).
1 Q9USH7 (/IGI)
Ascospore-type prospore membrane assembly GO:0032120
The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed.
1 Q9USH7 (/IGI)
Ascospore-type prospore membrane assembly GO:0032120
The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed.
1 Q9USH7 (/IMP)
Prospore membrane biogenesis GO:0099097
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a prospore membrane.
1 Q9USH7 (/IMP)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Prospore membrane GO:0005628
The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe.
13 P32867 (/IDA) P32867 (/IDA) P32867 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA)
(3 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
13 P32867 (/IDA) P32867 (/IDA) P32867 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA) P39926 (/IDA)
(3 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
12 P32867 (/HDA) P32867 (/HDA) P32867 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA)
(2 more)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
12 P32867 (/HDA) P32867 (/HDA) P32867 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA)
(2 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
9 P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA) P39926 (/HDA)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
3 P32867 (/IDA) P32867 (/IDA) P32867 (/IDA)
SNARE complex GO:0031201
A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25.
3 P32867 (/IDA) P32867 (/IDA) P32867 (/IDA)
SNARE complex GO:0031201
A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25.
3 P32867 (/IMP) P32867 (/IMP) P32867 (/IMP)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9USH7 (/IDA)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
1 Q9USH7 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 Q9USH7 (/HDA)
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
1 Q9USH7 (/IDA)
Plasma membrane raft GO:0044853
A membrane raft that is part of the plasma membrane.
1 Q9USH7 (/IDA)
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
1 Q9USH7 (/IDA)
Prospore membrane leading edge GO:0070056
The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization.
1 Q9USH7 (/IDA)
Prospore membrane spindle pole body attachment site GO:0070057
The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus.
1 Q9USH7 (/IDA)
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