The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 41: Pep12p

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
SNAP receptor activity GO:0005484
Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.
8 P32854 (/IDA) P32854 (/IDA) P32854 (/IDA) P32854 (/IDA) P32854 (/IDA) P32854 (/IDA) P32854 (/IDA) P32854 (/IDA)
SNAP receptor activity GO:0005484
Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.
8 P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P32854 (/IPI) P32854 (/IPI) P32854 (/IPI) P32854 (/IPI) P32854 (/IPI) P32854 (/IPI) P32854 (/IPI) P32854 (/IPI)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Vacuole inheritance GO:0000011
The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.
8 P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP)
Golgi to vacuole transport GO:0006896
The directed movement of substances from the Golgi to the vacuole.
8 P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP)
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
8 P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP)
Protein localization by the Cvt pathway GO:0032258
A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast.
8 P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
8 P32854 (/HDA) P32854 (/HDA) P32854 (/HDA) P32854 (/HDA) P32854 (/HDA) P32854 (/HDA) P32854 (/HDA) P32854 (/HDA)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
8 P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
8 P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP) P32854 (/IMP)
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