The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 44: Short stop, isoform K

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
23 A0A0B4K718 (/ISS) A0A0B4K788 (/ISS) A0A0B4K7P8 (/ISS) A0A0B4K7Y9 (/ISS) A0A0B4K867 (/ISS) A0A0B4K869 (/ISS) A1Z9I8 (/ISS) A1Z9I9 (/ISS) A1Z9J0 (/ISS) A1Z9J1 (/ISS)
(13 more)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
23 A0A0B4K718 (/TAS) A0A0B4K788 (/TAS) A0A0B4K7P8 (/TAS) A0A0B4K7Y9 (/TAS) A0A0B4K867 (/TAS) A0A0B4K869 (/TAS) A1Z9I8 (/TAS) A1Z9I9 (/TAS) A1Z9J0 (/TAS) A1Z9J1 (/TAS)
(13 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
23 A0A0B4K718 (/IPI) A0A0B4K788 (/IPI) A0A0B4K7P8 (/IPI) A0A0B4K7Y9 (/IPI) A0A0B4K867 (/IPI) A0A0B4K869 (/IPI) A1Z9I8 (/IPI) A1Z9I9 (/IPI) A1Z9J0 (/IPI) A1Z9J1 (/IPI)
(13 more)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
23 A0A0B4K718 (/TAS) A0A0B4K788 (/TAS) A0A0B4K7P8 (/TAS) A0A0B4K7Y9 (/TAS) A0A0B4K867 (/TAS) A0A0B4K869 (/TAS) A1Z9I8 (/TAS) A1Z9I9 (/TAS) A1Z9J0 (/TAS) A1Z9J1 (/TAS)
(13 more)
Showing 1 to 4 of 4 entries

There are 28 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Microtubule cytoskeleton organization GO:0000226
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
23 A0A0B4K718 (/IMP) A0A0B4K788 (/IMP) A0A0B4K7P8 (/IMP) A0A0B4K7Y9 (/IMP) A0A0B4K867 (/IMP) A0A0B4K869 (/IMP) A1Z9I8 (/IMP) A1Z9I9 (/IMP) A1Z9J0 (/IMP) A1Z9J1 (/IMP)
(13 more)
Microtubule cytoskeleton organization GO:0000226
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
23 A0A0B4K718 (/TAS) A0A0B4K788 (/TAS) A0A0B4K7P8 (/TAS) A0A0B4K7Y9 (/TAS) A0A0B4K867 (/TAS) A0A0B4K869 (/TAS) A1Z9I8 (/TAS) A1Z9I9 (/TAS) A1Z9J0 (/TAS) A1Z9J1 (/TAS)
(13 more)
Microtubule bundle formation GO:0001578
A process that results in a parallel arrangement of microtubules.
23 A0A0B4K718 (/IMP) A0A0B4K788 (/IMP) A0A0B4K7P8 (/IMP) A0A0B4K7Y9 (/IMP) A0A0B4K867 (/IMP) A0A0B4K869 (/IMP) A1Z9I8 (/IMP) A1Z9I9 (/IMP) A1Z9J0 (/IMP) A1Z9J1 (/IMP)
(13 more)
Microtubule-based process GO:0007017
Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
23 A0A0B4K718 (/NAS) A0A0B4K788 (/NAS) A0A0B4K7P8 (/NAS) A0A0B4K7Y9 (/NAS) A0A0B4K867 (/NAS) A0A0B4K869 (/NAS) A1Z9I8 (/NAS) A1Z9I9 (/NAS) A1Z9J0 (/NAS) A1Z9J1 (/NAS)
(13 more)
Negative regulation of microtubule depolymerization GO:0007026
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
23 A0A0B4K718 (/IMP) A0A0B4K788 (/IMP) A0A0B4K7P8 (/IMP) A0A0B4K7Y9 (/IMP) A0A0B4K867 (/IMP) A0A0B4K869 (/IMP) A1Z9I8 (/IMP) A1Z9I9 (/IMP) A1Z9J0 (/IMP) A1Z9J1 (/IMP)
(13 more)
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
23 A0A0B4K718 (/IMP) A0A0B4K788 (/IMP) A0A0B4K7P8 (/IMP) A0A0B4K7Y9 (/IMP) A0A0B4K867 (/IMP) A0A0B4K869 (/IMP) A1Z9I8 (/IMP) A1Z9I9 (/IMP) A1Z9J0 (/IMP) A1Z9J1 (/IMP)
(13 more)
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
23 A0A0B4K718 (/TAS) A0A0B4K788 (/TAS) A0A0B4K7P8 (/TAS) A0A0B4K7Y9 (/TAS) A0A0B4K867 (/TAS) A0A0B4K869 (/TAS) A1Z9I8 (/TAS) A1Z9I9 (/TAS) A1Z9J0 (/TAS) A1Z9J1 (/TAS)
(13 more)
Sensory organ development GO:0007423
The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure.
23 A0A0B4K718 (/TAS) A0A0B4K788 (/TAS) A0A0B4K7P8 (/TAS) A0A0B4K7Y9 (/TAS) A0A0B4K867 (/TAS) A0A0B4K869 (/TAS) A1Z9I8 (/TAS) A1Z9I9 (/TAS) A1Z9J0 (/TAS) A1Z9J1 (/TAS)
(13 more)
Open tracheal system development GO:0007424
The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.
23 A0A0B4K718 (/IMP) A0A0B4K788 (/IMP) A0A0B4K7P8 (/IMP) A0A0B4K7Y9 (/IMP) A0A0B4K867 (/IMP) A0A0B4K869 (/IMP) A1Z9I8 (/IMP) A1Z9I9 (/IMP) A1Z9J0 (/IMP) A1Z9J1 (/IMP)
(13 more)
Open tracheal system development GO:0007424
The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.
23 A0A0B4K718 (/TAS) A0A0B4K788 (/TAS) A0A0B4K7P8 (/TAS) A0A0B4K7Y9 (/TAS) A0A0B4K867 (/TAS) A0A0B4K869 (/TAS) A1Z9I8 (/TAS) A1Z9I9 (/TAS) A1Z9J0 (/TAS) A1Z9J1 (/TAS)
(13 more)
Showing 1 to 10 of 28 entries

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Astral microtubule GO:0000235
Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.
23 A0A0B4K718 (/IDA) A0A0B4K788 (/IDA) A0A0B4K7P8 (/IDA) A0A0B4K7Y9 (/IDA) A0A0B4K867 (/IDA) A0A0B4K869 (/IDA) A1Z9I8 (/IDA) A1Z9I9 (/IDA) A1Z9J0 (/IDA) A1Z9J1 (/IDA)
(13 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
23 A0A0B4K718 (/HDA) A0A0B4K788 (/HDA) A0A0B4K7P8 (/HDA) A0A0B4K7Y9 (/HDA) A0A0B4K867 (/HDA) A0A0B4K869 (/HDA) A1Z9I8 (/HDA) A1Z9I9 (/HDA) A1Z9J0 (/HDA) A1Z9J1 (/HDA)
(13 more)
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
23 A0A0B4K718 (/NAS) A0A0B4K788 (/NAS) A0A0B4K7P8 (/NAS) A0A0B4K7Y9 (/NAS) A0A0B4K867 (/NAS) A0A0B4K869 (/NAS) A1Z9I8 (/NAS) A1Z9I9 (/NAS) A1Z9J0 (/NAS) A1Z9J1 (/NAS)
(13 more)
Microtubule GO:0005874
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
23 A0A0B4K718 (/IDA) A0A0B4K788 (/IDA) A0A0B4K7P8 (/IDA) A0A0B4K7Y9 (/IDA) A0A0B4K867 (/IDA) A0A0B4K869 (/IDA) A1Z9I8 (/IDA) A1Z9I9 (/IDA) A1Z9J0 (/IDA) A1Z9J1 (/IDA)
(13 more)
Microtubule GO:0005874
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
23 A0A0B4K718 (/TAS) A0A0B4K788 (/TAS) A0A0B4K7P8 (/TAS) A0A0B4K7Y9 (/TAS) A0A0B4K867 (/TAS) A0A0B4K869 (/TAS) A1Z9I8 (/TAS) A1Z9I9 (/TAS) A1Z9J0 (/TAS) A1Z9J1 (/TAS)
(13 more)
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
23 A0A0B4K718 (/IDA) A0A0B4K788 (/IDA) A0A0B4K7P8 (/IDA) A0A0B4K7Y9 (/IDA) A0A0B4K867 (/IDA) A0A0B4K869 (/IDA) A1Z9I8 (/IDA) A1Z9I9 (/IDA) A1Z9J0 (/IDA) A1Z9J1 (/IDA)
(13 more)
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
23 A0A0B4K718 (/TAS) A0A0B4K788 (/TAS) A0A0B4K7P8 (/TAS) A0A0B4K7Y9 (/TAS) A0A0B4K867 (/TAS) A0A0B4K869 (/TAS) A1Z9I8 (/TAS) A1Z9I9 (/TAS) A1Z9J0 (/TAS) A1Z9J1 (/TAS)
(13 more)
Muscle tendon junction GO:0005927
A cell-substrate junction found at the terminal anchorage site of skeletal muscle cells to tendons.
23 A0A0B4K718 (/IDA) A0A0B4K788 (/IDA) A0A0B4K7P8 (/IDA) A0A0B4K7Y9 (/IDA) A0A0B4K867 (/IDA) A0A0B4K869 (/IDA) A1Z9I8 (/IDA) A1Z9I9 (/IDA) A1Z9J0 (/IDA) A1Z9J1 (/IDA)
(13 more)
Filopodium GO:0030175
Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
23 A0A0B4K718 (/IDA) A0A0B4K788 (/IDA) A0A0B4K7P8 (/IDA) A0A0B4K7Y9 (/IDA) A0A0B4K867 (/IDA) A0A0B4K869 (/IDA) A1Z9I8 (/IDA) A1Z9I9 (/IDA) A1Z9J0 (/IDA) A1Z9J1 (/IDA)
(13 more)
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
23 A0A0B4K718 (/IDA) A0A0B4K788 (/IDA) A0A0B4K7P8 (/IDA) A0A0B4K7Y9 (/IDA) A0A0B4K867 (/IDA) A0A0B4K869 (/IDA) A1Z9I8 (/IDA) A1Z9I9 (/IDA) A1Z9J0 (/IDA) A1Z9J1 (/IDA)
(13 more)
Showing 1 to 10 of 13 entries
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