CATH Superfamily 1.20.58.1770
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 4: Rab interacting lysosomal protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q5ND29 (/IPI) Q5ND29 (/IPI) Q96NA2 (/IPI) |
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
|
2 | Q5ND29 (/ISO) Q5ND29 (/ISO) |
Small GTPase binding GO:0031267
Interacting selectively and non-covalently with a small monomeric GTPase.
|
2 | Q5ND29 (/ISO) Q5ND29 (/ISO) |
Dynein light intermediate chain binding GO:0051959
Interacting selectively and non-covalently with a light intermediate chain of the dynein complex.
|
2 | Q5ND29 (/ISO) Q5ND29 (/ISO) |
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
|
1 | Q96NA2 (/IPI) |
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
|
1 | Q96NA2 (/TAS) |
Small GTPase binding GO:0031267
Interacting selectively and non-covalently with a small monomeric GTPase.
|
1 | Q96NA2 (/IPI) |
Dynein light intermediate chain binding GO:0051959
Interacting selectively and non-covalently with a light intermediate chain of the dynein complex.
|
1 | Q96NA2 (/IPI) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Endosome to lysosome transport GO:0008333
The directed movement of substances from endosomes to lysosomes.
|
2 | Q5ND29 (/ISO) Q5ND29 (/ISO) |
Regulation of multivesicular body size GO:0010796
Any process that modulates the volume of a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles.
|
2 | Q5ND29 (/ISO) Q5ND29 (/ISO) |
Endosome transport via multivesicular body sorting pathway GO:0032509
The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment.
|
2 | Q5ND29 (/ISO) Q5ND29 (/ISO) |
Negative regulation of protein catabolic process GO:0042177
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
2 | Q5ND29 (/ISO) Q5ND29 (/ISO) |
Early endosome to late endosome transport GO:0045022
The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
|
2 | Q5ND29 (/ISO) Q5ND29 (/ISO) |
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
2 | Q5ND29 (/ISO) Q5ND29 (/ISO) |
Intralumenal vesicle formation GO:0070676
The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.
|
2 | Q5ND29 (/ISO) Q5ND29 (/ISO) |
Endosome to lysosome transport GO:0008333
The directed movement of substances from endosomes to lysosomes.
|
1 | Q96NA2 (/IMP) |
Regulation of multivesicular body size GO:0010796
Any process that modulates the volume of a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles.
|
1 | Q96NA2 (/IDA) |
Protein transport GO:0015031
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q96NA2 (/NAS) |
Antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
|
1 | Q96NA2 (/TAS) |
Endosome transport via multivesicular body sorting pathway GO:0032509
The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment.
|
1 | Q96NA2 (/IDA) |
Negative regulation of protein catabolic process GO:0042177
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
1 | Q96NA2 (/IDA) |
Early endosome to late endosome transport GO:0045022
The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
|
1 | Q96NA2 (/IMP) |
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
1 | Q96NA2 (/IMP) |
Intralumenal vesicle formation GO:0070676
The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.
|
1 | Q96NA2 (/IMP) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q5ND29 (/HDA) Q5ND29 (/HDA) |
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
2 | Q5ND29 (/ISO) Q5ND29 (/ISO) |
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
|
2 | Q5ND29 (/ISO) Q5ND29 (/ISO) |
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
2 | Q5ND29 (/IDA) Q5ND29 (/IDA) |
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
1 | Q96NA2 (/IDA) |
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
1 | Q96NA2 (/NAS) |
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
1 | Q96NA2 (/TAS) |
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
|
1 | Q96NA2 (/IDA) |
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
|
1 | Q96NA2 (/NAS) |