The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Actin interacting protein 3, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Bud site selection protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
3 P41697 (/IDA) P41697 (/IDA) P41697 (/IDA)
Cytoskeletal regulatory protein binding GO:0005519
Interacting selectively and non-covalently with any protein involved in modulating the reorganization of the cytoskeleton.
3 P41697 (/IDA) P41697 (/IDA) P41697 (/IDA)
Cytoskeletal regulatory protein binding GO:0005519
Interacting selectively and non-covalently with any protein involved in modulating the reorganization of the cytoskeleton.
3 P41697 (/IPI) P41697 (/IPI) P41697 (/IPI)
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
3 P41697 (/IMP) P41697 (/IMP) P41697 (/IMP)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
1 O13735 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 O13735 (/IPI)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Establishment of cell polarity GO:0030010
The specification and formation of anisotropic intracellular organization or cell growth patterns.
4 A0A1D8PE85 (/IMP) P41697 (/IMP) P41697 (/IMP) P41697 (/IMP)
Budding cell apical bud growth GO:0007118
Growth at the tip of a bud, in a cell that reproduces by budding.
3 P41697 (/IGI) P41697 (/IGI) P41697 (/IGI)
Budding cell apical bud growth GO:0007118
Growth at the tip of a bud, in a cell that reproduces by budding.
3 P41697 (/IMP) P41697 (/IMP) P41697 (/IMP)
Bipolar cellular bud site selection GO:0007121
The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell.
3 P41697 (/IMP) P41697 (/IMP) P41697 (/IMP)
Pseudohyphal growth GO:0007124
A pattern of cell growth that occurs in conditions of nitrogen limitation and abundant fermentable carbon source. Cells become elongated, switch to a unipolar budding pattern, remain physically attached to each other, and invade the growth substrate.
3 P41697 (/IMP) P41697 (/IMP) P41697 (/IMP)
Astral microtubule organization GO:0030953
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles.
3 P41697 (/IMP) P41697 (/IMP) P41697 (/IMP)
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
3 P41697 (/IMP) P41697 (/IMP) P41697 (/IMP)
Extrachromosomal circular DNA localization involved in cell aging GO:0034652
A process in which extrachromosomal circular DNA molecules are transported to, or maintained in, a specific location in cells contributing to their aging.
3 P41697 (/IMP) P41697 (/IMP) P41697 (/IMP)
Actin filament bundle assembly GO:0051017
The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
3 P41697 (/IGI) P41697 (/IGI) P41697 (/IGI)
Actin filament bundle assembly GO:0051017
The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
3 P41697 (/IMP) P41697 (/IMP) P41697 (/IMP)
Positive regulation of formin-nucleated actin cable assembly GO:0090338
Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
3 P41697 (/IDA) P41697 (/IDA) P41697 (/IDA)
Positive regulation of formin-nucleated actin cable assembly GO:0090338
Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
3 P41697 (/IGI) P41697 (/IGI) P41697 (/IGI)
Positive regulation of actin cytoskeleton reorganization GO:2000251
Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization.
3 P41697 (/IGI) P41697 (/IGI) P41697 (/IGI)
Positive regulation of actin cytoskeleton reorganization GO:2000251
Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization.
3 P41697 (/IMP) P41697 (/IMP) P41697 (/IMP)
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
1 A0A1D8PE85 (/IMP)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
1 A0A1D8PE85 (/IMP)
Positive regulation of actin nucleation GO:0051127
Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
1 O13735 (/ISO)

There are 15 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Incipient cellular bud site GO:0000131
The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence.
3 P41697 (/IDA) P41697 (/IDA) P41697 (/IDA)
Polarisome GO:0000133
Protein complex that plays a role in determining cell polarity by directing the localized assembly of actin filaments at polarization sites; in Saccharomyces the polarisome includes Bni1p, Spa2p, Pea2p, and Bud6p.
3 P41697 (/IDA) P41697 (/IDA) P41697 (/IDA)
Prospore membrane GO:0005628
The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe.
3 P41697 (/HDA) P41697 (/HDA) P41697 (/HDA)
Spindle pole body GO:0005816
The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
3 P41697 (/IDA) P41697 (/IDA) P41697 (/IDA)
Cellular bud tip GO:0005934
The end of a cellular bud distal to the site of attachment to the mother cell.
3 P41697 (/IDA) P41697 (/IDA) P41697 (/IDA)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
3 P41697 (/IDA) P41697 (/IDA) P41697 (/IDA)
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
3 P41697 (/HDA) P41697 (/HDA) P41697 (/HDA)
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
3 P41697 (/IDA) P41697 (/IDA) P41697 (/IDA)
Hyphal tip GO:0001411
The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation.
1 A0A1D8PE85 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O13735 (/HDA)
Actin cap GO:0030478
Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell. An example of this is the actin cap found in Saccharomyces cerevisiae.
1 O13735 (/ISO)
Hyphal tip polarisome GO:0031562
Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha.
1 A0A1D8PE85 (/IDA)
Growing cell tip GO:0035838
The region at either end of the longest axis of a cylindrical or elongated cell, where polarized growth occurs.
1 O13735 (/IDA)
Non-growing cell tip GO:0035839
A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures.
1 O13735 (/IDA)
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
1 O13735 (/IDA)
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