The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Single helix bin
".
FunFam 6: cGMP-dependent protein kinase 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 15 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
CGMP-dependent protein kinase activity GO:0004692
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cGMP.
|
12 |
P0C605 (/IDA)
P0C605 (/IDA)
Q03043 (/IDA)
Q13976 (/IDA)
Q13976 (/IDA)
Q13976 (/IDA)
Q13976 (/IDA)
Q13976 (/IDA)
Q13976 (/IDA)
Q13976 (/IDA)
(2 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
11 |
P0C605 (/IPI)
P0C605 (/IPI)
Q13976 (/IPI)
Q13976 (/IPI)
Q13976 (/IPI)
Q13976 (/IPI)
Q13976 (/IPI)
Q13976 (/IPI)
Q13976 (/IPI)
Q13976 (/IPI)
(1 more) |
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
9 | Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) |
Calcium channel regulator activity GO:0005246
Modulates the activity of a calcium channel.
|
9 | Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) |
Calcium channel regulator activity GO:0005246
Modulates the activity of a calcium channel.
|
4 | O77676 (/ISS) P00516 (/ISS) P0C605 (/ISS) P0C605 (/ISS) |
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
2 | P0C605 (/IDA) P0C605 (/IDA) |
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
2 | P0C605 (/ISO) P0C605 (/ISO) |
CGMP-dependent protein kinase activity GO:0004692
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cGMP.
|
2 | P0C605 (/ISO) P0C605 (/ISO) |
CGMP-dependent protein kinase activity GO:0004692
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cGMP.
|
2 | O77676 (/ISS) P00516 (/ISS) |
Calcium channel regulator activity GO:0005246
Modulates the activity of a calcium channel.
|
2 | P0C605 (/ISO) P0C605 (/ISO) |
Showing 1 to 10 of 15 entries
There are 42 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
9 | Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
9 | Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) |
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
9 | Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) |
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
|
9 | Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) |
Negative regulation of platelet aggregation GO:0090331
Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
|
9 | Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) Q13976 (/IMP) |
Negative regulation of vascular smooth muscle cell proliferation GO:1904706
Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation.
|
9 | Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) |
Negative regulation of vascular associated smooth muscle cell migration GO:1904753
Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration.
|
9 | Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) |
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
|
4 | O77676 (/ISS) P00516 (/ISS) P0C605 (/ISS) P0C605 (/ISS) |
Negative regulation of platelet aggregation GO:0090331
Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
|
4 | O77676 (/ISS) P00516 (/ISS) P0C605 (/ISS) P0C605 (/ISS) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
3 | P0C605 (/IDA) P0C605 (/IDA) Q03043 (/IDA) |
Showing 1 to 10 of 42 entries
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
10 | P00516 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) Q13976 (/TAS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
10 | Q03043 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
9 | Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) Q13976 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | O77676 (/ISS) P00516 (/ISS) P0C605 (/ISS) P0C605 (/ISS) |
Acrosomal vesicle GO:0001669
A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.
|
2 | P0C605 (/ISO) P0C605 (/ISO) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | P0C605 (/ISO) P0C605 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | P0C605 (/ISO) P0C605 (/ISO) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
2 | P0C605 (/IDA) P0C605 (/IDA) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
2 | P0C605 (/ISO) P0C605 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P0C605 (/ISO) P0C605 (/ISO) |
Showing 1 to 10 of 15 entries