The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"iswi atpase
".
FunFam 7: Sodium channel protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Voltage-gated sodium channel activity GO:0005248
Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
3 | Q62968 (/IDA) Q6QIY3 (/IDA) Q9Y5Y9 (/IDA) |
|
Voltage-gated sodium channel activity GO:0005248
Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | Q6QIY3 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q62968 (/IPI) |
|
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
1 | Q9Y5Y9 (/IPI) |
|
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
1 | Q6QIY3 (/ISO) |
Showing 1 to 5 of 5 entries
There are 21 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q62968 (/IDA) Q6QIY3 (/IDA) |
|
Regulation of atrial cardiac muscle cell membrane depolarization GO:0060371
Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte.
|
2 | Q6QIY3 (/IMP) Q9Y5Y9 (/IMP) |
|
Regulation of heart rate GO:0002027
Any process that modulates the frequency or rate of heart contraction.
|
1 | Q9Y5Y9 (/IMP) |
|
Regulation of heart rate GO:0002027
Any process that modulates the frequency or rate of heart contraction.
|
1 | Q6QIY3 (/ISO) |
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q6QIY3 (/ISO) |
|
Sensory perception GO:0007600
The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
|
1 | Q9Y5Y9 (/TAS) |
|
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
|
1 | Q62968 (/IMP) |
|
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
|
1 | Q6QIY3 (/ISO) |
|
Regulation of ion transmembrane transport GO:0034765
Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
|
1 | Q9Y5Y9 (/IDA) |
|
Regulation of ion transmembrane transport GO:0034765
Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
|
1 | Q6QIY3 (/ISO) |
Showing 1 to 10 of 21 entries
There are 14 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Voltage-gated sodium channel complex GO:0001518
A sodium channel in a cell membrane whose opening is governed by the membrane potential.
|
1 | Q9Y5Y9 (/IDA) |
|
Voltage-gated sodium channel complex GO:0001518
A sodium channel in a cell membrane whose opening is governed by the membrane potential.
|
1 | Q6QIY3 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q6QIY3 (/IDA) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q62968 (/IDA) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q6QIY3 (/ISO) |
|
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
|
1 | Q6QIY3 (/IDA) |
|
C-fiber GO:0044299
The axon of a dorsal root ganglion cell that are responsive to pain and temperature. C-fibers are small in diameter (0.2-1.5 um) and unmyelinated.
|
1 | Q6QIY3 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q9Y5Y9 (/HDA) |
|
Clathrin complex GO:0071439
A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold on the vesicle surface.
|
1 | Q62968 (/IDA) |
|
Clathrin complex GO:0071439
A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold on the vesicle surface.
|
1 | Q6QIY3 (/ISO) |
Showing 1 to 10 of 14 entries
