CATH Superfamily 1.20.5.110
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 12: Mitofusin 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 18 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | O95140 (/IPI) Q80U63 (/IPI) Q811U4 (/IPI) Q8IWA4 (/IPI) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
3 | Q7YU24 (/ISS) Q811U4 (/ISS) Q8R4Z9 (/ISS) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | Q8R4Z9 (/IDA) Q8R500 (/IDA) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | Q80U63 (/ISO) Q811U4 (/ISO) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
1 | Q8IWA4 (/IDA) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
1 | Q8IWA4 (/IMP) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
1 | Q811U4 (/ISO) |
|
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
|
1 | Q8R500 (/IMP) |
|
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
|
1 | Q80U63 (/ISO) |
|
Ras GTPase binding GO:0017016
Interacting selectively and non-covalently with any member of the Ras superfamily of monomeric GTPases.
|
1 | Q8R500 (/IDA) |
Showing 1 to 10 of 18 entries
There are 113 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrial fusion GO:0008053
Merging of two or more mitochondria within a cell to form a single compartment.
|
6 | O95140 (/IMP) Q7YU24 (/IMP) Q80U63 (/IMP) Q811U4 (/IMP) Q8IWA4 (/IMP) Q8R500 (/IMP) |
|
Mitochondrion localization GO:0051646
Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
|
5 | Q4R5A0 (/ISS) Q5RAE9 (/ISS) Q80U63 (/ISS) Q811U4 (/ISS) Q8R4Z9 (/ISS) |
|
Protein targeting to mitochondrion GO:0006626
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
|
4 | Q4R5A0 (/ISS) Q5RAE9 (/ISS) Q80U63 (/ISS) Q8R500 (/ISS) |
|
Mitochondrial membrane organization GO:0007006
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.
|
4 | Q4R5A0 (/ISS) Q5RAE9 (/ISS) Q80U63 (/ISS) Q8R500 (/ISS) |
|
Mitochondrial fusion GO:0008053
Merging of two or more mitochondria within a cell to form a single compartment.
|
4 | O95140 (/ISS) Q7YU24 (/ISS) Q8R4Z9 (/ISS) Q8R500 (/ISS) |
|
Negative regulation of smooth muscle cell proliferation GO:0048662
Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.
|
4 | O95140 (/ISS) Q4R5A0 (/ISS) Q5RAE9 (/ISS) Q80U63 (/ISS) |
|
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
|
4 | F7FHF7 (/ISS) O95140 (/ISS) Q6IRL2 (/ISS) Q8R500 (/ISS) |
|
Mitochondrion morphogenesis GO:0070584
The process in which the anatomical structures of a mitochondrion are generated and organized.
|
3 | Q7YU24 (/IMP) Q8R4Z9 (/IMP) Q8R500 (/IMP) |
|
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
|
2 | Q7YU24 (/IMP) Q8R500 (/IMP) |
|
Mitochondrial fusion GO:0008053
Merging of two or more mitochondria within a cell to form a single compartment.
|
2 | Q80U63 (/ISO) Q811U4 (/ISO) |
Showing 1 to 10 of 113 entries
There are 26 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
4 | O95140 (/IDA) Q80U63 (/IDA) Q8IWA4 (/IDA) Q8R500 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | O95140 (/ISS) Q4R5A0 (/ISS) Q5RAE9 (/ISS) Q80U63 (/ISS) |
|
Intrinsic component of mitochondrial outer membrane GO:0031306
The component of the mitochondrial outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
|
4 | O95140 (/ISS) Q4R5A0 (/ISS) Q5RAE9 (/ISS) Q80U63 (/ISS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q80U63 (/HDA) Q811U4 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q80U63 (/ISO) Q811U4 (/ISO) |
|
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
|
2 | Q8R4Z9 (/IDA) Q8R500 (/IDA) |
|
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
|
2 | Q80U63 (/ISO) Q811U4 (/ISO) |
|
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
|
2 | O95140 (/TAS) Q8IWA4 (/TAS) |
|
Integral component of mitochondrial outer membrane GO:0031307
The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q811U4 (/ISS) Q8R4Z9 (/ISS) |
|
Outer mitochondrial membrane protein complex GO:0098799
Any protein complex that is part of the outer mitochondrial membrane.
|
2 | Q811U4 (/ISS) Q8R4Z9 (/ISS) |
Showing 1 to 10 of 26 entries
