The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cytochrome c oxidase-like, subunit I domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Cytochrome c oxidase, cbb3-type, subunit I

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytochrome-c oxidase activity GO:0004129
Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
13 Q9I3G0 (/IMP) Q9I3G0 (/IMP) Q9I3G0 (/IMP) Q9I3G0 (/IMP) Q9I3G0 (/IMP) Q9I3G0 (/IMP) Q9I3G0 (/IMP) Q9I3G3 (/IMP) Q9I3G3 (/IMP) Q9I3G3 (/IMP)
(3 more)
Cytochrome-c oxidase activity GO:0004129
Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
8 Q9KS19 (/ISS) Q9KS19 (/ISS) Q9KS19 (/ISS) Q9KS19 (/ISS) Q9KS19 (/ISS) Q9KS19 (/ISS) Q9KS19 (/ISS) Q9KS19 (/ISS)
Cytochrome-c oxidase activity GO:0004129
Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
2 D9IA43 (/IC) D9IA43 (/IC)
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
2 D9IA43 (/IDA) D9IA43 (/IDA)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
2 D9IA43 (/IDA) D9IA43 (/IDA)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.
2 D9IA43 (/IC) D9IA43 (/IC)
Oxygen binding GO:0019825
Interacting selectively and non-covalently with oxygen (O2).
2 D9IA43 (/IC) D9IA43 (/IC)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
2 D9IA43 (/IDA) D9IA43 (/IDA)
Electron transporter, transferring electrons within cytochrome c oxidase complex activity GO:0045154
Enables the directed movement of electrons within the cytochrome c oxidase complex.
2 D9IA43 (/IC) D9IA43 (/IC)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Oxidative phosphorylation GO:0006119
The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
2 D9IA43 (/IC) D9IA43 (/IC)
Electron transport coupled proton transport GO:0015990
The transport of protons against an electrochemical gradient, using energy from electron transport.
2 D9IA43 (/IC) D9IA43 (/IC)
Aerobic respiration, using ferrous ions as electron donor GO:0019411
The metabolic process in which ferrous ions (Fe2+) are oxidized to ferric ions (Fe3+) to generate energy, coupled to the reduction of carbon dioxide.
2 D9IA43 (/IC) D9IA43 (/IC)
Aerobic electron transport chain GO:0019646
A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient.
2 D9IA43 (/IC) D9IA43 (/IC)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
2 D9IA43 (/IC) D9IA43 (/IC)
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
2 D9IA43 (/IC) D9IA43 (/IC)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 D9IA43 (/ISS) D9IA43 (/ISS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 D9IA43 (/ISS) D9IA43 (/ISS)
Cytochrome complex GO:0070069
A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.
2 D9IA43 (/IDA) D9IA43 (/IDA)
Cytochrome complex GO:0070069
A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.
2 D9IA43 (/IPI) D9IA43 (/IPI)
Plasma membrane respirasome GO:0070470
A respiratory chain located in the plasma membrane of a cell; made up of the protein complexes that form the electron transport system (the respiratory chain), associated with the plasma membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.
2 D9IA43 (/IC) D9IA43 (/IC)
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