The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Cytochrome c oxidase-like, subunit I domain
".
FunFam 1: Cytochrome c oxidase subunit 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytochrome-c oxidase activity GO:0004129
Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
|
9 | E2JDJ7 (/IDA) E2JDJ7 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | O21042 (/IPI) P00395 (/IPI) P00395 (/IPI) P00395 (/IPI) |
Cytochrome-c oxidase activity GO:0004129
Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
|
2 | P00399 (/IMP) P00399 (/IMP) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Positive regulation of vasoconstriction GO:0045907
Any process that activates or increases the frequency, rate or extent of vasoconstriction.
|
8 | Q1WEZ6 (/IMP) Q71KK5 (/IMP) Q71KK5 (/IMP) Q71KK5 (/IMP) Q71KK5 (/IMP) Q71KK5 (/IMP) Q71KK5 (/IMP) Q71KK5 (/IMP) |
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
7 | P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) |
Mitochondrial electron transport, cytochrome c to oxygen GO:0006123
The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV.
|
3 | P00395 (/TAS) P00395 (/TAS) P00395 (/TAS) |
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
|
3 | Q9MIY8 (/IEP) Q9MIY8 (/IEP) Q9MIY8 (/IEP) |
Response to methylmercury GO:0051597
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.
|
3 | Q9MIY8 (/IDA) Q9MIY8 (/IDA) Q9MIY8 (/IDA) |
Mitochondrial electron transport, cytochrome c to oxygen GO:0006123
The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV.
|
2 | P00399 (/IMP) P00399 (/IMP) |
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
2 | P05503 (/IDA) P05503 (/IDA) |
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
|
2 | P05503 (/IEP) P05503 (/IEP) |
Cerebellum development GO:0021549
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
|
2 | P05503 (/IEP) P05503 (/IEP) |
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
2 | P05503 (/IEP) P05503 (/IEP) |
Response to electrical stimulus GO:0051602
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.
|
2 | P05503 (/IEP) P05503 (/IEP) |
There are 16 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Respiratory chain complex IV GO:0045277
A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
|
235 |
O03167 (/ISS)
O03198 (/ISS)
O21079 (/ISS)
O21327 (/ISS)
O21399 (/ISS)
O78681 (/ISS)
O78681 (/ISS)
O78681 (/ISS)
O78681 (/ISS)
O78681 (/ISS)
(225 more) |
Respiratory chain complex IV GO:0045277
A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
|
12 |
P00395 (/IDA)
P00395 (/IDA)
P00395 (/IDA)
P00396 (/IDA)
P00396 (/IDA)
P00396 (/IDA)
P00396 (/IDA)
P00396 (/IDA)
P00396 (/IDA)
P00396 (/IDA)
(2 more) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
10 | P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P05503 (/IDA) P05503 (/IDA) P18943 (/IDA) |
Mitochondrial respiratory chain complex IV GO:0005751
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
|
10 | P00395 (/IDA) P00395 (/IDA) P00395 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
7 | P00397 (/HDA) P00397 (/HDA) P00397 (/HDA) P00397 (/HDA) P00397 (/HDA) P00397 (/HDA) P00397 (/HDA) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
7 | P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) |
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
7 | P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) P00397 (/IDA) |
Mitochondrial respiratory chain complex III GO:0005750
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1.
|
7 | P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) |
Mitochondrial respiratory chain complex IV GO:0005751
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
|
7 | P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) |
Respiratory chain complex IV GO:0045277
A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
|
7 | P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) P00397 (/ISO) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
6 | P14578 (/ISS) P14578 (/ISS) P14578 (/ISS) P14578 (/ISS) P14578 (/ISS) P14578 (/ISS) |
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
3 | P00395 (/TAS) P00395 (/TAS) P00395 (/TAS) |
Mitochondrial respiratory chain complex III GO:0005750
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1.
|
3 | P00395 (/IDA) P00395 (/IDA) P00395 (/IDA) |
Mitochondrial respiratory chain complex IV GO:0005751
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
|
3 | P00395 (/IMP) P00395 (/IMP) P00395 (/IMP) |
Respiratory chain complex IV GO:0045277
A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
|
2 | P00399 (/IC) P00399 (/IC) |
Respiratory chain complex IV GO:0045277
A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
|
2 | P00399 (/IMP) P00399 (/IMP) |