The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
ABC transporter type 1, transmembrane domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: Lipid A export ATP-binding/permease protein MsbA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
303 P60752 (/IPI) P60752 (/IPI) P60752 (/IPI) P60752 (/IPI) P60752 (/IPI) P60752 (/IPI) P60752 (/IPI) P60752 (/IPI) P60752 (/IPI) P60752 (/IPI)
(293 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
108 P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA)
(98 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
108 P60752 (/ISM) P60752 (/ISM) P60752 (/ISM) P60752 (/ISM) P60752 (/ISM) P60752 (/ISM) P60752 (/ISM) P60752 (/ISM) P60752 (/ISM) P60752 (/ISM)
(98 more)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
108 P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA)
(98 more)
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
108 P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA)
(98 more)
ATPase-coupled xenobiotic transmembrane transporter activity GO:0008559
Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out).
108 P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA)
(98 more)
Lipopolysaccharide floppase activity GO:0015437
Enables the transfer of a lipopolysaccharide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.
108 P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA)
(98 more)
ATPase-coupled lipid transmembrane transporter activity GO:0034040
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out).
108 P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA)
(98 more)
Lipid transporter activity GO:0005319
Enables the directed movement of lipids into, out of or within a cell, or between cells.
7 Q9KQW9 (/ISS) Q9KQW9 (/ISS) Q9KQW9 (/ISS) Q9KQW9 (/ISS) Q9KQW9 (/ISS) Q9KQW9 (/ISS) Q9KQW9 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lipopolysaccharide transport GO:0015920
The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.
108 P60752 (/IMP) P60752 (/IMP) P60752 (/IMP) P60752 (/IMP) P60752 (/IMP) P60752 (/IMP) P60752 (/IMP) P60752 (/IMP) P60752 (/IMP) P60752 (/IMP)
(98 more)
Lipid translocation GO:0034204
The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
108 P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA)
(98 more)
Lipid transport GO:0006869
The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
7 Q9KQW9 (/ISS) Q9KQW9 (/ISS) Q9KQW9 (/ISS) Q9KQW9 (/ISS) Q9KQW9 (/ISS) Q9KQW9 (/ISS) Q9KQW9 (/ISS)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
108 P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA)
(98 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
108 P60752 (/ISM) P60752 (/ISM) P60752 (/ISM) P60752 (/ISM) P60752 (/ISM) P60752 (/ISM) P60752 (/ISM) P60752 (/ISM) P60752 (/ISM) P60752 (/ISM)
(98 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
108 P60752 (/HDA) P60752 (/HDA) P60752 (/HDA) P60752 (/HDA) P60752 (/HDA) P60752 (/HDA) P60752 (/HDA) P60752 (/HDA) P60752 (/HDA) P60752 (/HDA)
(98 more)
ATP-binding cassette (ABC) transporter complex GO:0043190
A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
108 P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA) P60752 (/IDA)
(98 more)
ATP-binding cassette (ABC) transporter complex GO:0043190
A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
108 P60752 (/RCA) P60752 (/RCA) P60752 (/RCA) P60752 (/RCA) P60752 (/RCA) P60752 (/RCA) P60752 (/RCA) P60752 (/RCA) P60752 (/RCA) P60752 (/RCA)
(98 more)
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