The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
ABC transporter type 1, transmembrane domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13: ABC transporter C family member 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATPase-coupled transmembrane transporter activity GO:0042626
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
4 Q42093 (/ISS) Q9C8G9 (/ISS) Q9C8G9 (/ISS) Q9C8H1 (/ISS)
(+)-abscisic acid D-glucopyranosyl ester transmembrane transporter activity GO:1902417
Enables the transfer of (+)-abscisic acid D-glucopyranosyl ester from one side of a membrane to the other.
3 Q42093 (/IDA) Q9C8G9 (/IDA) Q9C8G9 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q9C8G9 (/IPI) Q9C8G9 (/IPI)
Cadmium ion transmembrane transporter activity GO:0015086
Enables the transfer of cadmium (Cd) ions from one side of a membrane to the other.
2 P14772 (/IDA) P14772 (/IDA)
Bilirubin transmembrane transporter activity GO:0015127
Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile.
2 P14772 (/IGI) P14772 (/IGI)
Bilirubin transmembrane transporter activity GO:0015127
Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile.
2 P14772 (/IMP) P14772 (/IMP)
ATPase-coupled arsenite transmembrane transporter activity GO:0015446
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out).
2 Q9C8G9 (/IDA) Q9C8G9 (/IDA)
ATPase-coupled transmembrane transporter activity GO:0042626
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
1 Q42093 (/IDA)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
(+)-abscisic acid D-glucopyranosyl ester transmembrane transport GO:1902418
The process in which (+)-abscisic acid D-glucopyranosyl este is transported across a membrane.
3 Q42093 (/IDA) Q9C8G9 (/IDA) Q9C8G9 (/IDA)
Cadmium ion transport GO:0015691
The directed movement of cadmium (Cd) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P14772 (/IDA) P14772 (/IDA)
Arsenite transport GO:0015700
The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q9C8G9 (/IDA) Q9C8G9 (/IDA)
Bilirubin transport GO:0015723
The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P14772 (/IGI) P14772 (/IGI)
Bilirubin transport GO:0015723
The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P14772 (/IMP) P14772 (/IMP)
Vacuole fusion, non-autophagic GO:0042144
The fusion of two vacuole membranes to form a single vacuole.
2 P14772 (/IMP) P14772 (/IMP)
Response to arsenic-containing substance GO:0046685
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
2 Q9C8G9 (/IMP) Q9C8G9 (/IMP)
Phytochelatin 2 import into vacuole GO:0036246
The directed movement of phytochelatin 2 (PC2) into the vacuole. Phytochelatin 2 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=2, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.
1 Q9P7V2 (/IMP)
Glutathione transmembrane import into vacuole GO:0071996
The directed movement of glutathione into the vacuole across the vacuolar membrane.
1 Q9P7V2 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plant-type vacuole GO:0000325
A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana.
3 Q42093 (/IDA) Q9C8G9 (/IDA) Q9C8G9 (/IDA)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
3 Q42093 (/IDA) Q9C8G9 (/IDA) Q9C8G9 (/IDA)
Vacuolar membrane GO:0005774
The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
3 Q42093 (/IDA) Q9C8G9 (/IDA) Q9C8G9 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
3 P14772 (/HDA) P14772 (/HDA) Q92337 (/HDA)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
2 P14772 (/IDA) P14772 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
2 Q9C8G9 (/IDA) Q9C8G9 (/IDA)
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
1 Q9P7V2 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q92337 (/IDA)
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