The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cation efflux protein transmembrane domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 18: transmembrane protein 163

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
7 A6QQX9 (/ISS) A6QQX9 (/ISS) Q6GLN7 (/ISS) Q6GLN7 (/ISS) Q8C996 (/ISS) Q8TC26 (/ISS) Q8TC26 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q8C996 (/IPI)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 A9CMA6 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 Q8C996 (/ISO)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Zinc ion import into synaptic vesicle GO:0099180
The directed movement of Zn2+ ions from the cytoplasm into the lumen of a cytoplasmic vesicle.
1 A9CMA6 (/IDA)
Zinc ion import into synaptic vesicle GO:0099180
The directed movement of Zn2+ ions from the cytoplasm into the lumen of a cytoplasmic vesicle.
1 A9CMA6 (/IMP)
Zinc ion import into synaptic vesicle GO:0099180
The directed movement of Zn2+ ions from the cytoplasm into the lumen of a cytoplasmic vesicle.
1 Q8C996 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Early endosome membrane GO:0031901
The lipid bilayer surrounding an early endosome.
7 A6QQX9 (/ISS) A6QQX9 (/ISS) Q6GLN7 (/ISS) Q6GLN7 (/ISS) Q8C996 (/ISS) Q8TC26 (/ISS) Q8TC26 (/ISS)
Integral component of synaptic vesicle membrane GO:0030285
The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
6 A6QQX9 (/ISS) A6QQX9 (/ISS) Q6GLN7 (/ISS) Q6GLN7 (/ISS) Q8TC26 (/ISS) Q8TC26 (/ISS)
Integral component of synaptic vesicle membrane GO:0030285
The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 A9CMA6 (/IDA) Q8C996 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q8C996 (/EXP)
Integral component of synaptic vesicle membrane GO:0030285
The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q8C996 (/ISO)
Early endosome membrane GO:0031901
The lipid bilayer surrounding an early endosome.
1 A9CMA6 (/IDA)
Early endosome membrane GO:0031901
The lipid bilayer surrounding an early endosome.
1 Q8C996 (/ISO)
Intracellular vesicle GO:0097708
Any vesicle that is part of the intracellular region.
1 Q8C996 (/EXP)
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