The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Cation efflux protein transmembrane domain
".
FunFam 10: Putative zinc transporter 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Zinc ion transmembrane transporter activity GO:0005385
Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.
|
2 | M9PEG6 (/IC) Q7K3K5 (/IC) |
Zinc ion transmembrane transporter activity GO:0005385
Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Calcium channel inhibitor activity GO:0019855
Stops, prevents, or reduces the activity of a calcium channel.
|
2 | Q60738 (/IDA) Q60738 (/IDA) |
Calcium channel inhibitor activity GO:0019855
Stops, prevents, or reduces the activity of a calcium channel.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Zinc ion transmembrane transporter activity GO:0005385
Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.
|
1 | Q62720 (/IDA) |
Zinc ion transmembrane transporter activity GO:0005385
Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.
|
1 | Q62720 (/IMP) |
Zinc ion transmembrane transporter activity GO:0005385
Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.
|
1 | Q6P3M0 (/ISS) |
Zinc ion transmembrane transporter activity GO:0005385
Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.
|
1 | Q9Y6M5 (/TAS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9Y6M5 (/IPI) |
Calcium channel inhibitor activity GO:0019855
Stops, prevents, or reduces the activity of a calcium channel.
|
1 | Q62720 (/IMP) |
Calcium channel inhibitor activity GO:0019855
Stops, prevents, or reduces the activity of a calcium channel.
|
1 | Q9Y6M5 (/ISS) |
Zinc efflux transmembrane transporter activity GO:0022883
Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane.
|
1 | M9PEG6 (/IGI) |
There are 29 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cellular zinc ion homeostasis GO:0006882
Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell.
|
4 | M9PEG6 (/IMP) Q60738 (/IMP) Q60738 (/IMP) Q7K3K5 (/IMP) |
Zinc ion transport GO:0006829
The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | Q60738 (/IDA) Q60738 (/IDA) Q62720 (/IDA) |
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
|
2 | Q60738 (/IMP) Q60738 (/IMP) |
Zinc ion transport GO:0006829
The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Zinc ion transport GO:0006829
The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q6P3M0 (/ISS) Q9Y6M5 (/ISS) |
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
|
2 | Q60738 (/IDA) Q60738 (/IDA) |
Cellular zinc ion homeostasis GO:0006882
Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell.
|
2 | Q60738 (/IDA) Q60738 (/IDA) |
Detoxification of zinc ion GO:0010312
Any process that reduces or removes the toxicity of zinc ion. These include transport of zinc away from sensitive areas and to compartments or complexes whose purpose is sequestration of zinc ion.
|
2 | M9PEG6 (/IMP) Q7K3K5 (/IMP) |
Negative regulation of neurotransmitter secretion GO:0046929
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Zinc ion homeostasis GO:0055069
Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell.
|
2 | M9PEG6 (/IGI) Q7K3K5 (/IGI) |
Calcium ion import GO:0070509
The directed movement of calcium ions into a cell or organelle.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Cadmium ion transmembrane transport GO:0070574
A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Zinc ion transmembrane transport GO:0071577
A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
2 | M9PEG6 (/IGI) Q7K3K5 (/IGI) |
Negative regulation of zinc ion transmembrane import GO:0071584
Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import.
|
2 | Q60738 (/IDA) Q60738 (/IDA) |
Detoxification of cadmium ion GO:0071585
Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Negative regulation of calcium ion import GO:0090281
Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
|
2 | Q60738 (/IDA) Q60738 (/IDA) |
Zinc ion transport GO:0006829
The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q62720 (/IMP) |
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
|
1 | Q9Y6M5 (/ISS) |
Cellular zinc ion homeostasis GO:0006882
Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell.
|
1 | Q9Y6M5 (/ISS) |
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
|
1 | Q6P3M0 (/IDA) |
Negative regulation of neurotransmitter secretion GO:0046929
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.
|
1 | Q62720 (/IMP) |
Negative regulation of neurotransmitter secretion GO:0046929
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.
|
1 | Q9Y6M5 (/ISS) |
Zinc ion homeostasis GO:0055069
Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell.
|
1 | M9PEG6 (/IMP) |
Calcium ion import GO:0070509
The directed movement of calcium ions into a cell or organelle.
|
1 | Q62720 (/IMP) |
Cadmium ion transmembrane transport GO:0070574
A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | Q62720 (/IMP) |
Cadmium ion transmembrane transport GO:0070574
A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | Q9Y6M5 (/ISS) |
Negative regulation of zinc ion transmembrane import GO:0071584
Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import.
|
1 | Q9Y6M5 (/ISS) |
Detoxification of cadmium ion GO:0071585
Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion.
|
1 | Q62720 (/IMP) |
Negative regulation of calcium ion import GO:0090281
Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
|
1 | Q9Y6M5 (/ISS) |
There are 22 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | M9PEG6 (/IDA) Q62720 (/IDA) Q7K3K5 (/IDA) Q9Y6M5 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
2 | M9PEG6 (/IDA) Q7K3K5 (/IDA) |
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
2 | M9PEG6 (/IDA) Q7K3K5 (/IDA) |
T-tubule GO:0030315
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Schaffer collateral - CA1 synapse GO:0098685
A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Integral component of postsynaptic density membrane GO:0099061
The component of the postsynaptic density membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q60738 (/ISO) Q60738 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9Y6M5 (/IDA) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | Q9Y6M5 (/IDA) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
1 | Q9Y6M5 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9Y6M5 (/TAS) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q62720 (/IDA) |
T-tubule GO:0030315
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
|
1 | Q62720 (/IDA) |
T-tubule GO:0030315
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
|
1 | Q9Y6M5 (/ISS) |
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
1 | Q9Y6M5 (/IDA) |
Schaffer collateral - CA1 synapse GO:0098685
A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell.
|
1 | Q62720 (/IDA) |
Integral component of postsynaptic density membrane GO:0099061
The component of the postsynaptic density membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q62720 (/IDA) |