The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"I/LWEQ domain
".
FunFam 3: Transmembrane protein 98
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | Q91X86 (/IPI) Q91X86 (/IPI) Q91X86 (/IPI) Q91X86 (/IPI) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Negative regulation of myelination GO:0031642
Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
|
22 |
Q2HJB9 (/ISS)
Q6AYS5 (/ISS)
Q6AYS5 (/ISS)
Q6AYS5 (/ISS)
Q6AYS5 (/ISS)
Q6INX1 (/ISS)
Q6INX1 (/ISS)
Q9Y2Y6 (/ISS)
Q9Y2Y6 (/ISS)
Q9Y2Y6 (/ISS)
(12 more) |
Negative regulation of oligodendrocyte differentiation GO:0048715
Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation.
|
22 |
Q2HJB9 (/ISS)
Q6AYS5 (/ISS)
Q6AYS5 (/ISS)
Q6AYS5 (/ISS)
Q6AYS5 (/ISS)
Q6INX1 (/ISS)
Q6INX1 (/ISS)
Q9Y2Y6 (/ISS)
Q9Y2Y6 (/ISS)
Q9Y2Y6 (/ISS)
(12 more) |
T-helper 1 cell differentiation GO:0045063
The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
|
20 |
Q2HJB9 (/ISS)
Q6AYS5 (/ISS)
Q6AYS5 (/ISS)
Q6AYS5 (/ISS)
Q6AYS5 (/ISS)
Q9Y2Y6 (/ISS)
Q9Y2Y6 (/ISS)
Q9Y2Y6 (/ISS)
Q9Y2Y6 (/ISS)
Q9Y2Y6 (/ISS)
(10 more) |
Negative regulation of protein processing GO:0010955
Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.
|
7 | Q2HJB9 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6INX1 (/ISS) Q6INX1 (/ISS) |
Negative regulation of protein localization to nucleus GO:1900181
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus.
|
7 | Q2HJB9 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6INX1 (/ISS) Q6INX1 (/ISS) |
Negative regulation of protein processing GO:0010955
Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.
|
4 | Q91X86 (/IDA) Q91X86 (/IDA) Q91X86 (/IDA) Q91X86 (/IDA) |
Negative regulation of myelination GO:0031642
Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
|
4 | Q91X86 (/IMP) Q91X86 (/IMP) Q91X86 (/IMP) Q91X86 (/IMP) |
T-helper 1 cell differentiation GO:0045063
The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
|
4 | Q91X86 (/IDA) Q91X86 (/IDA) Q91X86 (/IDA) Q91X86 (/IDA) |
Negative regulation of oligodendrocyte differentiation GO:0048715
Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation.
|
4 | Q91X86 (/IMP) Q91X86 (/IMP) Q91X86 (/IMP) Q91X86 (/IMP) |
Negative regulation of protein localization to nucleus GO:1900181
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus.
|
4 | Q91X86 (/IDA) Q91X86 (/IDA) Q91X86 (/IDA) Q91X86 (/IDA) |
There are 13 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
19 |
Q91X86 (/IDA)
Q91X86 (/IDA)
Q91X86 (/IDA)
Q91X86 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
(9 more) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
15 |
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
(5 more) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
15 |
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
(5 more) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
15 |
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
Q9Y2Y6 (/IDA)
(5 more) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
9 | Q2HJB9 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q91X86 (/ISS) Q91X86 (/ISS) Q91X86 (/ISS) Q91X86 (/ISS) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
9 | Q2HJB9 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q91X86 (/ISS) Q91X86 (/ISS) Q91X86 (/ISS) Q91X86 (/ISS) |
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
7 | Q2HJB9 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6INX1 (/ISS) Q6INX1 (/ISS) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
5 | Q2HJB9 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) Q6AYS5 (/ISS) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
4 | Q91X86 (/ISO) Q91X86 (/ISO) Q91X86 (/ISO) Q91X86 (/ISO) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
4 | Q91X86 (/ISO) Q91X86 (/ISO) Q91X86 (/ISO) Q91X86 (/ISO) |
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
4 | Q91X86 (/IDA) Q91X86 (/IDA) Q91X86 (/IDA) Q91X86 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | Q91X86 (/ISO) Q91X86 (/ISO) Q91X86 (/ISO) Q91X86 (/ISO) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
4 | Q91X86 (/ISO) Q91X86 (/ISO) Q91X86 (/ISO) Q91X86 (/ISO) |