The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"I/LWEQ domain
".
FunFam 1: Talin 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 16 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
10 | M9PBW9 (/IPI) M9PEJ8 (/IPI) P26039 (/IPI) P54939 (/IPI) Q54K81 (/IPI) Q71LX4 (/IPI) Q960C2 (/IPI) Q9VSL8 (/IPI) Q9Y490 (/IPI) Q9Y4G6 (/IPI) |
|
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
6 | G3V852 (/IPI) M9PBW9 (/IPI) M9PEJ8 (/IPI) Q960C2 (/IPI) Q9VSL8 (/IPI) Q9Y490 (/IPI) |
|
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
|
1 | P26039 (/IMP) |
|
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
1 | Q9Y4G6 (/NAS) |
|
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
1 | P26039 (/IMP) |
|
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
1 | P26039 (/ISO) |
|
Structural molecule activity GO:0005198
The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.
|
1 | Q9Y4G6 (/NAS) |
|
Structural constituent of cytoskeleton GO:0005200
The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
|
1 | Q9Y490 (/NAS) |
|
Phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547
Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
|
1 | Q54K81 (/IDA) |
|
Vinculin binding GO:0017166
Interacting selectively and non-covalently with vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane.
|
1 | Q9Y490 (/IPI) |
Showing 1 to 10 of 16 entries
There are 44 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sarcomere organization GO:0045214
The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
|
6 | A0A0R4IDZ8 (/IMP) M9PBW9 (/IMP) M9PEJ8 (/IMP) Q5U7N6 (/IMP) Q960C2 (/IMP) Q9VSL8 (/IMP) |
|
Cytoskeletal anchoring at plasma membrane GO:0007016
A cytoskeleton organization process that directly or indirectly links cytoskeletal filaments to the plasma membrane.
|
4 | M9PBW9 (/ISS) M9PEJ8 (/ISS) Q960C2 (/ISS) Q9VSL8 (/ISS) |
|
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
4 | M9PBW9 (/IMP) M9PEJ8 (/IMP) Q960C2 (/IMP) Q9VSL8 (/IMP) |
|
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
4 | M9PBW9 (/TAS) M9PEJ8 (/TAS) Q960C2 (/TAS) Q9VSL8 (/TAS) |
|
Border follicle cell migration GO:0007298
The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.
|
4 | M9PBW9 (/IMP) M9PEJ8 (/IMP) Q960C2 (/IMP) Q9VSL8 (/IMP) |
|
Germ-band shortening GO:0007390
The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo.
|
4 | M9PBW9 (/IMP) M9PEJ8 (/IMP) Q960C2 (/IMP) Q9VSL8 (/IMP) |
|
Apposition of dorsal and ventral imaginal disc-derived wing surfaces GO:0007475
The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing.
|
4 | M9PBW9 (/IMP) M9PEJ8 (/IMP) Q960C2 (/IMP) Q9VSL8 (/IMP) |
|
Larval somatic muscle development GO:0007526
The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure.
|
4 | M9PBW9 (/IMP) M9PEJ8 (/IMP) Q960C2 (/IMP) Q9VSL8 (/IMP) |
|
Muscle attachment GO:0016203
The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).
|
4 | M9PBW9 (/IMP) M9PEJ8 (/IMP) Q960C2 (/IMP) Q9VSL8 (/IMP) |
|
Cell adhesion mediated by integrin GO:0033627
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.
|
4 | M9PBW9 (/IMP) M9PEJ8 (/IMP) Q960C2 (/IMP) Q9VSL8 (/IMP) |
Showing 1 to 10 of 44 entries
There are 26 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
6 | M9PBW9 (/IDA) M9PEJ8 (/IDA) P26039 (/IDA) P54939 (/IDA) Q960C2 (/IDA) Q9VSL8 (/IDA) |
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
6 | M9PBW9 (/ISS) M9PEJ8 (/ISS) P26039 (/ISS) Q960C2 (/ISS) Q9VSL8 (/ISS) Q9Y490 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | G5EGK1 (/IDA) Q1ZXE9 (/IDA) Q54K81 (/IDA) |
|
Ruffle GO:0001726
Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
|
2 | P26039 (/ISS) Q9Y490 (/ISS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P54939 (/TAS) Q9Y490 (/TAS) |
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
2 | Q9Y490 (/HDA) Q9Y4G6 (/HDA) |
|
M band GO:0031430
The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines.
|
2 | G4S9F5 (/IDA) G5EGK1 (/IDA) |
|
Striated muscle dense body GO:0055120
A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere.
|
2 | G4S9F5 (/IDA) G5EGK1 (/IDA) |
|
Ruffle GO:0001726
Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
|
1 | P54939 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | Q9Y490 (/TAS) |
Showing 1 to 10 of 26 entries
