CATH Superfamily 1.20.140.20
Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain
".
FunFam 2: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
6 | O14874 (/ISS) O14874 (/ISS) O55028 (/ISS) O55028 (/ISS) Q2KJG8 (/ISS) Q2KJG8 (/ISS) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
6 | O14874 (/ISS) O14874 (/ISS) O55028 (/ISS) O55028 (/ISS) Q2KJG8 (/ISS) Q2KJG8 (/ISS) |
|
[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity GO:0047323
Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate.
|
3 | O14874 (/TAS) O14874 (/TAS) Q00972 (/TAS) |
|
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
2 | O55028 (/IDA) O55028 (/IDA) |
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
2 | O55028 (/ISO) O55028 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O14874 (/IPI) O14874 (/IPI) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
2 | O55028 (/ISO) O55028 (/ISO) |
|
Kinase activity GO:0016301
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
|
2 | O14874 (/TAS) O14874 (/TAS) |
|
[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity GO:0047323
Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate.
|
2 | O55028 (/ISO) O55028 (/ISO) |
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
1 | Q00972 (/IDA) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q00972 (/IDA) |
|
[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity GO:0047323
Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate.
|
1 | Q00972 (/IMP) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Branched-chain amino acid catabolic process GO:0009083
The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
|
6 | O14874 (/ISS) O14874 (/ISS) O55028 (/ISS) O55028 (/ISS) Q2KJG8 (/ISS) Q2KJG8 (/ISS) |
|
Phosphorylation GO:0016310
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
|
6 | O14874 (/ISS) O14874 (/ISS) O55028 (/ISS) O55028 (/ISS) Q2KJG8 (/ISS) Q2KJG8 (/ISS) |
|
Branched-chain amino acid catabolic process GO:0009083
The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
|
3 | O14874 (/TAS) O14874 (/TAS) Q00972 (/TAS) |
|
Cellular amino acid catabolic process GO:0009063
The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.
|
2 | O14874 (/NAS) O14874 (/NAS) |
|
Branched-chain amino acid catabolic process GO:0009083
The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
|
2 | O55028 (/ISO) O55028 (/ISO) |
|
Phosphorylation GO:0016310
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
|
2 | O55028 (/ISO) O55028 (/ISO) |
|
Phosphorylation GO:0016310
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
|
2 | O14874 (/TAS) O14874 (/TAS) |
|
Branched-chain amino acid catabolic process GO:0009083
The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
|
1 | Q00972 (/IDA) |
|
Phosphorylation GO:0016310
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
|
1 | Q00972 (/IDA) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrial alpha-ketoglutarate dehydrogenase complex GO:0005947
Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity.
|
6 | O14874 (/ISS) O14874 (/ISS) O55028 (/ISS) O55028 (/ISS) Q2KJG8 (/ISS) Q2KJG8 (/ISS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
4 | O14874 (/HDA) O14874 (/HDA) O55028 (/HDA) O55028 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
4 | A0A024QZA9 (/IDA) A0A024QZA9 (/IDA) O14874 (/IDA) O14874 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
3 | O14874 (/TAS) O14874 (/TAS) Q00972 (/TAS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | O55028 (/ISO) O55028 (/ISO) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
2 | O14874 (/TAS) O14874 (/TAS) |
|
Mitochondrial alpha-ketoglutarate dehydrogenase complex GO:0005947
Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity.
|
2 | O55028 (/ISO) O55028 (/ISO) |
|
Mitochondrial alpha-ketoglutarate dehydrogenase complex GO:0005947
Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity.
|
2 | O14874 (/TAS) O14874 (/TAS) |
|
Mitochondrial alpha-ketoglutarate dehydrogenase complex GO:0005947
Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity.
|
1 | Q00972 (/IDA) |
