The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: uncharacterized protein C16orf52 homolog

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
65 Q0D289 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS)
(55 more)
Regulation of neuron differentiation GO:0045664
Any process that modulates the frequency, rate or extent of neuron differentiation.
65 Q0D289 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS)
(55 more)
Negative regulation of smoothened signaling pathway GO:0045879
Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling.
65 Q0D289 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS)
(55 more)
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
64 Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP)
(54 more)
Regulation of neuron differentiation GO:0045664
Any process that modulates the frequency, rate or extent of neuron differentiation.
64 Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP)
(54 more)
Negative regulation of smoothened signaling pathway GO:0045879
Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling.
64 Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP) Q8C784 (/IMP)
(54 more)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
65 Q0D289 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS)
(55 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
65 Q0D289 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS)
(55 more)
Ciliary membrane GO:0060170
The portion of the plasma membrane surrounding a cilium.
65 Q0D289 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS) Q8NHV5 (/ISS)
(55 more)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
64 Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA)
(54 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
64 Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA)
(54 more)
Ciliary membrane GO:0060170
The portion of the plasma membrane surrounding a cilium.
64 Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA) Q8C784 (/IDA)
(54 more)
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