CATH Superfamily 1.20.140.150
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 23: Epithelial membrane protein 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
3 | O88662 (/IPI) O88662 (/IPI) P54851 (/IPI) |
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P54851 (/IPI) |
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
|
1 | P54851 (/IPI) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | P54851 (/IPI) |
There are 67 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
8 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) F1QIK8 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Regulation of glomerular filtration GO:0003093
Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule.
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Cell-matrix adhesion GO:0007160
The binding of a cell to the extracellular matrix via adhesion molecules.
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Cell death GO:0008219
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Regulation of endothelial cell migration GO:0010594
Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Bleb assembly GO:0032060
The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Activation of protein kinase activity GO:0032147
Any process that initiates the activity of an inactive protein kinase.
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Protein localization to cell surface GO:0034394
A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Blood vessel endothelial cell migration GO:0043534
The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis.
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Regulation of kinase activity GO:0043549
Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Regulation of angiogenesis GO:0045765
Any process that modulates the frequency, rate or extent of angiogenesis.
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Actin-mediated cell contraction GO:0070252
The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Regulation of vasculogenesis GO:2001212
Any process that modulates the frequency, rate or extent of vasculogenesis.
|
7 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) O88662 (/ISS) O88662 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Membrane raft assembly GO:0001765
The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes.
|
6 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) P54851 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
T cell mediated cytotoxicity GO:0001913
The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
|
6 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) P54851 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Early endosome to late endosome transport GO:0045022
The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
|
6 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) P54851 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
|
6 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) P54851 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Embryo implantation GO:0007566
Attachment of the blastocyst to the uterine lining.
|
5 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Embryo implantation GO:0007566
Attachment of the blastocyst to the uterine lining.
|
3 | O88662 (/IMP) O88662 (/IMP) P54851 (/IMP) |
Membrane raft assembly GO:0001765
The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes.
|
2 | O88662 (/IDA) O88662 (/IDA) |
T cell mediated cytotoxicity GO:0001913
The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
|
2 | O88662 (/IDA) O88662 (/IDA) |
Regulation of cell-matrix adhesion GO:0001952
Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix.
|
2 | O88662 (/IDA) O88662 (/IDA) |
Positive regulation of cell-matrix adhesion GO:0001954
Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Regulation of glomerular filtration GO:0003093
Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Cell-matrix adhesion GO:0007160
The binding of a cell to the extracellular matrix via adhesion molecules.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Embryo implantation GO:0007566
Attachment of the blastocyst to the uterine lining.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Cell death GO:0008219
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
|
2 | O88662 (/ISO) O88662 (/ISO) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Regulation of endothelial cell migration GO:0010594
Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Bleb assembly GO:0032060
The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Activation of protein kinase activity GO:0032147
Any process that initiates the activity of an inactive protein kinase.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Protein localization to cell surface GO:0034394
A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Blood vessel endothelial cell migration GO:0043534
The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Regulation of kinase activity GO:0043549
Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Early endosome to late endosome transport GO:0045022
The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
|
2 | O88662 (/IDA) O88662 (/IDA) |
Regulation of angiogenesis GO:0045765
Any process that modulates the frequency, rate or extent of angiogenesis.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Actin-mediated cell contraction GO:0070252
The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
|
2 | O88662 (/IDA) O88662 (/IDA) |
Positive regulation of integrin-mediated signaling pathway GO:2001046
Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway.
|
2 | O88662 (/IMP) O88662 (/IMP) |
Positive regulation of integrin-mediated signaling pathway GO:2001046
Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Regulation of vasculogenesis GO:2001212
Any process that modulates the frequency, rate or extent of vasculogenesis.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Positive regulation of cell-matrix adhesion GO:0001954
Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.
|
1 | P54851 (/IDA) |
Regulation of glomerular filtration GO:0003093
Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule.
|
1 | P54851 (/IDA) |
Regulation of glomerular filtration GO:0003093
Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule.
|
1 | F1QIK8 (/IMP) |
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
|
1 | P54851 (/IDA) |
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
1 | P54851 (/IDA) |
Cell-matrix adhesion GO:0007160
The binding of a cell to the extracellular matrix via adhesion molecules.
|
1 | P54851 (/IDA) |
Cell death GO:0008219
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
|
1 | P54851 (/IDA) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | P54851 (/IMP) |
Regulation of endothelial cell migration GO:0010594
Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
1 | P54851 (/IDA) |
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
1 | P54851 (/IDA) |
Bleb assembly GO:0032060
The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.
|
1 | P54851 (/IDA) |
Activation of protein kinase activity GO:0032147
Any process that initiates the activity of an inactive protein kinase.
|
1 | P54851 (/IDA) |
Protein localization to cell surface GO:0034394
A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.
|
1 | P54851 (/IMP) |
Blood vessel endothelial cell migration GO:0043534
The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis.
|
1 | P54851 (/IDA) |
Regulation of kinase activity GO:0043549
Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
|
1 | P54851 (/IDA) |
Regulation of angiogenesis GO:0045765
Any process that modulates the frequency, rate or extent of angiogenesis.
|
1 | P54851 (/IDA) |
Regulation of angiogenesis GO:0045765
Any process that modulates the frequency, rate or extent of angiogenesis.
|
1 | P54851 (/IMP) |
Actin-mediated cell contraction GO:0070252
The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.
|
1 | P54851 (/IDA) |
Positive regulation of integrin-mediated signaling pathway GO:2001046
Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway.
|
1 | P54851 (/IDA) |
Regulation of vasculogenesis GO:2001212
Any process that modulates the frequency, rate or extent of vasculogenesis.
|
1 | P54851 (/IDA) |
There are 20 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
8 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) F1QIK8 (/ISS) O88662 (/ISS) O88662 (/ISS) P54851 (/ISS) Q2NKU9 (/ISS) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
6 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) P54851 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
6 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) P54851 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
|
6 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) P54851 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) F1QIK8 (/ISS) Q2NKU9 (/ISS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
5 | A5A6N6 (/ISS) A5A6N6 (/ISS) A5A6N6 (/ISS) Q2NKU9 (/ISS) Q66HH2 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | O88662 (/IDA) O88662 (/IDA) P54851 (/IDA) Q66HH2 (/IDA) |
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
3 | O88662 (/IDA) O88662 (/IDA) P54851 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
2 | O88662 (/IDA) O88662 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | O88662 (/IDA) O88662 (/IDA) |
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
2 | O88662 (/IDA) O88662 (/IDA) |
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
2 | O88662 (/ISO) O88662 (/ISO) |
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
|
2 | O88662 (/IDA) O88662 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q66HH2 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P54851 (/IDA) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P54851 (/TAS) |