The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17: Claudin-12 (Predicted)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
16 P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS)
(6 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
15 P56749 (/IPI) P56749 (/IPI) P56749 (/IPI) P56749 (/IPI) P56749 (/IPI) P56749 (/IPI) P56749 (/IPI) P56749 (/IPI) P56749 (/IPI) P56749 (/IPI)
(5 more)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules GO:0016338
The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.
16 P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS)
(6 more)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
16 P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS) P56749 (/ISS)
(6 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
15 P56749 (/IDA) P56749 (/IDA) P56749 (/IDA) P56749 (/IDA) P56749 (/IDA) P56749 (/IDA) P56749 (/IDA) P56749 (/IDA) P56749 (/IDA) P56749 (/IDA)
(5 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9ET43 (/ISO)
Lateral plasma membrane GO:0016328
The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells.
1 Q9ET43 (/IDA)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
1 Q9ET43 (/IDA)
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