The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
AhpD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1: Sestrin 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Leucine binding GO:0070728
Interacting selectively and non-covalently with 2-amino-4-methylpentanoic acid.
12 P58003 (/ISS) P58003 (/ISS) P58006 (/ISS) P58043 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q58CN8 (/ISS)
(2 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 P58004 (/IPI) P58004 (/IPI) P58005 (/IPI) P58006 (/IPI) P58043 (/IPI) Q9CYP7 (/IPI) Q9CYP7 (/IPI) Q9Y6P5 (/IPI) Q9Y6P5 (/IPI)
Oxidoreductase activity, acting on peroxide as acceptor GO:0016684
Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor.
4 P58043 (/ISS) Q58CN8 (/ISS) Q58CN8 (/ISS) Q5RCB4 (/ISS)
Leucine binding GO:0070728
Interacting selectively and non-covalently with 2-amino-4-methylpentanoic acid.
4 P58004 (/IDA) P58004 (/IDA) Q9Y6P5 (/IDA) Q9Y6P5 (/IDA)
Oxidoreductase activity, acting on peroxide as acceptor GO:0016684
Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor.
2 P58004 (/IDA) P58004 (/IDA)
Sulfiredoxin activity GO:0032542
Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R.
2 P58004 (/IDA) P58004 (/IDA)
Leucine binding GO:0070728
Interacting selectively and non-covalently with 2-amino-4-methylpentanoic acid.
2 P58006 (/ISO) P58043 (/ISO)
GDP-dissociation inhibitor activity GO:0005092
Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding.
1 P58043 (/IDA)
Oxidoreductase activity, acting on peroxide as acceptor GO:0016684
Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor.
1 P58043 (/ISO)

There are 65 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of TORC1 signaling GO:1904262
Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling.
13 P58003 (/ISS) P58003 (/ISS) P58006 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q58CN8 (/ISS) Q58CN8 (/ISS)
(3 more)
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
10 P58006 (/ISS) P58043 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q58CN8 (/ISS) Q58CN8 (/ISS) Q5RCB4 (/ISS)
Negative regulation of TORC1 signaling GO:1904262
Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling.
9 P58004 (/IMP) P58004 (/IMP) P58005 (/IMP) P58006 (/IMP) P58043 (/IMP) Q9CYP7 (/IMP) Q9CYP7 (/IMP) Q9Y6P5 (/IMP) Q9Y6P5 (/IMP)
Cellular response to amino acid starvation GO:0034198
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
8 P58006 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q9CYP7 (/ISS) Q9CYP7 (/ISS)
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
6 P58004 (/IMP) P58004 (/IMP) P58006 (/IMP) P58043 (/IMP) Q9CYP7 (/IMP) Q9CYP7 (/IMP)
Cellular oxidant detoxification GO:0098869
Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.
6 P58006 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
5 P58004 (/ISS) P58004 (/ISS) Q58CN8 (/ISS) Q58CN8 (/ISS) Q5RCB4 (/ISS)
Cellular response to amino acid starvation GO:0034198
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
5 P58004 (/IMP) P58004 (/IMP) P58005 (/IMP) Q9Y6P5 (/IMP) Q9Y6P5 (/IMP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
5 P58004 (/ISS) P58004 (/ISS) Q58CN8 (/ISS) Q58CN8 (/ISS) Q5RCB4 (/ISS)
Cellular response to glucose starvation GO:0042149
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.
5 P58004 (/IMP) P58004 (/IMP) P58005 (/IMP) Q9Y6P5 (/IMP) Q9Y6P5 (/IMP)
Positive regulation of macroautophagy GO:0016239
Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.
4 P58043 (/ISS) Q58CN8 (/ISS) Q58CN8 (/ISS) Q5RCB4 (/ISS)
Cellular response to amino acid starvation GO:0034198
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
4 P58006 (/ISO) P58043 (/ISO) Q9CYP7 (/ISO) Q9CYP7 (/ISO)
Positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress GO:0036091
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
4 P58043 (/ISS) Q58CN8 (/ISS) Q58CN8 (/ISS) Q5RCB4 (/ISS)
Cellular response to glucose starvation GO:0042149
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.
4 P58006 (/ISO) P58043 (/ISO) Q9CYP7 (/ISO) Q9CYP7 (/ISO)
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
4 P58004 (/IMP) P58004 (/IMP) Q9Y6P5 (/IMP) Q9Y6P5 (/IMP)
Cellular oxidant detoxification GO:0098869
Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.
4 P58004 (/IMP) P58004 (/IMP) Q9Y6P5 (/IMP) Q9Y6P5 (/IMP)
Positive regulation of protein localization to nucleus GO:1900182
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
4 P58043 (/ISS) Q58CN8 (/ISS) Q58CN8 (/ISS) Q5RCB4 (/ISS)
Negative regulation of TORC1 signaling GO:1904262
Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling.
4 P58006 (/ISO) P58043 (/ISO) Q9CYP7 (/ISO) Q9CYP7 (/ISO)
Cellular response to leucine starvation GO:1990253
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.
4 P58043 (/ISS) Q58CN8 (/ISS) Q58CN8 (/ISS) Q5RCB4 (/ISS)
Regulation of protein phosphorylation GO:0001932
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
3 Q58CN8 (/ISS) Q58CN8 (/ISS) Q5RCB4 (/ISS)
Determination of left/right symmetry GO:0007368
The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
3 Q5RGN4 (/IMP) Q6DG05 (/IMP) U3JAG5 (/IMP)
DNA damage response, signal transduction by p53 class mediator GO:0030330
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
3 P58004 (/IMP) P58004 (/IMP) P58043 (/IMP)
DNA damage response, signal transduction by p53 class mediator GO:0030330
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
3 Q58CN8 (/ISS) Q58CN8 (/ISS) Q5RCB4 (/ISS)
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
3 P58043 (/IGI) Q9CYP7 (/IGI) Q9CYP7 (/IGI)
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
3 P58043 (/IMP) Q9CYP7 (/IMP) Q9CYP7 (/IMP)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
3 P58043 (/IGI) Q9CYP7 (/IGI) Q9CYP7 (/IGI)
Regulation of protein kinase B signaling GO:0051896
Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
3 P58006 (/IDA) Q9CYP7 (/IDA) Q9CYP7 (/IDA)
Negative regulation of translation in response to endoplasmic reticulum stress GO:1902010
Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.
3 P58004 (/IMP) P58004 (/IMP) P58043 (/IMP)
Negative regulation of translation in response to endoplasmic reticulum stress GO:1902010
Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.
3 Q58CN8 (/ISS) Q58CN8 (/ISS) Q5RCB4 (/ISS)
Regulation of protein phosphorylation GO:0001932
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
2 P58004 (/IDA) P58004 (/IDA)
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
2 F1R1P4 (/IMP) Q7ZVJ7 (/IMP)
Positive regulation of macroautophagy GO:0016239
Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.
2 P58004 (/IMP) P58004 (/IMP)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
2 P58006 (/IDA) P58043 (/IDA)
Positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress GO:0036091
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 P58004 (/IMP) P58004 (/IMP)
TORC2 signaling GO:0038203
A series of intracellular molecular signals mediated by TORC2; TOR (rapamycin-insensitive companion of TOR) in complex with at least Rictor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.
2 Q9CYP7 (/IMP) Q9CYP7 (/IMP)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
2 Q9CYP7 (/IMP) Q9CYP7 (/IMP)
Regulation of insulin receptor signaling pathway GO:0046626
Any process that modulates the frequency, rate or extent of insulin receptor signaling.
2 Q9CYP7 (/IMP) Q9CYP7 (/IMP)
Cellular response to leucine GO:0071233
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus.
2 P58004 (/IMP) P58004 (/IMP)
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
2 P58006 (/ISO) P58043 (/ISO)
Cellular oxidant detoxification GO:0098869
Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.
2 P58004 (/IDA) P58004 (/IDA)
Positive regulation of protein localization to nucleus GO:1900182
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
2 P58004 (/IMP) P58004 (/IMP)
Cellular response to leucine starvation GO:1990253
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.
2 P58004 (/IMP) P58004 (/IMP)
Regulation of protein phosphorylation GO:0001932
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
1 P58043 (/IMP)
Regulation of protein phosphorylation GO:0001932
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
1 P58043 (/ISO)
Regulation of gluconeogenesis GO:0006111
Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
1 P58043 (/IMP)
Fatty acid beta-oxidation GO:0006635
A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
1 P58043 (/IGI)
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
1 P58043 (/IMP)
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
1 P58043 (/IGI)
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
1 P58043 (/IMP)
Positive regulation of macroautophagy GO:0016239
Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.
1 P58043 (/ISO)
DNA damage response, signal transduction by p53 class mediator GO:0030330
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
1 P58043 (/ISO)
Mitochondrial DNA metabolic process GO:0032042
The chemical reactions and pathways involving mitochondrial DNA.
1 P58043 (/IMP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 P58043 (/IMP)
Positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress GO:0036091
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 P58043 (/ISO)
Protein kinase B signaling GO:0043491
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.
1 P58043 (/IMP)
Glucose import GO:0046323
The directed movement of the hexose monosaccharide glucose into a cell or organelle.
1 P58043 (/IMP)
Triglyceride homeostasis GO:0070328
Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.
1 P58043 (/IMP)
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
1 P58043 (/ISO)
Cellular response to leucine GO:0071233
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus.
1 P58043 (/ISO)
Cellular oxidant detoxification GO:0098869
Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.
1 P58006 (/ISO)
Positive regulation of protein localization to nucleus GO:1900182
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
1 P58043 (/ISO)
Negative regulation of translation in response to endoplasmic reticulum stress GO:1902010
Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.
1 P58043 (/ISO)
Positive regulation of lipophagy GO:1904504
Any process that activates or increases the frequency, rate or extent of lipophagy.
1 P58043 (/IMP)
Cellular response to leucine starvation GO:1990253
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.
1 P58043 (/ISO)
Regulation of cAMP-dependent protein kinase activity GO:2000479
Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity.
1 P58043 (/IMP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
13 P58003 (/ISS) P58003 (/ISS) P58006 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q58CN8 (/ISS) Q58CN8 (/ISS)
(3 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
8 P58003 (/ISS) P58003 (/ISS) P58006 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS) Q4R6P7 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 P58004 (/IDA) P58004 (/IDA) P58005 (/IDA) Q9Y6P5 (/IDA) Q9Y6P5 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 P58006 (/ISO) P58043 (/ISO) Q9CYP7 (/ISO) Q9CYP7 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P58004 (/TAS) P58004 (/TAS) Q9Y6P5 (/TAS) Q9Y6P5 (/TAS)
Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
2 Q9Y6P5 (/IDA) Q9Y6P5 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9Y6P5 (/IDA) Q9Y6P5 (/IDA)
Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
1 P58006 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P58006 (/ISO)
CATH-Gene3D is a Global Biodata Core Resource Learn more...