CATH Superfamily 1.20.1280.50
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 18: F-box/LRR-repeat protein 7 isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
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9 | Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q5BJ29 (/IPI) |
There are 22 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
|
9 | Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) |
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
9 | Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) |
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
9 | Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) |
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
9 | Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) |
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
9 | Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) |
SCF complex assembly GO:0010265
The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex.
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9 | Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) |
Negative regulation of G2/M transition of mitotic cell cycle GO:0010972
Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
|
9 | Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) |
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
9 | Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) |
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031146
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
|
9 | Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) |
Post-translational protein modification GO:0043687
The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.
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9 | Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) |
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
2 | Q5BJ29 (/IDA) Q9VF10 (/IDA) |
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
|
1 | Q5BJ29 (/IDA) |
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
1 | Q5BJ29 (/IMP) |
Proximal/distal pattern formation, imaginal disc GO:0007449
The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.
|
1 | Q9VF10 (/IMP) |
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
1 | Q5BJ29 (/IMP) |
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031146
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
|
1 | Q5BJ29 (/IMP) |
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031146
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
|
1 | Q9VF10 (/ISM) |
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
|
1 | Q9VF10 (/IMP) |
Positive regulation of hippo signaling GO:0035332
Any process that activates or increases the frequency, rate or extent of hippo signaling.
|
1 | Q9VF10 (/IMP) |
Cellular protein catabolic process GO:0044257
The chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
|
1 | Q9VF10 (/IMP) |
Negative regulation of imaginal disc growth GO:0045571
Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth.
|
1 | Q9VF10 (/IMP) |
Negative regulation of growth GO:0045926
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
|
1 | Q9VF10 (/IMP) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Ubiquitin ligase complex GO:0000151
A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
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9 | Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) Q9UJT9 (/NAS) |
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
9 | Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
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9 | Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) Q9UJT9 (/TAS) |
SCF ubiquitin ligase complex GO:0019005
A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
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9 | Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) Q9UJT9 (/ISS) |
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
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1 | Q5BJ29 (/IDA) |
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
|
1 | Q9VF10 (/IDA) |
SCF ubiquitin ligase complex GO:0019005
A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
|
1 | Q5BJ29 (/IDA) |
SCF ubiquitin ligase complex GO:0019005
A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
|
1 | Q9VF10 (/IPI) |
SCF ubiquitin ligase complex GO:0019005
A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
|
1 | Q9VF10 (/ISM) |
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
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1 | Q9VF10 (/IDA) |