The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Arfaptin homology (AH) domain/BAR domain
".
FunFam 23: Interacting with PRKCA
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 41 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
|
12 |
Q2T9M1 (/ISS)
Q4R7Q5 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q62083 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
(2 more) |
Arp2/3 complex binding GO:0071933
Interacting selectively and non-covalently with an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5).
|
12 |
Q2T9M1 (/ISS)
Q4R7Q5 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q62083 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
(2 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
10 | Q62083 (/IPI) Q80VC8 (/IPI) Q8SY07 (/IPI) Q9EP80 (/IPI) Q9NRD5 (/IPI) Q9NRD5 (/IPI) Q9NRD5 (/IPI) Q9NRD5 (/IPI) Q9NRD5 (/IPI) Q9NRD5 (/IPI) |
Protein kinase C binding GO:0005080
Interacting selectively and non-covalently with protein kinase C.
|
8 | Q62083 (/ISS) Q9EP80 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) |
G protein-coupled receptor binding GO:0001664
Interacting selectively and non-covalently with a G protein-coupled receptor.
|
7 | Q62083 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) |
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
7 | Q9EP80 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) |
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
7 | Q9EP80 (/IPI) Q9NRD5 (/IPI) Q9NRD5 (/IPI) Q9NRD5 (/IPI) Q9NRD5 (/IPI) Q9NRD5 (/IPI) Q9NRD5 (/IPI) |
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
7 | Q62083 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
7 | Q62083 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) |
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
6 | Q9NRD5 (/IPI) Q9NRD5 (/IPI) Q9NRD5 (/IPI) Q9NRD5 (/IPI) Q9NRD5 (/IPI) Q9NRD5 (/IPI) |
Showing 1 to 10 of 41 entries
There are 59 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Positive regulation of receptor internalization GO:0002092
Any process that activates or increases the frequency, rate or extent of receptor internalization.
|
12 |
Q2T9M1 (/ISS)
Q4R7Q5 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q62083 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
(2 more) |
Glial cell development GO:0021782
The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
|
12 |
Q2T9M1 (/ISS)
Q4R7Q5 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q62083 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
(2 more) |
Negative regulation of Arp2/3 complex-mediated actin nucleation GO:0034316
Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.
|
12 |
Q2T9M1 (/ISS)
Q4R7Q5 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q62083 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
(2 more) |
Cellular response to decreased oxygen levels GO:0036294
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.
|
12 |
Q2T9M1 (/ISS)
Q4R7Q5 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q62083 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
(2 more) |
Cellular response to glucose starvation GO:0042149
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.
|
12 |
Q2T9M1 (/ISS)
Q4R7Q5 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q62083 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
(2 more) |
Long-term synaptic depression GO:0060292
A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.
|
12 |
Q2T9M1 (/ISS)
Q4R7Q5 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q62083 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
(2 more) |
Dendritic spine organization GO:0097061
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.
|
12 |
Q2T9M1 (/ISS)
Q4R7Q5 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q62083 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
(2 more) |
Dendritic spine maintenance GO:0097062
The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.
|
12 |
Q2T9M1 (/ISS)
Q4R7Q5 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q62083 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
(2 more) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
9 | Q62083 (/ISS) Q80VC8 (/ISS) Q8C1W2 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) |
Receptor clustering GO:0043113
The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
|
7 | Q9EP80 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) |
Showing 1 to 10 of 59 entries
There are 46 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
13 |
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
Q62083 (/IDA)
Q9NRD5 (/IDA)
Q9NRD5 (/IDA)
Q9NRD5 (/IDA)
(3 more) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
12 |
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
Q9NRD5 (/IDA)
Q9NRD5 (/IDA)
Q9NRD5 (/IDA)
Q9NRD5 (/IDA)
(2 more) |
Aggresome GO:0016235
An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules.
|
12 |
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
A0A024R1J5 (/IDA)
Q9NRD5 (/IDA)
Q9NRD5 (/IDA)
Q9NRD5 (/IDA)
Q9NRD5 (/IDA)
(2 more) |
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
12 |
Q2T9M1 (/ISS)
Q4R7Q5 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q5REH1 (/ISS)
Q62083 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
Q9NRD5 (/ISS)
(2 more) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
9 | Q80VC8 (/ISS) Q8C1W2 (/ISS) Q9EP80 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
7 | Q62083 (/IDA) Q9NRD5 (/IDA) Q9NRD5 (/IDA) Q9NRD5 (/IDA) Q9NRD5 (/IDA) Q9NRD5 (/IDA) Q9NRD5 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
7 | Q9EP80 (/TAS) Q9NRD5 (/TAS) Q9NRD5 (/TAS) Q9NRD5 (/TAS) Q9NRD5 (/TAS) Q9NRD5 (/TAS) Q9NRD5 (/TAS) |
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
|
7 | Q9EP80 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
7 | Q9EP80 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) Q9NRD5 (/ISS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
6 | Q9NRD5 (/IDA) Q9NRD5 (/IDA) Q9NRD5 (/IDA) Q9NRD5 (/IDA) Q9NRD5 (/IDA) Q9NRD5 (/IDA) |
Showing 1 to 10 of 46 entries