The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Shigella T3SS effector IpaH domain
".
FunFam 3: Type III secretion system effector E3 ubiquitin tr...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
12 |
D0ZRB2 (/IPI)
D0ZRB2 (/IPI)
D0ZRB2 (/IPI)
Q8ZQQ2 (/IPI)
Q8ZQQ2 (/IPI)
Q8ZQQ2 (/IPI)
Q8ZQQ2 (/IPI)
Q8ZQQ2 (/IPI)
Q8ZQQ2 (/IPI)
Q8ZQQ2 (/IPI)
(2 more) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
9 | Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) |
|
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
|
9 | Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
3 | D0ZRB2 (/ISS) D0ZRB2 (/ISS) D0ZRB2 (/ISS) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
3 | D0ZRB2 (/IDA) D0ZRB2 (/IDA) D0ZRB2 (/IDA) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
12 |
D0ZRB2 (/IDA)
D0ZRB2 (/IDA)
D0ZRB2 (/IDA)
Q8ZQQ2 (/IDA)
Q8ZQQ2 (/IDA)
Q8ZQQ2 (/IDA)
Q8ZQQ2 (/IDA)
Q8ZQQ2 (/IDA)
Q8ZQQ2 (/IDA)
Q8ZQQ2 (/IDA)
(2 more) |
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
|
9 | Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) |
|
Protein secretion by the type III secretion system GO:0030254
The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.
|
9 | Q8ZQQ2 (/ISS) Q8ZQQ2 (/ISS) Q8ZQQ2 (/ISS) Q8ZQQ2 (/ISS) Q8ZQQ2 (/ISS) Q8ZQQ2 (/ISS) Q8ZQQ2 (/ISS) Q8ZQQ2 (/ISS) Q8ZQQ2 (/ISS) |
|
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
|
9 | Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) |
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
|
3 | D0ZRB2 (/ISS) D0ZRB2 (/ISS) D0ZRB2 (/ISS) |
|
Positive regulation of cell death GO:0010942
Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
|
3 | D0ZRB2 (/IMP) D0ZRB2 (/IMP) D0ZRB2 (/IMP) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
3 | D0ZRB2 (/ISS) D0ZRB2 (/ISS) D0ZRB2 (/ISS) |
|
Protein secretion by the type III secretion system GO:0030254
The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.
|
3 | D0ZRB2 (/IDA) D0ZRB2 (/IDA) D0ZRB2 (/IDA) |
|
Negative regulation of thioredoxin peroxidase activity GO:1903124
Any process that stops, prevents or reduces the frequency, rate or extent of thioredoxin peroxidase activity.
|
3 | D0ZRB2 (/IMP) D0ZRB2 (/IMP) D0ZRB2 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Host cell cytoplasm GO:0030430
The cytoplasm of a host cell.
|
9 | Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) |
|
Host cell endoplasmic reticulum GO:0044165
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
9 | Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) |
