The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 24: Heat shock protein 70

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
2 O97125 (/ISS) P11146 (/ISS)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
15 P02825 (/IEP) P02825 (/IEP) P82910 (/IEP) P82910 (/IEP) Q8INI8 (/IEP) Q8INI8 (/IEP) Q8INI8 (/IEP) Q9BIR7 (/IEP) Q9BIR7 (/IEP) Q9BIR7 (/IEP)
(5 more)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
15 P02825 (/IMP) P02825 (/IMP) P82910 (/IMP) P82910 (/IMP) Q8INI8 (/IMP) Q8INI8 (/IMP) Q8INI8 (/IMP) Q9BIR7 (/IMP) Q9BIR7 (/IMP) Q9BIR7 (/IMP)
(5 more)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
15 P02825 (/IMP) P02825 (/IMP) P82910 (/IMP) P82910 (/IMP) Q8INI8 (/IMP) Q8INI8 (/IMP) Q8INI8 (/IMP) Q9BIR7 (/IMP) Q9BIR7 (/IMP) Q9BIR7 (/IMP)
(5 more)
Heat shock-mediated polytene chromosome puffing GO:0035080
The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus.
15 P02825 (/IMP) P02825 (/IMP) P82910 (/IMP) P82910 (/IMP) Q8INI8 (/IMP) Q8INI8 (/IMP) Q8INI8 (/IMP) Q9BIR7 (/IMP) Q9BIR7 (/IMP) Q9BIR7 (/IMP)
(5 more)
Response to unfolded protein GO:0006986
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
11 P02825 (/NAS) P02825 (/NAS) Q8INI8 (/NAS) Q8INI8 (/NAS) Q8INI8 (/NAS) Q9BIR7 (/NAS) Q9BIR7 (/NAS) Q9BIR7 (/NAS) Q9BIS2 (/NAS) Q9BIS2 (/NAS)
(1 more)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
11 P02825 (/NAS) P02825 (/NAS) Q8INI8 (/NAS) Q8INI8 (/NAS) Q8INI8 (/NAS) Q9BIR7 (/NAS) Q9BIR7 (/NAS) Q9BIR7 (/NAS) Q9BIS2 (/NAS) Q9BIS2 (/NAS)
(1 more)
Response to toxic substance GO:0009636
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
3 Q9BIR7 (/IEP) Q9BIR7 (/IEP) Q9BIR7 (/IEP)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
2 O97125 (/ISS) P11146 (/ISS)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
1 O97125 (/IMP)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 Q9GSU7 (/ISS)
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
1 O97125 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 O97125 (/ISS) P11146 (/ISS)
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