CATH Superfamily 1.20.1270.10
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 10: Heat shock 70 kDa protein 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 44 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
37 |
P08106 (/IPI)
P08106 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
(27 more) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
23 |
B3VHV2 (/IDA)
B6EAX2 (/IDA)
P08106 (/IDA)
P08106 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
(13 more) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
23 |
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV9 (/IPI)
(13 more) |
|
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
|
23 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(13 more) |
|
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
|
23 |
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV9 (/TAS)
(13 more) |
|
G protein-coupled receptor binding GO:0001664
Interacting selectively and non-covalently with a G protein-coupled receptor.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
18 |
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV9 (/HDA)
(8 more) |
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
18 |
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV9 (/IPI)
(8 more) |
|
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
|
18 |
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV9 (/IPI)
(8 more) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
18 |
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV9 (/IPI)
(8 more) |
|
ATPase activity, coupled GO:0042623
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
ATPase activity, coupled GO:0042623
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
|
18 |
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV9 (/TAS)
(8 more) |
|
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
18 |
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV9 (/IPI)
(8 more) |
|
Protein folding chaperone GO:0044183
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) that contributes to the process of protein folding.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
18 |
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV9 (/IPI)
(8 more) |
|
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
|
18 |
P0DMV8 (/NAS)
P0DMV8 (/NAS)
P0DMV8 (/NAS)
P0DMV8 (/NAS)
P0DMV8 (/NAS)
P0DMV8 (/NAS)
P0DMV8 (/NAS)
P0DMV8 (/NAS)
P0DMV8 (/NAS)
P0DMV9 (/NAS)
(8 more) |
|
C3HC4-type RING finger domain binding GO:0055131
Interacting selectively and non-covalently with a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid. Many proteins containing a C3HC4-type RING finger play a key role in the ubiquitination pathway.
|
18 |
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV9 (/IPI)
(8 more) |
|
Disordered domain specific binding GO:0097718
Interacting selectively and non-covalently with a disordered domain of a protein.
|
16 |
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P0DMV8 (/IPI)
P54652 (/IPI)
(6 more) |
|
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
|
9 | P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) |
|
Denatured protein binding GO:0031249
Interacting selectively and non-covalently with denatured proteins.
|
9 | P0DMV8 (/IPI) P0DMV8 (/IPI) P0DMV8 (/IPI) P0DMV8 (/IPI) P0DMV8 (/IPI) P0DMV8 (/IPI) P0DMV8 (/IPI) P0DMV8 (/IPI) P0DMV8 (/IPI) |
|
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
|
9 | P0DMV8 (/HDA) P0DMV8 (/HDA) P0DMV8 (/HDA) P0DMV8 (/HDA) P0DMV8 (/HDA) P0DMV8 (/HDA) P0DMV8 (/HDA) P0DMV8 (/HDA) P0DMV8 (/HDA) |
|
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
|
5 | P0DMW0 (/ISS) P0DMW0 (/ISS) P34930 (/ISS) Q27975 (/ISS) Q27975 (/ISS) |
|
Progesterone receptor binding GO:0033142
Interacting selectively and non-covalently with a progesterone receptor.
|
5 | B3VHV2 (/IPI) B6EAX2 (/IPI) P08106 (/IPI) P08106 (/IPI) Q7SX63 (/IPI) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
3 | P17156 (/ISO) P17156 (/ISO) P17156 (/ISO) |
|
Tau protein binding GO:0048156
Interacting selectively and non-covalently with tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS.
|
3 | P14659 (/IPI) P14659 (/IPI) P14659 (/IPI) |
|
Tau protein binding GO:0048156
Interacting selectively and non-covalently with tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS.
|
3 | P17156 (/ISO) P17156 (/ISO) P17156 (/ISO) |
|
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
|
3 | P17156 (/ISO) P17156 (/ISO) P17156 (/ISO) |
|
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
|
3 | P14659 (/IPI) P14659 (/IPI) P14659 (/IPI) |
|
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
|
3 | P17156 (/ISO) P17156 (/ISO) P17156 (/ISO) |
|
Glycolipid binding GO:0051861
Interacting selectively and non-covalently with a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate.
|
3 | P17156 (/IDA) P17156 (/IDA) P17156 (/IDA) |
|
Disordered domain specific binding GO:0097718
Interacting selectively and non-covalently with a disordered domain of a protein.
|
3 | P17156 (/ISO) P17156 (/ISO) P17156 (/ISO) |
|
Protease binding GO:0002020
Interacting selectively and non-covalently with any protease or peptidase.
|
2 | P0DMW1 (/IPI) P0DMW1 (/IPI) |
|
NF-kappaB binding GO:0051059
Interacting selectively and non-covalently with NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.
|
2 | P0DMW1 (/IPI) P0DMW1 (/IPI) |
|
G protein-coupled receptor binding GO:0001664
Interacting selectively and non-covalently with a G protein-coupled receptor.
|
1 | Q7SX63 (/ISS) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q7SX63 (/ISS) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q7SX63 (/ISS) |
|
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
1 | Q7SX63 (/ISS) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q7SX63 (/ISS) |
|
MHC class II protein complex binding GO:0023026
Interacting selectively and non-covalently with the class II major histocompatibility complex.
|
1 | Q7SX63 (/ISS) |
|
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
|
1 | Q7SX63 (/ISS) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | Q7SX63 (/ISS) |
|
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
|
1 | Q7SX63 (/ISS) |
|
C3HC4-type RING finger domain binding GO:0055131
Interacting selectively and non-covalently with a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid. Many proteins containing a C3HC4-type RING finger play a key role in the ubiquitination pathway.
|
1 | Q7SX63 (/ISS) |
There are 88 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
126 |
A0A024R6B5 (/ISS)
A0A024R6B5 (/ISS)
A0A024R6B5 (/ISS)
A0A024R6B5 (/ISS)
A0A024R6B5 (/ISS)
A0A061I5U1 (/ISS)
A0A087QQM7 (/ISS)
A0A087QQM7 (/ISS)
A0A087QQM7 (/ISS)
A0A087V8L3 (/ISS)
(116 more) |
|
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
|
126 |
A0A024R6B5 (/ISS)
A0A024R6B5 (/ISS)
A0A024R6B5 (/ISS)
A0A024R6B5 (/ISS)
A0A024R6B5 (/ISS)
A0A061I5U1 (/ISS)
A0A087QQM7 (/ISS)
A0A087QQM7 (/ISS)
A0A087QQM7 (/ISS)
A0A087V8L3 (/ISS)
(116 more) |
|
Protein refolding GO:0042026
The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
|
25 |
P0DMW0 (/ISS)
P0DMW0 (/ISS)
P0DMW1 (/ISS)
P0DMW1 (/ISS)
P34930 (/ISS)
Q27965 (/ISS)
Q27965 (/ISS)
Q27975 (/ISS)
Q27975 (/ISS)
Q28222 (/ISS)
(15 more) |
|
Positive regulation of microtubule nucleation GO:0090063
Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
|
24 |
P0DMW0 (/ISS)
P0DMW0 (/ISS)
P0DMW1 (/ISS)
P0DMW1 (/ISS)
P34930 (/ISS)
Q27965 (/ISS)
Q27965 (/ISS)
Q27975 (/ISS)
Q27975 (/ISS)
Q28222 (/ISS)
(14 more) |
|
Regulation of mitotic spindle assembly GO:1901673
Any process that modulates the frequency, rate or extent of mitotic spindle assembly.
|
24 |
P0DMW0 (/ISS)
P0DMW0 (/ISS)
P0DMW1 (/ISS)
P0DMW1 (/ISS)
P34930 (/ISS)
Q27965 (/ISS)
Q27965 (/ISS)
Q27975 (/ISS)
Q27975 (/ISS)
Q28222 (/ISS)
(14 more) |
|
Protein refolding GO:0042026
The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
|
23 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(13 more) |
|
Negative regulation of inclusion body assembly GO:0090084
Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
|
23 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(13 more) |
|
MRNA catabolic process GO:0006402
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Regulation of protein ubiquitination GO:0031396
Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
Negative regulation of protein ubiquitination GO:0031397
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
Positive regulation of interleukin-8 production GO:0032757
Any process that activates or increases the frequency, rate, or extent of interleukin-8 production.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
18 |
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV9 (/TAS)
(8 more) |
|
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
Protein refolding GO:0042026
The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
18 |
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV9 (/TAS)
(8 more) |
|
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
|
18 |
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV9 (/TAS)
(8 more) |
|
Positive regulation of erythrocyte differentiation GO:0045648
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
|
18 |
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV9 (/TAS)
(8 more) |
|
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Negative regulation of cell death GO:0060548
Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Cellular heat acclimation GO:0070370
Any process that increases heat tolerance of a cell in response to high temperatures.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway GO:0070434
Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Positive regulation of microtubule nucleation GO:0090063
Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Regulation of cellular response to heat GO:1900034
Any process that modulates the frequency, rate or extent of cellular response to heat.
|
18 |
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV9 (/TAS)
(8 more) |
|
Regulation of mitotic spindle assembly GO:1901673
Any process that modulates the frequency, rate or extent of mitotic spindle assembly.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Positive regulation of tumor necrosis factor-mediated signaling pathway GO:1903265
Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240
Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.
|
18 |
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV8 (/IMP)
P0DMV9 (/IMP)
(8 more) |
|
Lysosomal transport GO:0007041
The directed movement of substances into, out of or within a lysosome.
|
14 |
P0DMV8 (/ISS)
P0DMV8 (/ISS)
P0DMV8 (/ISS)
P0DMV8 (/ISS)
P0DMV8 (/ISS)
P0DMV8 (/ISS)
P0DMV8 (/ISS)
P0DMV8 (/ISS)
P0DMV8 (/ISS)
P0DMW0 (/ISS)
(4 more) |
|
Negative regulation of cell death GO:0060548
Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
|
11 |
P0DMV9 (/IDA)
P0DMV9 (/IDA)
P0DMV9 (/IDA)
P0DMV9 (/IDA)
P0DMV9 (/IDA)
P0DMV9 (/IDA)
P0DMV9 (/IDA)
P0DMV9 (/IDA)
P0DMV9 (/IDA)
P0DMW0 (/IDA)
(1 more) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
10 | P14659 (/ISS) P14659 (/ISS) P14659 (/ISS) P34933 (/ISS) P54652 (/ISS) P54652 (/ISS) P54652 (/ISS) P54652 (/ISS) P54652 (/ISS) Q9TUG3 (/ISS) |
|
Response to unfolded protein GO:0006986
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
|
9 | P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) |
|
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
|
9 | P0DMV8 (/IMP) P0DMV8 (/IMP) P0DMV8 (/IMP) P0DMV8 (/IMP) P0DMV8 (/IMP) P0DMV8 (/IMP) P0DMV8 (/IMP) P0DMV8 (/IMP) P0DMV8 (/IMP) |
|
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
9 | P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) |
|
Positive regulation of RNA splicing GO:0033120
Any process that activates or increases the frequency, rate or extent of RNA splicing.
|
9 | P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) |
|
Cellular response to unfolded protein GO:0034620
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
|
9 | P0DMV8 (/IMP) P0DMV8 (/IMP) P0DMV8 (/IMP) P0DMV8 (/IMP) P0DMV8 (/IMP) P0DMV8 (/IMP) P0DMV8 (/IMP) P0DMV8 (/IMP) P0DMV8 (/IMP) |
|
Regulation of mRNA stability GO:0043488
Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
|
9 | P0DMV8 (/TAS) P0DMV8 (/TAS) P0DMV8 (/TAS) P0DMV8 (/TAS) P0DMV8 (/TAS) P0DMV8 (/TAS) P0DMV8 (/TAS) P0DMV8 (/TAS) P0DMV8 (/TAS) |
|
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
|
9 | P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) |
|
Chaperone-mediated protein complex assembly GO:0051131
The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.
|
9 | P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) |
|
Negative regulation of transcription from RNA polymerase II promoter in response to stress GO:0097201
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
|
9 | P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) |
|
Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901029
Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
|
9 | P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) |
|
Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway GO:1902236
Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.
|
9 | P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) |
|
Positive regulation of endoribonuclease activity GO:1902380
Any process that activates or increases the frequency, rate or extent of endoribonuclease activity.
|
9 | P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) P0DMV8 (/IDA) |
|
Response to unfolded protein GO:0006986
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
|
5 | P54652 (/TAS) P54652 (/TAS) P54652 (/TAS) P54652 (/TAS) P54652 (/TAS) |
|
Male meiotic nuclear division GO:0007140
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
|
5 | P54652 (/TAS) P54652 (/TAS) P54652 (/TAS) P54652 (/TAS) P54652 (/TAS) |
|
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
|
5 | P54652 (/TAS) P54652 (/TAS) P54652 (/TAS) P54652 (/TAS) P54652 (/TAS) |
|
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
5 | B3VHV2 (/IDA) B6EAX2 (/IDA) P08106 (/IDA) P08106 (/IDA) Q7SX63 (/IDA) |
|
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
|
5 | B3VHV2 (/IDA) B6EAX2 (/IDA) P08106 (/IDA) P08106 (/IDA) Q7SX63 (/IDA) |
|
Response to organonitrogen compound GO:0010243
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
|
5 | B3VHV2 (/IDA) B6EAX2 (/IDA) P08106 (/IDA) P08106 (/IDA) Q7SX63 (/IDA) |
|
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
5 | B3VHV2 (/IDA) B6EAX2 (/IDA) P08106 (/IDA) P08106 (/IDA) Q7SX63 (/IDA) |
|
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
|
5 | B3VHV2 (/IDA) B6EAX2 (/IDA) P08106 (/IDA) P08106 (/IDA) Q7SX63 (/IDA) |
|
Negative regulation of transcription from RNA polymerase II promoter in response to stress GO:0097201
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
|
5 | P0DMW0 (/ISS) P0DMW0 (/ISS) P34930 (/ISS) Q27975 (/ISS) Q27975 (/ISS) |
|
MRNA catabolic process GO:0006402
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
|
4 | P0DMW0 (/ISS) P0DMW0 (/ISS) P0DMW1 (/ISS) P0DMW1 (/ISS) |
|
Response to unfolded protein GO:0006986
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
|
4 | P0DMW0 (/IMP) P0DMW0 (/IMP) P0DMW1 (/IMP) P0DMW1 (/IMP) |
|
Response to unfolded protein GO:0006986
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
|
4 | P0DMW0 (/ISS) P0DMW0 (/ISS) P0DMW1 (/ISS) P0DMW1 (/ISS) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
4 | P0DMW0 (/ISS) P0DMW0 (/ISS) P0DMW1 (/ISS) P0DMW1 (/ISS) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
4 | P0DMW0 (/ISS) P0DMW0 (/ISS) P0DMW1 (/ISS) P0DMW1 (/ISS) |
|
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
|
3 | P17156 (/IMP) P17156 (/IMP) P17156 (/IMP) |
|
Male meiotic nuclear division GO:0007140
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
|
3 | P17156 (/IMP) P17156 (/IMP) P17156 (/IMP) |
|
Male meiosis I GO:0007141
A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.
|
3 | P17156 (/IMP) P17156 (/IMP) P17156 (/IMP) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
3 | P17156 (/IMP) P17156 (/IMP) P17156 (/IMP) |
|
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
|
3 | P17156 (/IMP) P17156 (/IMP) P17156 (/IMP) |
|
Positive regulation of G2/M transition of mitotic cell cycle GO:0010971
Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
|
3 | P17156 (/IMP) P17156 (/IMP) P17156 (/IMP) |
|
Positive regulation of ATPase activity GO:0032781
Any process that activates or increases the rate of ATP hydrolysis by an ATPase.
|
3 | P17156 (/IMP) P17156 (/IMP) P17156 (/IMP) |
|
Protein refolding GO:0042026
The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
|
3 | P17156 (/ISO) P17156 (/ISO) P17156 (/ISO) |
|
Synaptonemal complex disassembly GO:0070194
The controlled breakdown of a synaptonemal complex.
|
3 | P17156 (/IMP) P17156 (/IMP) P17156 (/IMP) |
|
Negative regulation of inclusion body assembly GO:0090084
Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
|
3 | P17156 (/ISO) P17156 (/ISO) P17156 (/ISO) |
|
Positive regulation of ATPase-coupled calcium transmembrane transporter activity GO:1901896
Any process that activates or increases the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.
|
3 | P17156 (/IMP) P17156 (/IMP) P17156 (/IMP) |
|
Positive regulation of T cell mediated cytotoxicity GO:0001916
Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity.
|
2 | P0DMW1 (/IDA) P0DMW1 (/IDA) |
|
Response to ischemia GO:0002931
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.
|
2 | P0DMW0 (/IEP) P0DMW0 (/IEP) |
|
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
|
2 | P0DMW1 (/IDA) P0DMW1 (/IDA) |
|
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
|
2 | P0DMW0 (/IEP) P0DMW0 (/IEP) |
|
Response to mechanical stimulus GO:0009612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
|
2 | P0DMW0 (/IEP) P0DMW0 (/IEP) |
|
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
2 | P0DMW0 (/IEP) P0DMW0 (/IEP) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
2 | P0DMW1 (/IDA) P0DMW1 (/IDA) |
|
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154
Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
|
2 | P0DMW1 (/IDA) P0DMW1 (/IDA) |
|
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
|
2 | P0DMW0 (/IEP) P0DMW0 (/IEP) |
|
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
2 | P0DMW0 (/IMP) P0DMW0 (/IMP) |
|
Negative regulation of vasoconstriction GO:0045906
Any process that stops, prevents, or reduces the frequency, rate or extent of vasoconstriction.
|
2 | P0DMW1 (/IMP) P0DMW1 (/IMP) |
|
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
1 | Q7SX63 (/ISS) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q7SX63 (/ISS) |
|
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q7SX63 (/ISS) |
|
Negative regulation of supramolecular fiber organization GO:1902904
Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization.
|
1 | Q7SX63 (/ISS) |
There are 54 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
30 |
B3VHV2 (/IDA)
B6EAX2 (/IDA)
P08106 (/IDA)
P08106 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
(20 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
25 |
B3VHV2 (/IDA)
B6EAX2 (/IDA)
P08106 (/IDA)
P08106 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
(15 more) |
|
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
24 |
P0DMW0 (/ISS)
P0DMW0 (/ISS)
P0DMW1 (/ISS)
P0DMW1 (/ISS)
P34930 (/ISS)
Q27965 (/ISS)
Q27965 (/ISS)
Q27975 (/ISS)
Q27975 (/ISS)
Q28222 (/ISS)
(14 more) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
24 |
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV9 (/HDA)
(14 more) |
|
Blood microparticle GO:0072562
A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.
|
23 |
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV9 (/HDA)
(13 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
22 |
P08106 (/IDA)
P08106 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
(12 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
21 |
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV9 (/TAS)
(11 more) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
20 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(10 more) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
18 |
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV9 (/TAS)
(8 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
18 |
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV9 (/TAS)
(8 more) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
18 |
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV9 (/TAS)
(8 more) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
18 |
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV9 (/TAS)
(8 more) |
|
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
Centriole GO:0005814
A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
18 |
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV9 (/TAS)
(8 more) |
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
18 |
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV9 (/HDA)
(8 more) |
|
Inclusion body GO:0016234
A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
Aggresome GO:0016235
An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
|
18 |
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV8 (/HDA)
P0DMV9 (/HDA)
(8 more) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
Ficolin-1-rich granule lumen GO:1904813
Any membrane-enclosed lumen that is part of a ficolin-1-rich granule.
|
18 |
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV8 (/TAS)
P0DMV9 (/TAS)
(8 more) |
|
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
18 |
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV8 (/IDA)
P0DMV9 (/IDA)
(8 more) |
|
CatSper complex GO:0036128
A sperm-specific voltage-gated calcium channel that controls the intracellular calcium ion concentration and, thereby, the swimming behavior of sperm. Consists of a heteromeric tetramer surrounding a calcium ion- selective pore. May also contain additional auxiliary subunits.
|
10 | P14659 (/ISS) P14659 (/ISS) P14659 (/ISS) P34933 (/ISS) P54652 (/ISS) P54652 (/ISS) P54652 (/ISS) P54652 (/ISS) P54652 (/ISS) Q9TUG3 (/ISS) |
|
Meiotic spindle GO:0072687
A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle.
|
10 | P14659 (/ISS) P14659 (/ISS) P14659 (/ISS) P34933 (/ISS) P54652 (/ISS) P54652 (/ISS) P54652 (/ISS) P54652 (/ISS) P54652 (/ISS) Q9TUG3 (/ISS) |
|
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
|
5 | B3VHV2 (/IDA) B6EAX2 (/IDA) P08106 (/IDA) P08106 (/IDA) Q7SX63 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | P54652 (/HDA) P54652 (/HDA) P54652 (/HDA) P54652 (/HDA) P54652 (/HDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
5 | P54652 (/HDA) P54652 (/HDA) P54652 (/HDA) P54652 (/HDA) P54652 (/HDA) |
|
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
|
5 | B3VHV2 (/IDA) B6EAX2 (/IDA) P08106 (/IDA) P08106 (/IDA) Q7SX63 (/IDA) |
|
Receptor complex GO:0043235
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
5 | B3VHV2 (/IDA) B6EAX2 (/IDA) P08106 (/IDA) P08106 (/IDA) Q7SX63 (/IDA) |
|
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
4 | P0DMW0 (/ISS) P0DMW0 (/ISS) P0DMW1 (/ISS) P0DMW1 (/ISS) |
|
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
4 | P0DMW0 (/IDA) P0DMW0 (/IDA) P0DMW1 (/IDA) P0DMW1 (/IDA) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
4 | P0DMW0 (/ISS) P0DMW0 (/ISS) P0DMW1 (/ISS) P0DMW1 (/ISS) |
|
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
4 | Q28222 (/ISS) Q7SX63 (/ISS) Q7YQC6 (/ISS) Q7YQC6 (/ISS) |
|
Synaptonemal complex GO:0000795
A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other. Transverse filaments connect the lateral elements to the central element.
|
3 | P17156 (/IDA) P17156 (/IDA) P17156 (/IDA) |
|
Male germ cell nucleus GO:0001673
The nucleus of a male germ cell, a reproductive cell in males.
|
3 | P17156 (/IDA) P17156 (/IDA) P17156 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | P0DMW0 (/ISS) P0DMW0 (/ISS) Q7SX63 (/ISS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
3 | P17156 (/HDA) P17156 (/HDA) P17156 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | P17156 (/ISO) P17156 (/ISO) P17156 (/ISO) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
3 | P17156 (/IDA) P17156 (/IDA) P17156 (/IDA) |
|
CatSper complex GO:0036128
A sperm-specific voltage-gated calcium channel that controls the intracellular calcium ion concentration and, thereby, the swimming behavior of sperm. Consists of a heteromeric tetramer surrounding a calcium ion- selective pore. May also contain additional auxiliary subunits.
|
3 | P17156 (/IDA) P17156 (/IDA) P17156 (/IDA) |
|
Myelin sheath GO:0043209
An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
|
3 | P17156 (/HDA) P17156 (/HDA) P17156 (/HDA) |
|
Meiotic spindle GO:0072687
A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle.
|
3 | P17156 (/IDA) P17156 (/IDA) P17156 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | P0DMW0 (/ISS) P0DMW0 (/ISS) |
|
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
2 | P0DMW1 (/IDA) P0DMW1 (/IDA) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
2 | P0DMW1 (/IDA) P0DMW1 (/IDA) |
|
Ubiquitin ligase complex GO:0000151
A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
|
1 | Q7SX63 (/ISS) |
|
Prp19 complex GO:0000974
A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p.
|
1 | Q7SX63 (/ISS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q7SX63 (/ISS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q7SX63 (/ISS) |
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
1 | Q7SX63 (/ISS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q7SX63 (/ISS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q7SX63 (/ISS) |
|
Blood microparticle GO:0072562
A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.
|
1 | Q7SX63 (/ISS) |
