The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Thymic stromal lymphopoietin
".
FunFam 2: Thymic stromal lymphopoietin
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
1 | Q9JIE6 (/IDA) |
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
1 | Q9JIE6 (/ISO) |
|
Interleukin-7 receptor binding GO:0005139
Interacting selectively and non-covalently with the interleukin-7 receptor.
|
1 | Q9JIE6 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9JIE6 (/IPI) |
There are 19 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of cytokine-mediated signaling pathway GO:0001961
Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.
|
1 | Q9JIE6 (/ISO) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | Q9JIE6 (/ISO) |
|
Positive regulation of chemokine production GO:0032722
Any process that activates or increases the frequency, rate, or extent of chemokine production.
|
1 | Q9JIE6 (/ISO) |
|
Positive regulation of interleukin-10 production GO:0032733
Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.
|
1 | Q9JIE6 (/ISO) |
|
Positive regulation of interleukin-13 production GO:0032736
Any process that activates or increases the frequency, rate, or extent of interleukin-13 production.
|
1 | Q9JIE6 (/ISO) |
|
Positive regulation of interleukin-5 production GO:0032754
Any process that activates or increases the frequency, rate, or extent of interleukin-5 production.
|
1 | Q9JIE6 (/ISO) |
|
Positive regulation of interleukin-6 production GO:0032755
Any process that activates or increases the frequency, rate, or extent of interleukin-6 production.
|
1 | Q9JIE6 (/ISO) |
|
Positive regulation of mast cell activation GO:0033005
Any process that activates or increases the frequency, rate, or extent of mast cell activation.
|
1 | Q9JIE6 (/ISO) |
|
Positive regulation of tyrosine phosphorylation of STAT protein GO:0042531
Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
|
1 | Q9JIE6 (/ISO) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q9JIE6 (/ISO) |
|
Negative regulation of growth of symbiont on or near host surface GO:0044140
Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in the symbiont's size or mass on or near the cells or tissues of the host organism.
|
1 | Q9JIE6 (/ISO) |
|
Positive regulation of inflammatory response GO:0050729
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
|
1 | Q9JIE6 (/ISO) |
|
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
|
1 | Q9JIE6 (/ISO) |
|
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
|
1 | Q9JIE6 (/ISO) |
|
Antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844
An immune response against microbes mediated by anti-microbial peptides in body fluid.
|
1 | Q9JIE6 (/ISO) |
|
Positive regulation of chemokine (C-C motif) ligand 1 production GO:0071654
Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.
|
1 | Q9JIE6 (/ISO) |
|
Positive regulation of granulocyte colony-stimulating factor production GO:0071657
Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor.
|
1 | Q9JIE6 (/ISO) |
|
Positive regulation of receptor signaling pathway via STAT GO:1904894
Any process that activates or increases the frequency, rate or extent of receptor signaling pathway via STAT.
|
1 | Q9JIE6 (/ISO) |
|
Positive regulation of interleukin-5 secretion GO:2000664
Any process that activates or increases the frequency, rate or extent of interleukin-5 secretion.
|
1 | Q9JIE6 (/ISO) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | Q9JIE6 (/ISO) |
