CATH Superfamily 1.20.1250.10
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 47: Growth hormone d21
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Hormone activity GO:0005179
The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
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4 | P04095 (/IDA) P04095 (/IDA) P04768 (/IDA) P04768 (/IDA) |
|
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
|
4 | P04095 (/IDA) P04095 (/IDA) P04768 (/IDA) P04768 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P04095 (/IPI) P04095 (/IPI) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sprouting angiogenesis GO:0002040
The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.
|
2 | P04095 (/IDA) P04095 (/IDA) |
|
Positive regulation of neuroblast proliferation GO:0002052
Any process that activates or increases the rate of neuroblast proliferation.
|
2 | P04095 (/IDA) P04095 (/IDA) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | P04768 (/IDA) P04768 (/IDA) |
|
Positive regulation of cell projection organization GO:0031346
Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
|
2 | P04095 (/IDA) P04095 (/IDA) |
|
Regulation of microvillus assembly GO:0032534
A process that modulates the formation of a microvillus.
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2 | P04095 (/IDA) P04095 (/IDA) |
|
Positive regulation of blood vessel endothelial cell migration GO:0043536
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
|
2 | P04095 (/IDA) P04095 (/IDA) |
|
Negative regulation of myoblast differentiation GO:0045662
Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
2 | P04095 (/IDA) P04095 (/IDA) |
|
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
|
2 | P04095 (/IDA) P04095 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P04095 (/IDA) P04095 (/IDA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
5 | P04095 (/IDA) P04095 (/IDA) P04768 (/IDA) P04768 (/IDA) Q9JLV9 (/IDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
2 | P04095 (/IDA) P04095 (/IDA) |
