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CATH Superfamily 1.20.120.860

Herpesvirus alkaline exonuclease, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Herpesvirus alkaline exonuclease, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Herpesvirus alkaline exonuclease, N-terminal domain

Representative proteins of this superfamily are SOX (shut off and exonuclease) and its Epstein-Barr virus homolog, BGLF5. Alkaline exonucleases appear to have an important role in the replication of herpes simplex virus, host shutoff at mRNA level and DNA processing. Literature suggests that the N-terminal domain may be involved in undergoing essential interactions with proteins or RNA. DOI:.org/10.1111/j.1742-4658.2009.07374.x

GO Diversity

Unique GO annotations
1 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
41 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 7
Domain clusters (>95% seq id): 2
Domain clusters (>35% seq id): 2
Unique PDBs: 5
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Function
Unique EC:
Unique GO: 1
Taxonomy
Unique Species: 41
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