The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Myosin VI head, motor domain, U50 subdomain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 18: unconventional myosin-XVIIIa isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
5 Q0KI66 (/IDA) Q0KI67 (/IDA) Q7K523 (/IDA) Q8INC3 (/IDA) Q9VEZ0 (/IDA)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Myofibril assembly GO:0030239
Formation of myofibrils, the repeating units of striated muscle.
2 A0A1L3GW42 (/IMP) A0A1W6S8R0 (/IMP)
Sarcomerogenesis GO:0048769
The process in which sarcomeres are added in series within a fiber.
2 A0A1L3GW42 (/IMP) A0A1W6S8R0 (/IMP)
Vasculogenesis GO:0001570
The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.
1 Q9D4I1 (/IMP)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
1 Q9D4I1 (/IMP)
Cardiac muscle fiber development GO:0048739
The process whose specific outcome is the progression of cardiac muscle fiber over time, from its formation to the mature structure.
1 Q9D4I1 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sarcomere GO:0030017
The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
5 Q0KI66 (/IDA) Q0KI67 (/IDA) Q7K523 (/IDA) Q8INC3 (/IDA) Q9VEZ0 (/IDA)
Unconventional myosin complex GO:0016461
A portmanteau term for myosins other than myosin II.
1 Q9D4I1 (/ISO)
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
1 Q9D4I1 (/IDA)
Filamentous actin GO:0031941
A two-stranded helical polymer of the protein actin.
1 Q9D4I1 (/IDA)
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