The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Myosin VI head, motor domain, U50 subdomain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Myosin 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Motor activity GO:0003774
Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate.
13 F4HWY6 (/ISS) F4HXP9 (/ISS) F4I460 (/ISS) F4I5Q6 (/ISS) F4IRU3 (/ISS) F4IUG9 (/ISS) F4IVR7 (/ISS) F4JM19 (/ISS) F4K5J1 (/ISS) F4K7C5 (/ISS)
(3 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 F4IRU3 (/IPI) F4K5J1 (/IPI) Q0WPU1 (/IPI) Q39160 (/IPI) Q9LKB9 (/IPI) Q9LKB9 (/IPI)
Microfilament motor activity GO:0000146
Catalysis of movement along a microfilament, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
2 F4HWY6 (/IMP) F4HXP9 (/IMP)
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
1 F4K7C5 (/IPI)
GTP-dependent protein binding GO:0030742
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) when at least one of the interacting partners is in the GTP-bound state.
1 F4K7C5 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q39160 (/IPI)

There are 26 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin filament-based movement GO:0030048
Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.
13 F4HWY6 (/TAS) F4HXP9 (/TAS) F4I460 (/TAS) F4I5Q6 (/TAS) F4IRU3 (/TAS) F4IUG9 (/TAS) F4IVR7 (/TAS) F4JM19 (/TAS) F4K5J1 (/TAS) F4K7C5 (/TAS)
(3 more)
Trichome morphogenesis GO:0010090
The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana.
3 F4K5J1 (/IGI) F4K7C5 (/IGI) Q39160 (/IGI)
Transport of virus in host, cell to cell GO:0046740
The transport of a virus between adjacent cells in a multicellular organism.
3 B0CN59 (/IMP) B0CN60 (/IMP) B0CN61 (/IMP)
Gynoecium development GO:0048467
The process whose specific outcome is the progression of the gynoecium over time, from its formation to the mature structure. The gynoecium is the collective name for the carpels of a flower.
3 F4K5J1 (/IGI) F4K7C5 (/IGI) Q39160 (/IGI)
Golgi localization GO:0051645
Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell.
3 F4K5J1 (/IMP) F4K7C5 (/IMP) Q39160 (/IMP)
Leaf pavement cell development GO:0090436
The process whose specific outcome is the progression of an leaf pavement cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a leaf pavement cell fate.
3 F4K5J1 (/IGI) F4K7C5 (/IGI) Q39160 (/IGI)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
2 F4HWY6 (/IGI) F4HXP9 (/IGI)
Post-embryonic development GO:0009791
The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.
2 F4K5J1 (/IGI) Q39160 (/IGI)
Unidimensional cell growth GO:0009826
The process in which a cell irreversibly increases in size in one
2 F4K5J1 (/IGI) Q39160 (/IGI)
Pollen tube growth GO:0009860
Growth of pollen via tip extension of the intine wall.
2 F4HWY6 (/IGI) F4HXP9 (/IGI)
Fruit development GO:0010154
The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant.
2 F4K5J1 (/IGI) Q39160 (/IGI)
Root hair elongation GO:0048767
The process in which the root hair grows longer.
2 F4K5J1 (/IMP) F4K7C5 (/IMP)
Cell division GO:0051301
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
2 F4K5J1 (/IGI) Q39160 (/IGI)
Organelle localization GO:0051640
Any process in which an organelle is transported to, and/or maintained in, a specific location.
2 F4HWY6 (/IGI) F4HXP9 (/IGI)
Mitochondrion localization GO:0051646
Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
2 F4K5J1 (/IMP) F4K7C5 (/IMP)
Peroxisome localization GO:0060151
Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
2 F4K5J1 (/IMP) F4K7C5 (/IMP)
Hematopoietic progenitor cell differentiation GO:0002244
The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
1 F1QXS0 (/IMP)
Nuclear migration GO:0007097
The directed movement of the nucleus to a specific location within a cell.
1 Q0WPU1 (/IMP)
Trichome morphogenesis GO:0010090
The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana.
1 F4K5J1 (/IMP)
Trichome branching GO:0010091
Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana.
1 F4K5J1 (/IMP)
Root hair elongation GO:0048767
The process in which the root hair grows longer.
1 F4I460 (/IGI)
Root hair cell tip growth GO:0048768
Localized growth of a plant root hair tip by extension of the cell wall.
1 F4K5J1 (/IMP)
Mitochondrion localization GO:0051646
Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
1 Q39160 (/IGI)
Peroxisome localization GO:0060151
Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
1 Q39160 (/IGI)
Definitive hemopoiesis GO:0060216
A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
1 F1QXS0 (/IMP)
Regulation of establishment or maintenance of cell polarity regulating cell shape GO:2000769
Any process that modulates the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.
1 Q0WPU1 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Myosin complex GO:0016459
A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes.
4 F4HWY6 (/ISS) F4HXP9 (/ISS) F4K7C5 (/ISS) Q9M2K0 (/ISS)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
1 Q9M2K0 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
1 F4K7C5 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
1 F4K5J1 (/IDA)
Unconventional myosin complex GO:0016461
A portmanteau term for myosins other than myosin II.
1 F4IRU3 (/ISS)
Transport vesicle GO:0030133
Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.
1 F4K5J1 (/IDA)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
1 Q0WPU1 (/IDA)
Root hair tip GO:0035619
The tip portion of an outgrowth of a root epidermal cell.
1 F4K5J1 (/IDA)
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