The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Voltage-gated potassium channels. Chain C
".
FunFam 38: Sodium leak channel non-selective protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cation channel activity GO:0005261
Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
4 | Q6Q760 (/ISS) Q8IZF0 (/ISS) Q8IZF0 (/ISS) Q8IZF0 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | Q8BXR5 (/IPI) Q8IZF0 (/IPI) Q8IZF0 (/IPI) Q8IZF0 (/IPI) |
|
Leak channel activity GO:0022840
Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
|
4 | Q6Q760 (/ISS) Q8IZF0 (/ISS) Q8IZF0 (/ISS) Q8IZF0 (/ISS) |
|
Ion channel activity GO:0005216
Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
|
3 | A8JUW5 (/IMP) Q8I877 (/IMP) R9PY25 (/IMP) |
|
Sodium channel activity GO:0005272
Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
3 | Q8IZF0 (/TAS) Q8IZF0 (/TAS) Q8IZF0 (/TAS) |
|
Cation channel activity GO:0005261
Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
1 | Q8BXR5 (/IDA) |
|
Leak channel activity GO:0022840
Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
|
1 | Q8BXR5 (/IMP) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
4 | Q6Q760 (/ISS) Q8IZF0 (/ISS) Q8IZF0 (/ISS) Q8IZF0 (/ISS) |
|
Regulation of resting membrane potential GO:0060075
Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized.
|
4 | Q6Q760 (/ISS) Q8IZF0 (/ISS) Q8IZF0 (/ISS) Q8IZF0 (/ISS) |
|
Calcium ion transmembrane transport GO:0070588
A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
4 | Q6Q760 (/ISS) Q8IZF0 (/ISS) Q8IZF0 (/ISS) Q8IZF0 (/ISS) |
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
4 | Q6Q760 (/ISS) Q8IZF0 (/ISS) Q8IZF0 (/ISS) Q8IZF0 (/ISS) |
|
Adult locomotory behavior GO:0008344
Locomotory behavior in a fully developed and mature organism.
|
3 | A8JUW5 (/IMP) Q8I877 (/IMP) R9PY25 (/IMP) |
|
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
3 | Q8IZF0 (/TAS) Q8IZF0 (/TAS) Q8IZF0 (/TAS) |
|
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
|
3 | A8JUW5 (/IMP) Q8I877 (/IMP) R9PY25 (/IMP) |
|
Regulation of circadian rhythm GO:0042752
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
|
3 | A8JUW5 (/IMP) Q8I877 (/IMP) R9PY25 (/IMP) |
|
Locomotor rhythm GO:0045475
The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
|
3 | A8JUW5 (/IMP) Q8I877 (/IMP) R9PY25 (/IMP) |
|
Circadian behavior GO:0048512
The specific behavior of an organism that recurs with a regularity of approximately 24 hours.
|
3 | A8JUW5 (/IDA) Q8I877 (/IDA) R9PY25 (/IDA) |
|
Sensory perception of touch GO:0050975
The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach).
|
3 | A8JUW5 (/IMP) Q8I877 (/IMP) R9PY25 (/IMP) |
|
Response to anesthetic GO:0072347
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation.
|
3 | A8JUW5 (/IMP) Q8I877 (/IMP) R9PY25 (/IMP) |
|
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | Q8BXR5 (/IDA) |
|
Regulation of resting membrane potential GO:0060075
Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized.
|
1 | Q8BXR5 (/IMP) |
|
Calcium ion transmembrane transport GO:0070588
A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | Q8BXR5 (/IDA) |
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
1 | Q8BXR5 (/IDA) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | Q8IZF0 (/TAS) Q8IZF0 (/TAS) Q8IZF0 (/TAS) |
|
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
3 | A8JUW5 (/IDA) Q8I877 (/IDA) R9PY25 (/IDA) |
|
Axon terminus GO:0043679
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
|
3 | A8JUW5 (/IDA) Q8I877 (/IDA) R9PY25 (/IDA) |
