The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"NAB conserved domain 2
".
FunFam 1: NGFI-A-binding protein 1 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | Q15742 (/IPI) Q15742 (/IPI) Q15742 (/IPI) Q15742 (/IPI) Q15742 (/IPI) Q22002 (/IPI) |
|
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
|
5 | Q15742 (/TAS) Q15742 (/TAS) Q15742 (/TAS) Q15742 (/TAS) Q15742 (/TAS) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
5 | Q15742 (/IPI) Q15742 (/IPI) Q15742 (/IPI) Q15742 (/IPI) Q15742 (/IPI) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
2 | Q61122 (/IDA) Q61127 (/IDA) |
|
Transcription coregulator activity GO:0003712
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators.
|
1 | Q59E55 (/IGI) |
|
Transcription coregulator activity GO:0003712
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators.
|
1 | Q59E55 (/IMP) |
|
Transcription coregulator activity GO:0003712
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators.
|
1 | Q59E55 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q61127 (/ISO) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
8 | Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
8 | Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) |
|
Negative regulation of transcription by RNA polymerase III GO:0016480
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III.
|
5 | Q15742 (/IDA) Q15742 (/IDA) Q15742 (/IDA) Q15742 (/IDA) Q15742 (/IDA) |
|
Positive regulation of tau-protein kinase activity GO:1902949
Any process that activates or increases the frequency, rate or extent of tau-protein kinase activity.
|
5 | Q15742 (/ISS) Q15742 (/ISS) Q15742 (/ISS) Q15742 (/ISS) Q15742 (/ISS) |
|
Endochondral ossification GO:0001958
Replacement ossification wherein bone tissue replaces cartilage.
|
2 | Q61122 (/IGI) Q61127 (/IGI) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q61122 (/IGI) Q61127 (/IGI) |
|
Schwann cell differentiation GO:0014037
The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.
|
2 | Q61122 (/IGI) Q61127 (/IGI) |
|
Myelination GO:0042552
The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
|
2 | Q61122 (/IGI) Q61127 (/IGI) |
|
Regulation of epidermis development GO:0045682
Any process that modulates the frequency, rate or extent of epidermis development.
|
2 | Q61122 (/IGI) Q61127 (/IGI) |
|
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
|
1 | Q59E55 (/IMP) |
|
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
1 | Q59E55 (/IMP) |
|
Neuroblast development GO:0014019
The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron.
|
1 | Q59E55 (/IMP) |
|
Negative regulation of transcription by RNA polymerase III GO:0016480
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III.
|
1 | Q61127 (/ISO) |
|
Wing disc pattern formation GO:0035222
The process giving rise to the pattern of cell differentiation in the wing imaginal disc.
|
1 | Q59E55 (/IMP) |
|
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
|
1 | Q59E55 (/IMP) |
|
Positive regulation of tau-protein kinase activity GO:1902949
Any process that activates or increases the frequency, rate or extent of tau-protein kinase activity.
|
1 | D4A4F4 (/IGI) |
|
Positive regulation of tau-protein kinase activity GO:1902949
Any process that activates or increases the frequency, rate or extent of tau-protein kinase activity.
|
1 | Q61127 (/ISO) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
8 | Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) Q13506 (/NAS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q61127 (/IDA) |
