The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Cardiolipin synthase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841
Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate.
3 Q9UJA2 (/TAS) Q9UJA2 (/TAS) Q9UJA2 (/TAS)
Cardiolipin synthase activity GO:0008808
Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol.
3 Q5U2V5 (/IDA) Q8MZC4 (/IDA) Q8MZC4 (/IDA)
CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity GO:0043337
Catalysis of the reaction: CDP-diacylglycerol + phosphatidylglycerol = CMP + diphosphatidylglycerol.
3 Q9UJA2 (/TAS) Q9UJA2 (/TAS) Q9UJA2 (/TAS)
2-acylglycerol-3-phosphate O-acyltransferase activity GO:0047144
Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA.
3 Q9UJA2 (/TAS) Q9UJA2 (/TAS) Q9UJA2 (/TAS)
Cardiolipin synthase activity GO:0008808
Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol.
1 O01916 (/IMP)
Cardiolipin synthase activity GO:0008808
Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol.
1 Q80ZM8 (/ISO)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cardiolipin biosynthetic process GO:0032049
The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.
3 Q9UJA2 (/TAS) Q9UJA2 (/TAS) Q9UJA2 (/TAS)
Phosphatidylglycerol acyl-chain remodeling GO:0036148
Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains.
3 Q9UJA2 (/TAS) Q9UJA2 (/TAS) Q9UJA2 (/TAS)
ATP biosynthetic process GO:0006754
The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2 Q8MZC4 (/IDA) Q8MZC4 (/IDA)
Mitochondrial membrane organization GO:0007006
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.
2 Q8MZC4 (/IDA) Q8MZC4 (/IDA)
Cardiolipin biosynthetic process GO:0032049
The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.
1 O01916 (/IMP)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
1 O01916 (/IMP)
Regulation of mitochondrial membrane potential GO:0051881
Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
1 O01916 (/IMP)
Response to thyroxine GO:0097068
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.
1 Q5U2V5 (/IDA)
Response to thyroxine GO:0097068
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.
1 Q80ZM8 (/ISO)
Response to phosphatidylethanolamine GO:1905711
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.
1 Q5U2V5 (/IDA)
Response to phosphatidylethanolamine GO:1905711
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.
1 Q80ZM8 (/ISO)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
3 Q9UJA2 (/TAS) Q9UJA2 (/TAS) Q9UJA2 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q80ZM8 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 O01916 (/ISS)
Mitochondrial membrane GO:0031966
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
1 Q5U2V5 (/IDA)
Mitochondrial membrane GO:0031966
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
1 Q80ZM8 (/ISO)
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