The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
HPT domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1: Histidine-containing phosphotransfer protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
12 Q67XQ1 (/IPI) Q67XQ1 (/IPI) Q67XQ1 (/IPI) Q8LNY9 (/IPI) Q9SAZ5 (/IPI) Q9SAZ5 (/IPI) Q9SLX1 (/IPI) Q9ST01 (/IPI) Q9ZNV8 (/IPI) Q9ZNV8 (/IPI)
(2 more)
Histidine phosphotransfer kinase activity GO:0009927
Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.
11 Q8L9T7 (/IDA) Q8L9T7 (/IDA) Q8L9T7 (/IDA) Q9SAZ5 (/IDA) Q9SAZ5 (/IDA) Q9SLX1 (/IDA) Q9ST01 (/IDA) Q9ZNV8 (/IDA) Q9ZNV8 (/IDA) Q9ZNV9 (/IDA)
(1 more)
Protein histidine kinase binding GO:0043424
Interacting selectively and non-covalently with protein histidine kinase.
9 Q8L9T7 (/IPI) Q8L9T7 (/IPI) Q8L9T7 (/IPI) Q9SAZ5 (/IPI) Q9SAZ5 (/IPI) Q9ZNV8 (/IPI) Q9ZNV8 (/IPI) Q9ZNV9 (/IPI) Q9ZNV9 (/IPI)
Histidine phosphotransfer kinase activity GO:0009927
Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.
7 Q8L9T7 (/ISS) Q8L9T7 (/ISS) Q8L9T7 (/ISS) Q9ZNV8 (/ISS) Q9ZNV8 (/ISS) Q9ZNV9 (/ISS) Q9ZNV9 (/ISS)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytokinin-activated signaling pathway GO:0009736
A series of molecular signals generated by the binding of a cytokinin to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.
11 Q8L9T7 (/IMP) Q8L9T7 (/IMP) Q8L9T7 (/IMP) Q9SAZ5 (/IMP) Q9SAZ5 (/IMP) Q9SSC9 (/IMP) Q9SSC9 (/IMP) Q9ZNV8 (/IMP) Q9ZNV8 (/IMP) Q9ZNV9 (/IMP)
(1 more)
Positive regulation of cytokinin-activated signaling pathway GO:0080038
Any process that activates or increases the frequency, rate or extent of cytokinin signaling.
8 Q6VAK3 (/IMP) Q6VAK4 (/IMP) Q6VAK4 (/IMP) Q6VAK4 (/IMP) Q6VAK4 (/IMP) Q6VAK4 (/IMP) Q6VAK4 (/IMP) Q6VAK4 (/IMP)
Antipodal cell differentiation GO:0009557
The process in which an uncellularized nucleus cellularizes and acquires the specialized features of an antipodal cell.
7 Q8L9T7 (/IGI) Q8L9T7 (/IGI) Q8L9T7 (/IGI) Q9SAZ5 (/IGI) Q9SAZ5 (/IGI) Q9ZNV8 (/IGI) Q9ZNV8 (/IGI)
Embryo sac egg cell differentiation GO:0009560
The process in which an uncellularized embryo sac nucleus cellularizes and acquires the specialized features of an egg cell. An example of this process is found in Arabidopsis thaliana.
7 Q8L9T7 (/IGI) Q8L9T7 (/IGI) Q8L9T7 (/IGI) Q9SAZ5 (/IGI) Q9SAZ5 (/IGI) Q9ZNV8 (/IGI) Q9ZNV8 (/IGI)
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
6 Q9SLX1 (/IDA) Q9SSC9 (/IDA) Q9SSC9 (/IDA) Q9ST01 (/IDA) Q9ZNV8 (/IDA) Q9ZNV8 (/IDA)
Cytokinin-activated signaling pathway GO:0009736
A series of molecular signals generated by the binding of a cytokinin to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.
4 Q9ZNV8 (/TAS) Q9ZNV8 (/TAS) Q9ZNV9 (/TAS) Q9ZNV9 (/TAS)
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
3 Q8L9T7 (/TAS) Q8L9T7 (/TAS) Q8L9T7 (/TAS)
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
2 Q9ZNV9 (/IMP) Q9ZNV9 (/IMP)
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
2 Q9SAZ5 (/ISS) Q9SAZ5 (/ISS)
Embryo sac development GO:0009553
The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate.
2 Q9ZNV9 (/IGI) Q9ZNV9 (/IGI)
Response to cytokinin GO:0009735
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.
2 Q9SSC9 (/IEP) Q9SSC9 (/IEP)
Multidimensional cell growth GO:0009825
The process in which a cell irreversibly increases in size in two or three
2 Q9ZNV9 (/IGI) Q9ZNV9 (/IGI)
Xylem development GO:0010089
The formation of the principal water-conducting tissue of a vascular plant.
2 Q9SSC9 (/IMP) Q9SSC9 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
19 Q6VAK3 (/IDA) Q6VAK4 (/IDA) Q6VAK4 (/IDA) Q6VAK4 (/IDA) Q6VAK4 (/IDA) Q6VAK4 (/IDA) Q6VAK4 (/IDA) Q6VAK4 (/IDA) Q8L9T7 (/IDA) Q8L9T7 (/IDA)
(9 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
12 Q6VAK3 (/IDA) Q6VAK4 (/IDA) Q6VAK4 (/IDA) Q6VAK4 (/IDA) Q6VAK4 (/IDA) Q6VAK4 (/IDA) Q6VAK4 (/IDA) Q6VAK4 (/IDA) Q9SLX1 (/IDA) Q9ST01 (/IDA)
(2 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 Q8L9T7 (/IDA) Q8L9T7 (/IDA) Q8L9T7 (/IDA) Q9SAZ5 (/IDA) Q9SAZ5 (/IDA) Q9ZNV8 (/IDA) Q9ZNV8 (/IDA) Q9ZNV9 (/IDA) Q9ZNV9 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q9ZNV8 (/NAS) Q9ZNV8 (/NAS) Q9ZNV9 (/NAS) Q9ZNV9 (/NAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9SSC9 (/ISS) Q9SSC9 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q9SSC9 (/ISS) Q9SSC9 (/ISS)
CATH-Gene3D is a Global Biodata Core Resource Learn more...