The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Putative ATP-dependent RNA helicase DHX36

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 62 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
G-quadruplex RNA binding GO:0002151
Interacting selectively and non-covalently with G-quadruplex RNA structures, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
DNA helicase activity GO:0003678
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
3 Q6P158 (/HDA) Q7Z478 (/HDA) Q9H2U1 (/HDA)
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q6P158 (/IPI) Q8VHK9 (/IPI) Q9H2U1 (/IPI)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
3 D4A2Z8 (/ISS) Q8VHK9 (/ISS) Q9H2U1 (/ISS)
MRNA 3'-UTR AU-rich region binding GO:0035925
Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Ribosomal small subunit binding GO:0043024
Interacting selectively and non-covalently with any part of the small ribosomal subunit.
3 A3KMI0 (/ISS) O60114 (/ISS) Q6PGC1 (/ISS)
MRNA 5'-UTR binding GO:0048027
Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
G-quadruplex DNA binding GO:0051880
Interacting selectively and non-covalently with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.
3 Q05B79 (/IDA) Q8VHK9 (/IDA) Q9H2U1 (/IDA)
G-quadruplex DNA binding GO:0051880
Interacting selectively and non-covalently with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Telomerase RNA binding GO:0070034
Interacting selectively and non-covalently with the telomerase RNA template.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Pre-miRNA binding GO:0070883
Interacting selectively and non-covalently with a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA.
3 Q05B79 (/ISS) Q8VHK9 (/ISS) Q9H2U1 (/ISS)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
2 Q05B79 (/IDA) Q9H2U1 (/IDA)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
2 Q8VHK9 (/IDA) Q9H2U1 (/IDA)
G-quadruplex RNA binding GO:0002151
Interacting selectively and non-covalently with G-quadruplex RNA structures, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.
2 Q8SWT2 (/IDA) Q9H2U1 (/IDA)
DNA helicase activity GO:0003678
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
2 Q8SWT2 (/IDA) Q9H2U1 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2 Q581T1 (/IDA) Q9H2U1 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2 Q4Q2M1 (/ISO) Q8VHK9 (/ISO)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2 Q05B79 (/ISS) Q9VZ55 (/ISS)
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
2 Q8SWT2 (/IDA) Q9H2U1 (/IDA)
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
2 O60114 (/ISO) Q8VHK9 (/ISO)
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
2 Q8VHK9 (/IDA) Q9H2U1 (/IDA)
Helicase activity GO:0004386
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
2 Q8SWT2 (/ISS) Q9VZ55 (/ISS)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q8VHK9 (/ISO)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
1 Q8VHK9 (/ISO)
G-quadruplex RNA binding GO:0002151
Interacting selectively and non-covalently with G-quadruplex RNA structures, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.
1 Q9H2U1 (/IMP)
G-quadruplex RNA binding GO:0002151
Interacting selectively and non-covalently with G-quadruplex RNA structures, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.
1 Q8VHK9 (/ISO)
DNA helicase activity GO:0003678
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
1 Q8VHK9 (/IMP)
DNA helicase activity GO:0003678
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
1 Q8VHK9 (/ISO)
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
1 Q9H2U1 (/IDA)
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
1 Q8VHK9 (/ISO)
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
1 Q8VHK9 (/ISO)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
1 Q581T1 (/IDA)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
1 Q4Q2M1 (/ISO)
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
1 Q9H2U1 (/IDA)
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
1 Q8VHK9 (/ISO)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q05B79 (/IDA)
DNA-dependent ATPase activity GO:0008094
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction.
1 Q9H2U1 (/IDA)
DNA-dependent ATPase activity GO:0008094
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction.
1 Q8VHK9 (/ISO)
DNA-dependent ATPase activity GO:0008094
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction.
1 Q8VHK9 (/ISS)
3'-5' RNA helicase activity GO:0034458
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 3' to 5'.
1 Q581T1 (/IMP)
3'-5' RNA helicase activity GO:0034458
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 3' to 5'.
1 Q4Q2M1 (/ISO)
MRNA 3'-UTR AU-rich region binding GO:0035925
Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule.
1 Q9H2U1 (/IDA)
MRNA 3'-UTR AU-rich region binding GO:0035925
Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule.
1 Q8VHK9 (/ISO)
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
1 Q8VHK9 (/IDA)
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
1 Q9H2U1 (/ISS)
Ribosomal small subunit binding GO:0043024
Interacting selectively and non-covalently with any part of the small ribosomal subunit.
1 Q7Z478 (/IDA)
Ribosomal small subunit binding GO:0043024
Interacting selectively and non-covalently with any part of the small ribosomal subunit.
1 Q6PGC1 (/ISO)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1 Q8VHK9 (/IDA)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1 Q9H2U1 (/ISS)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
1 Q7Z478 (/HDA)
MRNA 5'-UTR binding GO:0048027
Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule.
1 Q9H2U1 (/IDA)
MRNA 5'-UTR binding GO:0048027
Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule.
1 Q8VHK9 (/ISO)
G-quadruplex DNA binding GO:0051880
Interacting selectively and non-covalently with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.
1 Q8VHK9 (/ISO)
Telomerase RNA binding GO:0070034
Interacting selectively and non-covalently with the telomerase RNA template.
1 Q9H2U1 (/IDA)
Telomerase RNA binding GO:0070034
Interacting selectively and non-covalently with the telomerase RNA template.
1 Q8VHK9 (/ISO)
Pre-miRNA binding GO:0070883
Interacting selectively and non-covalently with a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA.
1 D4A2Z8 (/IDA)
Pre-miRNA binding GO:0070883
Interacting selectively and non-covalently with a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA.
1 Q8VHK9 (/ISO)

There are 86 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
G-quadruplex DNA unwinding GO:0044806
The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'.
4 Q05B79 (/IDA) Q8SWT2 (/IDA) Q8VHK9 (/IDA) Q9H2U1 (/IDA)
Regulation of transcription by RNA polymerase III GO:0006359
Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q9H2U1 (/ISS)
RNA secondary structure unwinding GO:0010501
The process in which a secondary structure of RNA are broken or 'melted'.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Positive regulation of mRNA 3'-end processing GO:0031442
Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Cellular response to UV GO:0034644
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q9H2U1 (/ISS)
Regulation of mRNA stability GO:0043488
Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
G-quadruplex DNA unwinding GO:0044806
The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Regulation of embryonic development GO:0045995
Any process that modulates the frequency, rate or extent of embryonic development.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q9H2U1 (/ISS)
Positive regulation of cardioblast differentiation GO:0051891
Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q9H2U1 (/ISS)
Positive regulation of transcription initiation from RNA polymerase II promoter GO:0060261
Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Positive regulation of dendritic spine morphogenesis GO:0061003
Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
3 Q05B79 (/ISS) Q8VHK9 (/ISS) Q9H2U1 (/ISS)
3'-UTR-mediated mRNA destabilization GO:0061158
An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Positive regulation of hematopoietic progenitor cell differentiation GO:1901534
Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q9H2U1 (/ISS)
Regulation of transcription from RNA polymerase II promoter involved in spermatogenesis GO:1902064
Any regulation of transcription from RNA polymerase II promoter that is involved in spermatogenesis.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q9H2U1 (/ISS)
Positive regulation of intracellular mRNA localization GO:1904582
Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization.
3 Q05B79 (/ISS) Q8VHK9 (/ISS) Q9H2U1 (/ISS)
Positive regulation of cytoplasmic translation GO:2000767
Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 Q05B79 (/ISS) Q9H2U1 (/ISS)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
2 Q05B79 (/ISS) Q8VHK9 (/ISS)
Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:1900153
Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
2 Q05B79 (/ISS) Q8VHK9 (/ISS)
Cellular response to arsenite ion GO:1903843
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus.
2 Q05B79 (/ISS) Q8VHK9 (/ISS)
Positive regulation of telomere maintenance via telomere lengthening GO:1904358
Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening.
2 Q05B79 (/ISS) Q8VHK9 (/ISS)
Mitochondrial RNA processing GO:0000963
The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.
1 Q581T1 (/IC)
Ossification GO:0001503
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
1 Q8VHK9 (/IMP)
Ossification GO:0001503
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
1 Q9H2U1 (/ISS)
Cytoplasmic translational initiation GO:0002183
The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
1 O60114 (/ISO)
Positive regulation of myeloid dendritic cell cytokine production GO:0002735
Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production.
1 Q8VHK9 (/IMP)
Regulation of transcription by RNA polymerase III GO:0006359
Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III.
1 Q9H2U1 (/IMP)
Regulation of transcription by RNA polymerase III GO:0006359
Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III.
1 Q8VHK9 (/ISO)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 Q8VHK9 (/IDA)
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
1 Q8VHK9 (/IMP)
RNA secondary structure unwinding GO:0010501
The process in which a secondary structure of RNA are broken or 'melted'.
1 Q9H2U1 (/IDA)
RNA secondary structure unwinding GO:0010501
The process in which a secondary structure of RNA are broken or 'melted'.
1 Q8VHK9 (/ISO)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 D4A2Z8 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q8VHK9 (/ISO)
Cytidine to uridine editing GO:0016554
The conversion of a cytosine residue to uridine in an RNA molecule by deamination.
1 Q581T1 (/IDA)
Cytidine to uridine editing GO:0016554
The conversion of a cytosine residue to uridine in an RNA molecule by deamination.
1 Q4Q2M1 (/ISO)
MRNA modification GO:0016556
The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
1 Q581T1 (/IMP)
MRNA modification GO:0016556
The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
1 Q4Q2M1 (/ISO)
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
1 Q9H2U1 (/IDA)
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
1 Q8VHK9 (/ISO)
Positive regulation of mRNA 3'-end processing GO:0031442
Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing.
1 Q9H2U1 (/IMP)
Positive regulation of mRNA 3'-end processing GO:0031442
Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing.
1 Q8VHK9 (/ISO)
Positive regulation of telomere maintenance GO:0032206
Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
1 Q9H2U1 (/IMP)
Positive regulation of telomere maintenance GO:0032206
Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
1 Q8VHK9 (/ISO)
Positive regulation of telomere maintenance GO:0032206
Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
1 Q8VHK9 (/ISS)
Positive regulation of type I interferon production GO:0032481
Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
1 Q9H2U1 (/TAS)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 Q9H2U1 (/IDA)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 Q8VHK9 (/ISO)
Cellular response to UV GO:0034644
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
1 Q9H2U1 (/IMP)
Cellular response to UV GO:0034644
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
1 Q8VHK9 (/ISO)
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
1 Q8VHK9 (/IMP)
Response to exogenous dsRNA GO:0043330
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.
1 Q8VHK9 (/IMP)
Regulation of mRNA stability GO:0043488
Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
1 Q9H2U1 (/IMP)
Regulation of mRNA stability GO:0043488
Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
1 Q8VHK9 (/ISO)
G-quadruplex DNA unwinding GO:0044806
The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'.
1 Q8VHK9 (/ISO)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q8VHK9 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q9H2U1 (/ISS)
Regulation of embryonic development GO:0045995
Any process that modulates the frequency, rate or extent of embryonic development.
1 Q8VHK9 (/IMP)
MRNA stabilization GO:0048255
Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.
1 Q581T1 (/IDA)
MRNA stabilization GO:0048255
Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.
1 Q4Q2M1 (/ISO)
Positive regulation of cardioblast differentiation GO:0051891
Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
1 Q8VHK9 (/IMP)
Positive regulation of transcription initiation from RNA polymerase II promoter GO:0060261
Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
1 Q9H2U1 (/IMP)
Positive regulation of transcription initiation from RNA polymerase II promoter GO:0060261
Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
1 Q8VHK9 (/ISO)
Positive regulation of dendritic spine morphogenesis GO:0061003
Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
1 D4A2Z8 (/IMP)
Positive regulation of dendritic spine morphogenesis GO:0061003
Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
1 Q8VHK9 (/ISO)
3'-UTR-mediated mRNA destabilization GO:0061158
An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
1 Q9H2U1 (/IMP)
3'-UTR-mediated mRNA destabilization GO:0061158
An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
1 Q8VHK9 (/ISO)
Telomerase RNA stabilization GO:0090669
Prevention of degradation of telomerase RNA (TERC) molecules.
1 Q9H2U1 (/IDA)
Telomerase RNA stabilization GO:0090669
Prevention of degradation of telomerase RNA (TERC) molecules.
1 Q8VHK9 (/ISO)
Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:1900153
Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
1 Q9H2U1 (/IMP)
Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:1900153
Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
1 Q8VHK9 (/ISO)
Positive regulation of hematopoietic progenitor cell differentiation GO:1901534
Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation.
1 Q8VHK9 (/IMP)
Regulation of transcription from RNA polymerase II promoter involved in spermatogenesis GO:1902064
Any regulation of transcription from RNA polymerase II promoter that is involved in spermatogenesis.
1 Q8VHK9 (/IMP)
Positive regulation of interferon-alpha secretion GO:1902741
Any process that activates or increases the frequency, rate or extent of interferon-alpha secretion.
1 Q9H2U1 (/IMP)
Positive regulation of interferon-alpha secretion GO:1902741
Any process that activates or increases the frequency, rate or extent of interferon-alpha secretion.
1 Q8VHK9 (/ISO)
Cellular response to arsenite ion GO:1903843
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus.
1 Q9H2U1 (/IDA)
Cellular response to arsenite ion GO:1903843
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus.
1 Q8VHK9 (/ISO)
Positive regulation of telomere maintenance via telomere lengthening GO:1904358
Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening.
1 Q9H2U1 (/IMP)
Positive regulation of telomere maintenance via telomere lengthening GO:1904358
Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening.
1 Q8VHK9 (/ISO)
Positive regulation of intracellular mRNA localization GO:1904582
Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization.
1 D4A2Z8 (/IMP)
Positive regulation of intracellular mRNA localization GO:1904582
Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization.
1 Q8VHK9 (/ISO)
Positive regulation of cytoplasmic translation GO:2000767
Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.
1 Q9H2U1 (/IMP)
Positive regulation of cytoplasmic translation GO:2000767
Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.
1 Q8VHK9 (/ISO)

There are 47 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromosome, telomeric region GO:0000781
The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q4Q2M1 (/ISO) Q4Q384 (/ISO) Q8VHK9 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 E7EWK3 (/IDA) Q8VHK9 (/IDA) Q9H2U1 (/IDA)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
3 D4A2Z8 (/ISS) Q05B79 (/ISS) Q8VHK9 (/ISS)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
3 Q05B79 (/ISS) Q8VHK9 (/ISS) Q9H2U1 (/ISS)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
3 Q05B79 (/ISS) Q8VHK9 (/ISS) Q9H2U1 (/ISS)
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
3 Q05B79 (/ISS) Q8VHK9 (/ISS) Q9H2U1 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 E7EWK3 (/IDA) Q9H2U1 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q581T1 (/IDA) Q9H2U1 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q4Q2M1 (/ISO) Q4Q384 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 D4A2Z8 (/ISS) Q05B79 (/ISS)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
2 Q05B79 (/ISS) Q8VHK9 (/ISS)
Eukaryotic 43S preinitiation complex GO:0016282
A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA.
2 A3KMI0 (/ISS) Q6PGC1 (/ISS)
Kinetoplast GO:0020023
A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.
2 Q4Q2M1 (/ISO) Q4Q384 (/ISO)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
2 Q4Q2M1 (/ISO) Q4Q384 (/ISO)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
2 Q4Q2M1 (/ISO) Q4Q384 (/ISO)
Chromosome, telomeric region GO:0000781
The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins.
1 Q9H2U1 (/IDA)
Chromosome, telomeric region GO:0000781
The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins.
1 Q8VHK9 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q8VHK9 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q6PGC1 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q581T1 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8VHK9 (/NAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q581T1 (/RCA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O60114 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8VHK9 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9H2U1 (/TAS)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
1 Q9H2U1 (/IDA)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
1 Q8VHK9 (/ISO)
Eukaryotic 43S preinitiation complex GO:0016282
A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA.
1 Q7Z478 (/IDA)
Eukaryotic 43S preinitiation complex GO:0016282
A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA.
1 Q6PGC1 (/ISO)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
1 Q9H2U1 (/IDA)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
1 Q8VHK9 (/ISO)
Kinetoplast GO:0020023
A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.
1 Q581T1 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 D4A2Z8 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 Q8VHK9 (/ISO)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 D4A2Z8 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 Q8VHK9 (/ISO)
Mitochondrial mRNA editing complex GO:0031019
An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.
1 Q581T1 (/IDA)
Mitochondrial mRNA editing complex GO:0031019
An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.
1 Q4Q2M1 (/ISO)
Mitochondrial mRNA editing complex GO:0031019
An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.
1 Q581T1 (/RCA)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
1 Q581T1 (/IDA)
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
1 D4A2Z8 (/IDA)
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
1 Q8VHK9 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q9H2U1 (/HDA)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 Q581T1 (/IDA)
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