The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Rhodopsin 7-helix transmembrane proteins
".
FunFam 94: Vasopressin V1a receptor
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 14 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Vasopressin receptor activity GO:0005000
Combining with vasopressin to initiate a change in cell activity.
|
5 | P30560 (/TAS) P37288 (/TAS) P37288 (/TAS) P47901 (/TAS) P48974 (/TAS) |
Vasopressin receptor activity GO:0005000
Combining with vasopressin to initiate a change in cell activity.
|
3 | Q62463 (/ISO) Q62463 (/ISO) Q9WU02 (/ISO) |
Protein kinase C binding GO:0005080
Interacting selectively and non-covalently with protein kinase C.
|
3 | P37288 (/TAS) P37288 (/TAS) P47901 (/TAS) |
Peptide hormone binding GO:0017046
Interacting selectively and non-covalently with any peptide with hormonal activity in animals.
|
3 | Q62463 (/ISO) Q62463 (/ISO) Q9WU02 (/ISO) |
Vasopressin receptor activity GO:0005000
Combining with vasopressin to initiate a change in cell activity.
|
2 | P30560 (/IDA) P48974 (/IDA) |
Vasopressin receptor activity GO:0005000
Combining with vasopressin to initiate a change in cell activity.
|
2 | P30560 (/IMP) P48974 (/IMP) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P37288 (/IPI) P37288 (/IPI) |
Peptide hormone binding GO:0017046
Interacting selectively and non-covalently with any peptide with hormonal activity in animals.
|
2 | P30560 (/IMP) P48974 (/IMP) |
V1A vasopressin receptor binding GO:0031894
Interacting selectively and non-covalently with a V1A vasopressin receptor.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
G protein-coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
1 | P48974 (/TAS) |
Peptide hormone binding GO:0017046
Interacting selectively and non-covalently with any peptide with hormonal activity in animals.
|
1 | P48974 (/IDA) |
V1A vasopressin receptor binding GO:0031894
Interacting selectively and non-covalently with a V1A vasopressin receptor.
|
1 | P30560 (/IDA) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P48974 (/IDA) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q9WU02 (/ISO) |
There are 70 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
4 | P37288 (/TAS) P37288 (/TAS) P47901 (/TAS) P48974 (/TAS) |
Regulation of systemic arterial blood pressure by vasopressin GO:0001992
The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport.
|
3 | Q62463 (/IGI) Q62463 (/IGI) Q9WU02 (/IGI) |
Activation of phospholipase C activity GO:0007202
The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand.
|
3 | P37288 (/TAS) P37288 (/TAS) P47901 (/TAS) |
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
3 | P37288 (/TAS) P37288 (/TAS) P47901 (/TAS) |
Maternal aggressive behavior GO:0002125
Aggressive behavior of a female to protect her offspring from a threat.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Positive regulation of systemic arterial blood pressure GO:0003084
The process that increases the force with which blood travels through the systemic arterial circulatory system.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Generation of precursor metabolites and energy GO:0006091
The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
|
2 | P37288 (/TAS) P37288 (/TAS) |
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
2 | P30560 (/IMP) P48974 (/IMP) |
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Negative regulation of female receptivity GO:0007621
Any process that stops, prevents or reduces the receptiveness of a female to male advances.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Grooming behavior GO:0007625
The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Blood circulation GO:0008015
The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products.
|
2 | P37288 (/TAS) P37288 (/TAS) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Response to inorganic substance GO:0010035
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Positive regulation of heart rate GO:0010460
Any process that activates or increases the frequency or rate of heart contraction.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Positive regulation of glutamate secretion GO:0014049
Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.
|
2 | P30560 (/IMP) P48974 (/IMP) |
Positive regulation of glutamate secretion GO:0014049
Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Positive regulation of prostaglandin biosynthetic process GO:0031394
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Positive regulation of cellular pH reduction GO:0032849
Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell.
|
2 | P30560 (/IMP) P48974 (/IMP) |
Positive regulation of cellular pH reduction GO:0032849
Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Positive regulation of renal sodium excretion GO:0035815
Any process that increases the amount of sodium excreted in urine over a unit of time.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Maternal behavior GO:0042711
Female behaviors associated with the care and rearing of offspring.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Sperm ejaculation GO:0042713
The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Penile erection GO:0043084
The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Response to peptide hormone GO:0043434
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
|
2 | F1NVW1 (/IMP) Q90YN1 (/IMP) |
Positive regulation of blood pressure GO:0045777
Any process in which the force of blood traveling through the circulatory system is increased.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Positive regulation of vasoconstriction GO:0045907
Any process that activates or increases the frequency, rate or extent of vasoconstriction.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Negative regulation of transmission of nerve impulse GO:0051970
Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Positive regulation of inositol phosphate biosynthetic process GO:0060732
Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
|
2 | F1NVW1 (/IMP) Q90YN1 (/IMP) |
Positive regulation of calcium ion import GO:0090280
Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
|
2 | F1NVW1 (/IMP) Q90YN1 (/IMP) |
Regulation of systemic arterial blood pressure by vasopressin GO:0001992
The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport.
|
1 | P30560 (/TAS) |
Maternal aggressive behavior GO:0002125
Aggressive behavior of a female to protect her offspring from a threat.
|
1 | P30560 (/IMP) |
Positive regulation of systemic arterial blood pressure GO:0003084
The process that increases the force with which blood travels through the systemic arterial circulatory system.
|
1 | P30560 (/IMP) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
1 | P48974 (/IDA) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
1 | P30560 (/NAS) |
Adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO:0007188
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP (cAMP).
|
1 | P48974 (/IDA) |
Negative regulation of female receptivity GO:0007621
Any process that stops, prevents or reduces the receptiveness of a female to male advances.
|
1 | P30560 (/IMP) |
Grooming behavior GO:0007625
The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.
|
1 | P30560 (/IMP) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | P30560 (/IMP) |
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
|
1 | P30560 (/IMP) |
Response to inorganic substance GO:0010035
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
|
1 | P30560 (/IMP) |
Positive regulation of heart rate GO:0010460
Any process that activates or increases the frequency or rate of heart contraction.
|
1 | P30560 (/IMP) |
Myotube differentiation GO:0014902
The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
|
1 | P30560 (/IEP) |
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
|
1 | P30560 (/IMP) |
Telencephalon development GO:0021537
The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.
|
1 | P30560 (/IEP) |
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
|
1 | P30560 (/IMP) |
Positive regulation of prostaglandin biosynthetic process GO:0031394
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
|
1 | P30560 (/IMP) |
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
|
1 | P30560 (/IDA) |
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
|
1 | P30560 (/IEP) |
Positive regulation of urine volume GO:0035810
Any process that increases the amount of urine excreted from the body over a unit of time.
|
1 | P30560 (/NAS) |
Positive regulation of renal sodium excretion GO:0035815
Any process that increases the amount of sodium excreted in urine over a unit of time.
|
1 | P30560 (/IMP) |
Hyperosmotic salinity response GO:0042538
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
|
1 | P48974 (/IEP) |
Cellular response to water deprivation GO:0042631
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water.
|
1 | P30560 (/IEP) |
Maternal behavior GO:0042711
Female behaviors associated with the care and rearing of offspring.
|
1 | P30560 (/IMP) |
Sperm ejaculation GO:0042713
The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract.
|
1 | P30560 (/IMP) |
Penile erection GO:0043084
The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
|
1 | P30560 (/IMP) |
Response to peptide hormone GO:0043434
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
|
1 | G1MWJ6 (/ISS) |
Positive regulation of blood pressure GO:0045777
Any process in which the force of blood traveling through the circulatory system is increased.
|
1 | P30560 (/IMP) |
Positive regulation of glycogen catabolic process GO:0045819
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.
|
1 | P30560 (/NAS) |
Positive regulation of vasoconstriction GO:0045907
Any process that activates or increases the frequency, rate or extent of vasoconstriction.
|
1 | P30560 (/IMP) |
Response to corticosterone GO:0051412
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.
|
1 | P30560 (/IEP) |
Regulation of corticotropin secretion GO:0051459
Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.
|
1 | P30560 (/NAS) |
Negative regulation of transmission of nerve impulse GO:0051970
Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
|
1 | P30560 (/IMP) |
Male mating behavior GO:0060179
The specific behavior of a male organism that is associated with reproduction.
|
1 | Q9WTV8 (/IMP) |
Positive regulation of inositol phosphate biosynthetic process GO:0060732
Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
|
1 | G1MWJ6 (/ISS) |
Positive regulation of calcium ion import GO:0090280
Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
|
1 | G1MWJ6 (/ISS) |
There are 17 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
6 | A8CWP8 (/IDA) A8CWP8 (/IDA) F1NVW1 (/IDA) P30560 (/IDA) P48974 (/IDA) Q90YN1 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | A8CWP8 (/IDA) A8CWP8 (/IDA) F1NVW1 (/IDA) Q90YN1 (/IDA) |
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
|
4 | A8CWP8 (/IDA) A8CWP8 (/IDA) F1NVW1 (/IDA) Q90YN1 (/IDA) |
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
|
3 | P37288 (/TAS) P37288 (/TAS) P47901 (/TAS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | Q62463 (/ISO) Q62463 (/ISO) Q9WU02 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | P37288 (/TAS) P37288 (/TAS) P47901 (/TAS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | P37288 (/TAS) P37288 (/TAS) P47901 (/TAS) |
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
|
2 | A8CWP8 (/IDA) A8CWP8 (/IDA) |
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
|
2 | Q62463 (/ISO) Q62463 (/ISO) |
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
2 | A8CWP8 (/IDA) A8CWP8 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | G1MWJ6 (/ISS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | G1MWJ6 (/ISS) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P48974 (/IDA) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q9WU02 (/ISO) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P30560 (/NAS) |
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
|
1 | P30560 (/IDA) |
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
|
1 | G1MWJ6 (/ISS) |