The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Rhodopsin 7-helix transmembrane proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 90: Long-wave-sensitive opsin 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
7 O18910 (/ISS) O18910 (/ISS) O18911 (/ISS) O35476 (/ISS) O35478 (/ISS) O35599 (/ISS) Q9R024 (/ISS)
Chloride ion binding GO:0031404
Interacting selectively and non-covalently with chloride ions (Cl-).
5 A0A097IR42 (/ISS) P41592 (/ISS) Q9IA33 (/ISS) Q9W771 (/ISS) W0C6H9 (/ISS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
5 A0A097IR42 (/ISS) P41592 (/ISS) Q9IA33 (/ISS) Q9W771 (/ISS) W0C6H9 (/ISS)
Photoreceptor activity GO:0009881
The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.
4 P04000 (/IMP) P04001 (/IMP) P04001 (/IMP) P04001 (/IMP)
Photoreceptor activity GO:0009881
The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.
4 P04000 (/TAS) P04001 (/TAS) P04001 (/TAS) P04001 (/TAS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
3 P04001 (/IDA) P04001 (/IDA) P04001 (/IDA)
Red or far-red light photoreceptor activity GO:0009883
The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660-730nm. The response may involve a change in conformation.
2 Q9W6A7 (/NAS) Q9W6A7 (/NAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 O35599 (/IPI)
Photoreceptor activity GO:0009881
The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.
1 O35599 (/ISO)
Chloride ion binding GO:0031404
Interacting selectively and non-covalently with chloride ions (Cl-).
1 P22329 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P22329 (/IDA)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Light absorption GO:0016037
The reception of a photon by a cell.
5 A0A097IR42 (/ISS) P41592 (/ISS) Q9IA33 (/ISS) Q9W771 (/ISS) W0C6H9 (/ISS)
Absorption of visible light GO:0016038
The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.
5 A0A097IR42 (/ISS) P41592 (/ISS) Q9IA33 (/ISS) Q9W771 (/ISS) W0C6H9 (/ISS)
Protein-chromophore linkage GO:0018298
The covalent or noncovalent attachment of a chromophore to a protein.
5 A0A097IR42 (/ISS) P41592 (/ISS) Q9IA33 (/ISS) Q9W771 (/ISS) W0C6H9 (/ISS)
Protein homotrimerization GO:0070207
The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
5 A0A097IR42 (/ISS) P41592 (/ISS) Q9IA33 (/ISS) Q9W771 (/ISS) W0C6H9 (/ISS)
Retinoid metabolic process GO:0001523
The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
4 P04000 (/TAS) P04001 (/TAS) P04001 (/TAS) P04001 (/TAS)
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
4 P04000 (/TAS) P04001 (/TAS) P04001 (/TAS) P04001 (/TAS)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
4 P04000 (/TAS) P04001 (/TAS) P04001 (/TAS) P04001 (/TAS)
Absorption of visible light GO:0016038
The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.
4 O12948 (/IDA) P22329 (/IDA) W5KG21 (/IDA) W5KG21 (/IDA)
Absorption of UV light GO:0016039
The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm.
4 O12948 (/IDA) P22329 (/IDA) W5KG21 (/IDA) W5KG21 (/IDA)
Positive regulation of cytokinesis GO:0032467
Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.
4 P04000 (/IMP) P04001 (/IMP) P04001 (/IMP) P04001 (/IMP)
Absorption of UV light GO:0016039
The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm.
3 A0A097IR42 (/ISS) Q9IA33 (/ISS) W0C6H9 (/ISS)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
2 Q9W6A7 (/NAS) Q9W6A7 (/NAS)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
2 Q9W6A7 (/IDA) Q9W6A7 (/IDA)
Photoperiodism GO:0009648
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species.
2 Q9W6A7 (/IDA) Q9W6A7 (/IDA)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 P04000 (/TAS)
Light absorption GO:0016037
The reception of a photon by a cell.
1 P22329 (/IDA)
Protein-chromophore linkage GO:0018298
The covalent or noncovalent attachment of a chromophore to a protein.
1 P22329 (/IDA)
Positive regulation of cytokinesis GO:0032467
Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.
1 O35599 (/ISO)
Protein homotrimerization GO:0070207
The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
1 P22329 (/IDA)

There are 15 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
7 O18910 (/ISS) O18910 (/ISS) O18911 (/ISS) O35476 (/ISS) O35478 (/ISS) O35599 (/ISS) Q9R024 (/ISS)
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
5 A0A097IR42 (/ISS) P41592 (/ISS) Q9IA33 (/ISS) Q9W771 (/ISS) W0C6H9 (/ISS)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
5 A0A097IR42 (/ISS) P41592 (/ISS) Q9IA33 (/ISS) Q9W771 (/ISS) W0C6H9 (/ISS)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
5 A0A097IR42 (/ISS) P41592 (/ISS) Q9IA33 (/ISS) Q9W771 (/ISS) W0C6H9 (/ISS)
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
5 A0A097IR42 (/ISS) P41592 (/ISS) Q9IA33 (/ISS) Q9W771 (/ISS) W0C6H9 (/ISS)
Photoreceptor inner segment membrane GO:0060342
The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
5 A0A097IR42 (/ISS) P41592 (/ISS) Q9IA33 (/ISS) Q9W771 (/ISS) W0C6H9 (/ISS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
4 P04000 (/TAS) P04001 (/TAS) P04001 (/TAS) P04001 (/TAS)
Photoreceptor disc membrane GO:0097381
Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane.
4 P04000 (/TAS) P04001 (/TAS) P04001 (/TAS) P04001 (/TAS)
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
3 O35476 (/IDA) O35599 (/IDA) P22329 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 P04001 (/IDA) P04001 (/IDA) P04001 (/IDA)
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
1 O35599 (/ISO)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
1 P22329 (/IDA)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
1 P22329 (/IDA)
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
1 P22329 (/IDA)
Photoreceptor inner segment membrane GO:0060342
The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
1 P22329 (/IDA)
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