The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Rhodopsin 7-helix transmembrane proteins
".
FunFam 145: Oxytocin receptor
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Oxytocin receptor activity GO:0004990
Combining with oxytocin to initiate a change in cell activity.
|
2 | P30559 (/TAS) P30559 (/TAS) |
Oxytocin receptor activity GO:0004990
Combining with oxytocin to initiate a change in cell activity.
|
1 | P70536 (/IDA) |
Oxytocin receptor activity GO:0004990
Combining with oxytocin to initiate a change in cell activity.
|
1 | P97926 (/ISO) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P70536 (/IPI) |
Peptide hormone binding GO:0017046
Interacting selectively and non-covalently with any peptide with hormonal activity in animals.
|
1 | P70536 (/IDA) |
Peptide hormone binding GO:0017046
Interacting selectively and non-covalently with any peptide with hormonal activity in animals.
|
1 | P97926 (/ISO) |
There are 65 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
|
3 | P30559 (/ISS) P30559 (/ISS) P70536 (/ISS) |
Muscle contraction GO:0006936
A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
|
2 | P30559 (/TAS) P30559 (/TAS) |
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
|
2 | P30559 (/TAS) P30559 (/TAS) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
2 | P30559 (/TAS) P30559 (/TAS) |
Female pregnancy GO:0007565
The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.
|
2 | P30559 (/TAS) P30559 (/TAS) |
Lactation GO:0007595
The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young.
|
2 | P30559 (/TAS) P30559 (/TAS) |
Suckling behavior GO:0001967
Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast.
|
1 | P70536 (/IMP) |
Suckling behavior GO:0001967
Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast.
|
1 | P97926 (/ISO) |
Response to amphetamine GO:0001975
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.
|
1 | P70536 (/IMP) |
Response to amphetamine GO:0001975
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.
|
1 | P97926 (/ISO) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
1 | P70536 (/IMP) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
1 | P97926 (/ISO) |
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
1 | P70536 (/IMP) |
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
1 | P97926 (/ISO) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | P70536 (/IEP) |
Female pregnancy GO:0007565
The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.
|
1 | P70536 (/IEP) |
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
|
1 | P70536 (/IMP) |
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
|
1 | P97926 (/ISO) |
Positive regulation of norepinephrine secretion GO:0010701
Any process that increases the frequency, rate or extent of the regulated release of norepinephrine.
|
1 | P70536 (/IMP) |
Positive regulation of norepinephrine secretion GO:0010701
Any process that increases the frequency, rate or extent of the regulated release of norepinephrine.
|
1 | P97926 (/ISO) |
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
1 | P70536 (/IEP) |
Telencephalon development GO:0021537
The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.
|
1 | P70536 (/IEP) |
Sleep GO:0030431
Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.
|
1 | P70536 (/IMP) |
Sleep GO:0030431
Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.
|
1 | P97926 (/ISO) |
Positive regulation of synaptic transmission, GABAergic GO:0032230
Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
|
1 | P70536 (/IMP) |
Positive regulation of synaptic transmission, GABAergic GO:0032230
Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
|
1 | P97926 (/ISO) |
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
|
1 | P70536 (/IEP) |
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
|
1 | P70536 (/IEP) |
Response to anoxia GO:0034059
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.
|
1 | P70536 (/IMP) |
Response to anoxia GO:0034059
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.
|
1 | P97926 (/ISO) |
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
|
1 | P70536 (/IEP) |
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
|
1 | P70536 (/IMP) |
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
|
1 | P97926 (/ISO) |
Response to cocaine GO:0042220
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.
|
1 | P70536 (/IEP) |
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
1 | P70536 (/IEP) |
Maternal behavior GO:0042711
Female behaviors associated with the care and rearing of offspring.
|
1 | P70536 (/IMP) |
Maternal behavior GO:0042711
Female behaviors associated with the care and rearing of offspring.
|
1 | P97926 (/ISO) |
Sperm ejaculation GO:0042713
The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract.
|
1 | P70536 (/IMP) |
Sperm ejaculation GO:0042713
The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract.
|
1 | P97926 (/ISO) |
Eating behavior GO:0042755
The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue.
|
1 | P70536 (/IMP) |
Eating behavior GO:0042755
The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue.
|
1 | P97926 (/ISO) |
Response to peptide hormone GO:0043434
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
|
1 | P70536 (/IEP) |
Regulation of digestive system process GO:0044058
Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
|
1 | P70536 (/IMP) |
Regulation of digestive system process GO:0044058
Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
|
1 | P97926 (/ISO) |
Estrous cycle GO:0044849
A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.
|
1 | P70536 (/IEP) |
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
|
1 | E4W699 (/IMP) |
Positive regulation of blood pressure GO:0045777
Any process in which the force of blood traveling through the circulatory system is increased.
|
1 | P97926 (/IGI) |
Response to steroid hormone GO:0048545
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
|
1 | P70536 (/IMP) |
Response to steroid hormone GO:0048545
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
|
1 | P97926 (/ISO) |
Digestive tract development GO:0048565
The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.
|
1 | P70536 (/IEP) |
Neurohypophysis morphogenesis GO:0048848
The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.
|
1 | E4W699 (/IMP) |
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
1 | P70536 (/IMP) |
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
1 | P97926 (/ISO) |
Positive regulation of synaptic transmission, glutamatergic GO:0051968
Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
|
1 | P70536 (/IMP) |
Positive regulation of synaptic transmission, glutamatergic GO:0051968
Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
|
1 | P97926 (/ISO) |
Maternal process involved in parturition GO:0060137
A reproductive process occurring in the mother that results in birth.
|
1 | P70536 (/IEP) |
Positive regulation of penile erection GO:0060406
Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
|
1 | P70536 (/IMP) |
Positive regulation of penile erection GO:0060406
Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
|
1 | P97926 (/ISO) |
Negative regulation of gastric acid secretion GO:0060455
Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
|
1 | P70536 (/IMP) |
Negative regulation of gastric acid secretion GO:0060455
Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
|
1 | P97926 (/ISO) |
ERK1 and ERK2 cascade GO:0070371
An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
1 | P70536 (/IMP) |
ERK1 and ERK2 cascade GO:0070371
An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
1 | P97926 (/ISO) |
Positive regulation of uterine smooth muscle contraction GO:0070474
Any process that increases the frequency, rate or extent of uterine smooth muscle contraction.
|
1 | P70536 (/IMP) |
Positive regulation of uterine smooth muscle contraction GO:0070474
Any process that increases the frequency, rate or extent of uterine smooth muscle contraction.
|
1 | P97926 (/ISO) |
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
|
1 | P97926 (/IMP) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | P30559 (/TAS) P30559 (/TAS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | P30559 (/TAS) P30559 (/TAS) |
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
|
1 | P70536 (/IDA) |
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
|
1 | P97926 (/ISO) |
Cell-cell adherens junction GO:0005913
An adherens junction which connects a cell to another cell.
|
1 | P70536 (/IDA) |
Cell-cell adherens junction GO:0005913
An adherens junction which connects a cell to another cell.
|
1 | P97926 (/ISO) |
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | P70536 (/IDA) |
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | P97926 (/ISO) |