The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: rRNA adenine N(6)-methyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RRNA (adenine-N6,N6-)-dimethyltransferase activity GO:0000179
Catalysis of the dimethylation two adjacent A residues in the loop closing the 3'-terminal stem of the 18S rRNA, using S-adenosyl-L-methionine as a methyl donor.
9 Q9UNQ2 (/EXP) Q9UNQ2 (/EXP) Q9UNQ2 (/EXP) Q9UNQ2 (/EXP) Q9UNQ2 (/EXP) Q9UNQ2 (/EXP) Q9UNQ2 (/EXP) Q9UNQ2 (/EXP) Q9UNQ2 (/EXP)
RRNA (adenine-N6,N6-)-dimethyltransferase activity GO:0000179
Catalysis of the dimethylation two adjacent A residues in the loop closing the 3'-terminal stem of the 18S rRNA, using S-adenosyl-L-methionine as a methyl donor.
9 Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
9 Q9UNQ2 (/HDA) Q9UNQ2 (/HDA) Q9UNQ2 (/HDA) Q9UNQ2 (/HDA) Q9UNQ2 (/HDA) Q9UNQ2 (/HDA) Q9UNQ2 (/HDA) Q9UNQ2 (/HDA) Q9UNQ2 (/HDA)
RRNA (adenine-N6,N6-)-dimethyltransferase activity GO:0000179
Catalysis of the dimethylation two adjacent A residues in the loop closing the 3'-terminal stem of the 18S rRNA, using S-adenosyl-L-methionine as a methyl donor.
4 Q2KHT8 (/ISS) Q2KHT8 (/ISS) Q95KJ0 (/ISS) Q9D0D4 (/ISS)
RRNA (adenine-N6,N6-)-dimethyltransferase activity GO:0000179
Catalysis of the dimethylation two adjacent A residues in the loop closing the 3'-terminal stem of the 18S rRNA, using S-adenosyl-L-methionine as a methyl donor.
1 Q9D0D4 (/ISO)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RRNA methylation GO:0031167
The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.
9 Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP)
RRNA methylation GO:0031167
The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.
9 Q9UNQ2 (/TAS) Q9UNQ2 (/TAS) Q9UNQ2 (/TAS) Q9UNQ2 (/TAS) Q9UNQ2 (/TAS) Q9UNQ2 (/TAS) Q9UNQ2 (/TAS) Q9UNQ2 (/TAS) Q9UNQ2 (/TAS)
Positive regulation of rRNA processing GO:2000234
Any process that activates or increases the frequency, rate or extent of rRNA processing.
9 Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP) Q9UNQ2 (/IMP)
RRNA methylation GO:0031167
The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.
4 Q2KHT8 (/ISS) Q2KHT8 (/ISS) Q95KJ0 (/ISS) Q9D0D4 (/ISS)
Positive regulation of rRNA processing GO:2000234
Any process that activates or increases the frequency, rate or extent of rRNA processing.
4 Q2KHT8 (/ISS) Q2KHT8 (/ISS) Q95KJ0 (/ISS) Q9D0D4 (/ISS)
RRNA methylation GO:0031167
The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.
1 Q9D0D4 (/ISO)
Positive regulation of rRNA processing GO:2000234
Any process that activates or increases the frequency, rate or extent of rRNA processing.
1 Q9D0D4 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
9 Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
9 Q9UNQ2 (/TAS) Q9UNQ2 (/TAS) Q9UNQ2 (/TAS) Q9UNQ2 (/TAS) Q9UNQ2 (/TAS) Q9UNQ2 (/TAS) Q9UNQ2 (/TAS) Q9UNQ2 (/TAS) Q9UNQ2 (/TAS)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
9 Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
9 Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA) Q9UNQ2 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
4 Q2KHT8 (/ISS) Q2KHT8 (/ISS) Q95KJ0 (/ISS) Q9D0D4 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9D0D4 (/ISO)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q9D0D4 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9D0D4 (/ISO)
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