The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cytochrome c-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: Cytochrome c

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity GO:0045155
Enables the directed movement of electrons from the CoQH2-cytochrome c reductase complex and the cytochrome c oxidase complex.
51 P00002 (/ISS) P00002 (/ISS) P00002 (/ISS) P00002 (/ISS) P00002 (/ISS) P00002 (/ISS) P00002 (/ISS) P00002 (/ISS) P00002 (/ISS) P00002 (/ISS)
(41 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
13 P99999 (/IPI) P99999 (/IPI) P99999 (/IPI) P99999 (/IPI) P99999 (/IPI) P99999 (/IPI) P99999 (/IPI) P99999 (/IPI) P99999 (/IPI) P99999 (/IPI)
(3 more)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
13 P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS)
(3 more)
Electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity GO:0045155
Enables the directed movement of electrons from the CoQH2-cytochrome c reductase complex and the cytochrome c oxidase complex.
13 P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA)
(3 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
13 P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS)
(3 more)
Activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c GO:0008635
Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c.
13 P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS)
(3 more)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
13 P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS)
(3 more)
Cellular respiration GO:0045333
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).
13 P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS)
(3 more)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
51 P00002 (/ISS) P00002 (/ISS) P00002 (/ISS) P00002 (/ISS) P00002 (/ISS) P00002 (/ISS) P00002 (/ISS) P00002 (/ISS) P00002 (/ISS) P00002 (/ISS)
(41 more)
Protein phosphatase type 2A complex GO:0000159
A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
13 P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS)
(3 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
13 P99999 (/HDA) P99999 (/HDA) P99999 (/HDA) P99999 (/HDA) P99999 (/HDA) P99999 (/HDA) P99999 (/HDA) P99999 (/HDA) P99999 (/HDA) P99999 (/HDA)
(3 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
13 P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA)
(3 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
13 P99999 (/HDA) P99999 (/HDA) P99999 (/HDA) P99999 (/HDA) P99999 (/HDA) P99999 (/HDA) P99999 (/HDA) P99999 (/HDA) P99999 (/HDA) P99999 (/HDA)
(3 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
13 P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA)
(3 more)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
13 P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS)
(3 more)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
13 P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA)
(3 more)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
13 P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS)
(3 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
13 P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA) P99999 (/IDA)
(3 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
13 P99999 (/IMP) P99999 (/IMP) P99999 (/IMP) P99999 (/IMP) P99999 (/IMP) P99999 (/IMP) P99999 (/IMP) P99999 (/IMP) P99999 (/IMP) P99999 (/IMP)
(3 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
13 P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS) P99999 (/TAS)
(3 more)
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