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CATH Superfamily 1.10.630.10

Cytochrome P450

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 19: Cytochrome P450 family protein

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2-hydroxyisoflavanone synthase. [EC: 1.14.14.87]
(1) Liquiritigenin + O(2) + [reduced NADPH--hemoprotein reductase] = 2,4',7-trihydroxyisoflavanone + H(2)O + [oxidized NADPH--hemoprotein reductase]. (2) (2S)-naringenin + O(2) + [reduced NADPH--hemoprotein reductase] = 2,4',5,7-tetrahydroxyisoflavanone + H(2)O + [oxidized NADPH--hemoprotein reductase].
  • A cytochrome P450 (heme thiolate) protein found in plants.
  • The reaction involves the migration of the 2-phenyl group of the flavanone to the 3-position of the isoflavanone.
  • The 2-hydroxyl group is derived from the oxygen molecule.
  • EC 4.2.1.105 acts on the products with loss of water and formation of genistein and daidzein, respectively.
  • Formerly EC 1.14.13.86 and EC 1.14.13.136.
 11 A0A0B2QZA2 A0A0B2QZA2 A0A0B2QZA2 G4XV71 K9LH71 K9LH71 K9LH71 Q9SWR5 Q9SWR5 Q9SWR5
(1 more...)
Beta-amyrin 24-hydroxylase. [EC: 1.14.14.134]
(1) Beta-amyrin + [reduced NADPH--hemoprotein reductase] + O(2) = 24-hydroxy-beta-amyrin + [oxidized NADPH--hemoprotein reductase] + H(2)O. (2) Sophoradiol + [reduced NADPH--hemoprotein reductase] + O(2) = 24-hydroxysophoradiol + [oxidized NADPH--hemoprotein reductase] + H(2)O.
  • A cytochrome P450 (heme-thiolate) protein found in plants and participates in the biosynthesis of soybean saponins.
  • Formerly EC 1.14.99.43.
 9 A0A0R0IXC2 A0A0R0IXC2 A0A0R0IXC2 A0A445JP81 A0A445JP81 A0A445JP81 Q9XHC6 Q9XHC6 Q9XHC6
3,9-dihydroxypterocarpan 6A-monooxygenase. [EC: 1.14.14.93]
(6aR,11aR)-3,9-dihydroxypterocarpan + [reduced NADPH--hemoprotein reductase] + O(2) = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + [oxidized NADPH--hemoprotein reductase] + H(2)O.
  • A cytochrome P450 (heme-thiolate) protein found in soybean.
  • The product of the reaction is the biosynthetic precursor of the glyceollin phytoalexins.
  • Formerly EC 1.14.13.28.
 4 A0A0R0KJB1 A0A0R0KJB1 Q42798 Q42798
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