The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Farnesyl Diphosphate Synthase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Geranylgeranyl diphosphate synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Geranyltranstransferase activity GO:0004337
Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate.
108 A0A0H2UXE9 (/IDA) A0A0H2UXE9 (/IDA) A0A0H2UXE9 (/IDA) A0A0H2UXE9 (/IDA) A0A0H2UXE9 (/IDA) A0A0H2UXE9 (/IDA) A6Q6L6 (/IDA) D5LB37 (/IDA) D5LB37 (/IDA) D5LB37 (/IDA)
(98 more)
Dimethylallyltranstransferase activity GO:0004161
Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.
80 P22939 (/IDA) P22939 (/IDA) P22939 (/IDA) P22939 (/IDA) P22939 (/IDA) P22939 (/IDA) P22939 (/IDA) P22939 (/IDA) P22939 (/IDA) P22939 (/IDA)
(70 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
78 P22939 (/IPI) P22939 (/IPI) P22939 (/IPI) P22939 (/IPI) P22939 (/IPI) P22939 (/IPI) P22939 (/IPI) P22939 (/IPI) P22939 (/IPI) P22939 (/IPI)
(68 more)
Geranyltranstransferase activity GO:0004337
Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate.
31 A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS)
(21 more)
Farnesyltranstransferase activity GO:0004311
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
17 O04046 (/IDA) O04046 (/IDA) O04046 (/IDA) O22043 (/IDA) P22873 (/IDA) P34802 (/IDA) P34802 (/IDA) P34802 (/IDA) P80042 (/IDA) P80042 (/IDA)
(7 more)
Farnesyltranstransferase activity GO:0004311
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
6 P17060 (/ISS) P17060 (/ISS) P21684 (/ISS) P48368 (/ISS) P54976 (/ISS) Q9LJY2 (/ISS)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Geranyl diphosphate biosynthetic process GO:0033384
The chemical reactions and pathways resulting in the formation of geranyl diphosphate.
74 P22939 (/IMP) P22939 (/IMP) P22939 (/IMP) P22939 (/IMP) P22939 (/IMP) P22939 (/IMP) P22939 (/IMP) P22939 (/IMP) P22939 (/IMP) P22939 (/IMP)
(64 more)
Farnesyl diphosphate biosynthetic process GO:0045337
The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.
74 P22939 (/IMP) P22939 (/IMP) P22939 (/IMP) P22939 (/IMP) P22939 (/IMP) P22939 (/IMP) P22939 (/IMP) P22939 (/IMP) P22939 (/IMP) P22939 (/IMP)
(64 more)
Farnesyl diphosphate biosynthetic process GO:0045337
The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.
32 A0A0H2UXE9 (/IDA) A0A0H2UXE9 (/IDA) A0A0H2UXE9 (/IDA) A0A0H2UXE9 (/IDA) A0A0H2UXE9 (/IDA) A0A0H2UXE9 (/IDA) A6Q6L6 (/IDA) D5LB37 (/IDA) D5LB37 (/IDA) D5LB37 (/IDA)
(22 more)
Farnesyl diphosphate biosynthetic process GO:0045337
The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.
24 A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS) A0A1S0QWY2 (/ISS)
(14 more)
Isoprenoid biosynthetic process GO:0008299
The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
8 O04046 (/TAS) O04046 (/TAS) O04046 (/TAS) O22043 (/TAS) P34802 (/TAS) P34802 (/TAS) P34802 (/TAS) Q9SLG2 (/TAS)
Geranylgeranyl diphosphate biosynthetic process GO:0033386
The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate.
8 P21684 (/IDA) P22873 (/IDA) Q24K59 (/IDA) Q5ZT35 (/IDA) Q5ZT35 (/IDA) Q6N9M1 (/IDA) Q6SGW1 (/IDA) Q6SGW1 (/IDA)
Geranylgeranyl diphosphate biosynthetic process GO:0033386
The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate.
4 P17060 (/ISS) P17060 (/ISS) P48368 (/ISS) P54976 (/ISS)
Monoterpene biosynthetic process GO:0043693
The chemical reactions and pathways resulting in the formation of monoterpenes, terpenes with a C10 structure.
4 P34802 (/IMP) P34802 (/IMP) P34802 (/IMP) Q39108 (/IMP)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
3 P34802 (/IMP) P34802 (/IMP) P34802 (/IMP)
Isoprenoid metabolic process GO:0006720
The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
2 P80042 (/IDA) P80042 (/IDA)
Isoprenoid biosynthetic process GO:0008299
The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
2 Q2GL13 (/ISS) Q2GL13 (/ISS)
Carotenoid biosynthetic process GO:0016117
The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.
2 Q4W8B2 (/IDA) Q4W8B2 (/IDA)
Coenzyme metabolic process GO:0006732
The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
1 Q60AN0 (/ISS)
Geranyl diphosphate biosynthetic process GO:0033384
The chemical reactions and pathways resulting in the formation of geranyl diphosphate.
1 Q9SBR3 (/IDA)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
77 P22939 (/IDA) P22939 (/IDA) P22939 (/IDA) P22939 (/IDA) P22939 (/IDA) P22939 (/IDA) P22939 (/IDA) P22939 (/IDA) P22939 (/IDA) P22939 (/IDA)
(67 more)
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
5 P34802 (/IDA) P34802 (/IDA) P34802 (/IDA) P80042 (/IDA) P80042 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
4 O04046 (/IDA) O04046 (/IDA) O04046 (/IDA) Q9SLG2 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
4 P34802 (/IDA) P34802 (/IDA) P34802 (/IDA) Q39108 (/IDA)
Etioplast GO:0009513
A plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions.
3 P34802 (/IDA) P34802 (/IDA) P34802 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 O22043 (/IDA)
Stromule GO:0010319
Thin filamentous structure extending from the surface of all plastid types examined so far, including chloroplast, proplastid, etioplast, leucoplast, amyloplast, and chromoplast. In general, stromules are more abundant in tissues containing non-green plastids, and in cells containing smaller plastids. The primary function of stromules is still unresolved, although the presence of stromules markedly increases the plastid surface area, potentially increasing transport to and from the cytosol. Other functions of stromules, such as transfer of macromolecules between plastids and starch granule formation in cereal endosperm, may be restricted to particular tissues and cell types.
1 F8UR58 (/IDA)
Thylakoid membrane GO:0042651
The pigmented membrane of any thylakoid.
1 Q39108 (/IDA)
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